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i)18(n)-2( )30(C)13(o)28(mput)18(at)18(i)-12(o)-2(n)28(a)2(l)18( S)24(c)2(i)18(e)2(nce)33( &)33( E)18(n)-2(g)28(i)-12(ne)33(e)33(r)-18(i)18(n)-2(g)28(,)]TJ T* 0.014 Tc -0.021 Tw [(\()14(I)14(n)-1(s)39(t)19(i)-11(t)19(ut)19(e of)14( E)19(l)-11(ec)34(t)19(i)-11(c)34(a)3(l)-11( and)29( E)-11(l)-11(e)34(ct)19(r)14(o)-1(n)29(i)-11(c)34( )-30( E)-11(n)29(gi)19(nee)34(r)14(i)-11(ngs)39(,)22( N)-22(e)3(w)39( )-30(Y)9(o)29(r)14(k)-1(,)-9( 1995\))14(,)22( p)29(p)-1(.)22( 63\22676.)]TJ -2.2727 -1.1818 TD 0.015 Tc (7.)Tj /F9 1 Tf 0.7576 -0.0217 TD 0 Tc 0 Tw ( )Tj /F5 1 Tf 1.5152 0.0217 TD (")Tj /F7 1 Tf 0.4242 -0.0217 TD 0.005 Tc -0.013 Tw [(V)40(o)-10(x)-6(e)-6(l)-20(V)40(i)10(e)-36(w)36( 2)-10(.)13(5)-10( )-31(Use)-6(r')7(s Gu)-10(i)10(d)-10(e)-6(,)]TJ /F5 1 Tf 11.6061 0.0217 TD -0.006 Tc -0.002 Tw [(")8( )-31(V)-11(ita)-17(l I)-37(m)14(a)-47(g)-21(e)-17(s)19(, I)-37(n)-21(c)14(.)2( )]TJ 0 0 1 rg 8.1515 0 TD 0.005 Tc [(www.)-18(v)20(i)10(t)10(a)-6(l)-20(i)10(m)25(a)-36(g)-10(e)-6(s)30(.)-18(c)25(o)-10(m)]TJ 0 0 0 rg 9.0909 0 TD 0.015 Tc -0.023 Tw [( \()15(1995\))15(.)]TJ ET 0 0 1 rg 1 i 295.32 273.6 71.76 -0.48 re f* BT 7.92 0 0 7.92 117.48 265.612 Tm 0 0 0 rg (8.)Tj /F9 1 Tf 0.7576 -0.0217 TD 0 Tc 0 Tw ( )Tj /F5 1 Tf 1.5152 0.0217 TD 0.013 Tc 0.04 Tw [(H)8(.)21( W)-13(.)21( S)-7(h)-2(en)28( and)28( )-30(C)13(.)21( R)-17(.)21( J)-22(o)28(hns)8(o)28(n)-2(,)21( \223)-28(S)24(emi)18(\226)-2(aut)18(o)-2(m)33(a)2(t)18(i)-12(c)33( i)-12(m)33(a)-28(g)28(e )-30(s)8(e)33(gmen)28(t)18(a)2(t)18(i)-12(on)28(:)18( )-61(A)8( )-30(b)28(i)18(omedi)-12(c)33(al)18( )-33(t)-12(h)28(r)-18(e)2(s)38(h)-2(o)28(l)-12(d)28(i)-12(ng)28( )-30(app)28(r)-18(o)28(ach)28(,)21(\224)]TJ 0 -1.1515 TD 0.014 Tc 0.009 Tw [(T)-11(e)34(ch)29(ni)19(c)34(a)3(l)-11( )31(R)-16(e)34(po)29(r)14(t)-11( U)9(U)39(C)-16(S)25(\22694\22601)29(9,)22( )31(D)9(e)34(pt)19(.)22( of)14( )31(C)14(S)-6(,)22( U)9(n)29(i)-11(v)29(.)22( of)44( U)9(t)19(ah)29( \()14(1994\))14(.)]TJ -2.2727 -1.1818 TD 0.015 Tc (9.)Tj /F9 1 Tf 0.7576 -0.0217 TD 0 Tc 0 Tw ( )Tj /F5 1 Tf 1.5152 0.0217 TD 0.015 Tc 0.068 Tw [(D)10(.)23( F.)23( W)20(a)4(t)-10(s)10(on)30(,)23(.)-8( \223C)15(omp)30(u)0(t)20(i)-10(ng)30( t)-10(h)0(e)35( )]TJ /F7 1 Tf 13.303 -0.0217 TD (n\226)Tj /F5 1 Tf 1.0303 0.0217 TD 0.014 Tc 0.1 Tw [(d)29(i)-11(mens)39(i)19(o)-1(n)29(a)3(l)19( D)9(e)3(l)19(a)3(un)29(ay )30(t)-11(e)3(s)39(s)9(el)19(at)19(i)-11(o)29(n w)39(i)19(t)-11(h)29( a)-27(p)29(p)29(l)-11(i)-11(c)34(at)19(i)-11(o)29(ns)39( )-30(t)19(o)-1( V)9(o)-1(r)14(ono)29(i)19( pol)19(yt)19(opes)39(,)22(\224)]TJ /F7 1 Tf -14.3333 -1.1732 TD -0.022 Tw [(C)14(o)-1(m)9(put)19(er)9( Jour)39(nal)]TJ /F5 1 Tf 7.4545 0.0217 TD 0 Tc 0 Tw ( )Tj /F3 1 Tf 0.2424 -0.0326 TD 0.015 Tc (24)Tj /F5 1 Tf 1.0303 0.0326 TD -0.023 Tw [(\()15(2)0(\))15(,)23( 167)30(\2261)30(72 \()15(198)30(1\))15(.)]TJ -11 -1.1515 TD (10.)Tj /F9 1 Tf 1.2727 -0.0217 TD 0 Tc 0 Tw ( )Tj /F5 1 Tf 1 0.0217 TD -0.004 Tc 0.057 Tw [(N)-9(.)4( W)-30(e)16(a)-15(t)-29(h)11(e)-15(rill)-29(, a)-15(n)-19(d)11( )-30(O)-9(.)4( H)-9(a)-45(s)-9(s)21(a)-15(n)-19(, \223)-15(E)-29(ffi)-29(c)16(i)-29(e)16(n)-19(t t)-29(h)11(r)-35(e)16(e)16(\226)-49(d)11(i)-29(m)-14(e)16(n)-19(s)-9(io)-19(n)11(a)-15(l )-30(g)11(r)-4(i)-29(d)11( )-30(g)-19(e)-15(n)11(e)16(ra)-15(t)-29(i)1(o)-19(n)11( u)-49(s)21(i)-29(n)-19(g)11( t)-29(h)-19(e)16( D)-40(e)16(la)-15(u)-19(n)11(a)-45(y)11( )-30(tr)-35(ia)-15(n)-19(g)11(u)-19(l)1(a)-15(t)1(i)-29(o)11(n)-19(,)4(\224)]TJ 0 -1.1818 TD 0.014 Tc -0.022 Tw [(P)25(r)14(ocee)34(di)19(ng)29( )-31(of)44( )-31(t)19(h)-1(e)34( 1)-31(s)39(t)-11( E)19(u)-1(r)14(ope)34(an C)14(F)25(D)-22( C)-16(o)29(nf)14(e)34(r)-17(enc)34(e)3(,)22( )]TJ /F3 1 Tf 20.2727 -0.0326 TD 0.015 Tc -0.023 Tw (1 \()Tj /F5 1 Tf 1.0909 0.0326 TD [(1992\))15(.)]TJ -23.6364 -1.1515 TD (11.)Tj /F9 1 Tf 1.2727 -0.0217 TD 0 Tc 0 Tw ( )Tj /F5 1 Tf 1 0.0217 TD 0.014 Tc 0.13 Tw [(R)14(.)22( B)-16(e)3(c)34(k)-1(,)22( B)-16(.)22( E)19(r)-17(dm)34(ann)29( a)-27(n)-1(d)29( R)14(.)-9( R)-16(o)29(i)19(t)-11(zs)9(c)34(h)-1(,)22( \223)-27(K)39(a)-27(s)39(kade)34( 3.)22(0 )-30(\227)-16( )-61(A)39(n)-1( )-30(ob)29(j)-11(e)3(c)34(t)19(\226or)14(i)-11(e)34(n)29(t)-11(ed)29( )-30(a)-27(d)29(ap)29(t)-11(i)19(ve )-61(f)44(i)-11(n)29(i)19(t)-11(e)34( )-61(e)34(l)-11(eme)34(n)-1(t)19( )-61(c)34(ode)34(,)22(\224)]TJ 0 -1.1515 TD -0.021 Tw [(T)-11(e)34(ch)29(ni)19(c)34(a)3(l)-11( r)-17(e)34(po)29(r)14(t)-11( T)-11(R)14( 95\2264,)22( K)9(o)29(n)29(r)14(a)-27(d)29(\226Z)19(us)9(e)34(\226)-1(Z)-11(e)3(n)29(t)19(r)14(u)-31(m)34( )-30(f)44(\374)-1(r)14( I)-17(n)-1(f)14(o)29(r)-17(m)34(at)19(i)-11(o)29(ns)9(t)19(echn)29(i)19(k,)22( B)-16(e)34(r)-17(l)19(i)19(n)-1( \()14(1995\))14(.)]TJ -2.2727 -1.1818 TD 0.015 Tc (12.)Tj /F9 1 Tf 1.2727 -0.0217 TD 0 Tc 0 Tw ( )Tj /F5 1 Tf 1 0.0217 TD -0.016 Tc 0.16 Tw [(T)-41(.)-8( )30(L)-11(.)-8( )30(T)-41(r)-16(o)-31(y)-1(,)-8( D)-21(.)-8( L)-11(.)-8( Pa)-27(g)-31(e)4(,)-39( )30(D)-21(.)-8( L)-11(.)-8( )30(a)-57(n)-31(d )30(E)-41(.)-8( )-30(M.)-8( )-32(S)-36(e)4(vi)-41(ck)-31(\226)-31(M)-6(u)-31(r)-16(a)-57(c)4(a)-27(,)-8( \223)-27(O)-52(pt)-11(i)-41(c)4(a)-27(l)-11( )-30(pr)-47(op)-31(er)-16(t)-41(i)-41(e)-27(s)9( o)-31(f)-16( )-30(nor)-47(ma)-27(l)-41( a)-27(n)-31(d )-30(di)-41(s)-21(e)4(a)-57(s)9(e)-27(d)-1( )-30(br)-47(ea)-57(s)9(t)]TJ 0 -1.1515 TD 0.013 Tc 0.01 Tw [(t)18(i)18(s)8(s)38(u)-32(es)38(:)18( P)24(r)-18(o)28(gnos)38(i)-12(s)38( f)13(o)28(r)13( op)28(t)18(i)-12(c)33(a)2(l)-12( )31(m)33(a)-28(mmo)28(gr)13(aph)28(y)-2(,)21(\224)2( )31(J)8(.)21( B)13(i)-12(o)28(m)3(ed)28(i)-12(c)33(al)18( )31(O)-23(p)28(t)-12(.)21( )]TJ /F3 1 Tf 26.7576 -0.0326 TD 0 Tc 0 Tw (3)Tj /F5 1 Tf 0.5152 0.0326 TD 0.015 Tc -0.023 Tw [(,)23( 342\226355 \()15(199)30(6\))15(.)]TJ -29.5455 -1.1515 TD (13.)Tj /F9 1 Tf 1.2727 -0.0217 TD 0 Tc 0 Tw ( )Tj /F5 1 Tf 1 0.0217 TD 0.014 Tc 0.039 Tw [( H)9(.)22( L)-11(.)22( G)9(r)14(a)-27(b)-1(e)34(r)14(,)22( Y)-22(.)22( )-31(P)25(e)3(i)19(,)22( R)-16(.)22( )-30(A)39(r)-17(ons)39(on)29(,)-9( H)9(.)22( a)-27(n)29(d R)14(.)-9( L)19(.)-9( B)14(a)3(r)14(b)-1(o)29(u)-1(r)14(,)-9( \223D)9(epe)34(nde)34(nce)34( )-30(of)44( )-61(ob)29(j)-11(e)3(c)34(t)19( )-61(s)9(e)3(ns)39(i)19(t)19(i)-11(v)29(i)-11(t)19(y)-1( )-30(and)29( )-30(r)-17(e)3(s)9(o)29(l)19(u)-1(t)19(i)-11(o)29(n)-1( )-30(on)]TJ 0 -1.1818 TD -0.005 Tc 0.028 Tw [(o)10(p)-20(ti)-30(c)15(a)-16(l )31(t)-30(h)10(i)-30(c)15(k)-20(n)-20(e)-16(s)-10(s)20( o)-20(f)25( s)-10(c)15(a)-16(t)-30(te)15(r)-36(i)0(n)-20(g)10( m)-15(e)-16(d)10(i)0(a)-16(,)3(\224)-16( A)-10(p)-20(p)10(l)0(.)-28( )31(O)-10(p)-20(t. s)20(u)-50(b)10(m)-15(itt)-30(e)-16(d)10(.)]TJ ET 116.04 151.92 380.16 -1.44 re f* endstream endobj 3 0 obj << /ProcSet [/PDF /Text ] /Font << /F3 4 0 R /F5 5 0 R /F7 6 0 R /F9 7 0 R >> /ExtGState << /GS1 8 0 R >> >> endobj 11 0 obj << /Length 19233 >> stream 1 1 1 rg /GS1 gs 21 -66 612 792 re f BT /F3 1 Tf 12 0 0 12 117.48 708.96 Tm 0 0 0 rg 0 Tc (1.)Tj /F11 1 Tf 0.76 0 TD 0 Tw ( )Tj /F3 1 Tf 0.74 0 TD 0.005 Tc [(I)14(n)1(tr)29(o)5(duc)9(tio)5(n)]TJ /F5 1 Tf 10.08 0 0 10.08 117.48 691.92 Tm 0.008 Tc 0.313 Tw [(M)16(o)32(s)16(t)0( )23(b)32(a)0(s)16(i)0(c)23( to)32( a)23(n)-16(y)56( imag)32(i)24(n)-16(g)32( me)23(t)24(h)-16(o)32(d)8( )23(is)16( )23(a)23(n)-16( )23(ap)8(p)32(r)-16(e)23(c)23(i)0(a)23(tio)32(n)8( o)32(f)31( th)-16(e)47( lim)24(i)24(t)0(s)16( o)32(f)31( s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56( an)-16(d)]TJ 0 -1.1429 TD 0.075 Tw [(ac)23(h)8(i)0(e)23(v)32(ab)32(le)23( r)-16(e)23(s)16(o)32(lu)8(tio)32(n)-16(.)20( )23( U)40(lti)24(m)24(ate)23(ly)56(, t)24(h)-16(e)23(s)16(e)23( a)23(r)-16(e)23( l)24(i)0(m)24(ite)23(d)8( b)32(y)56( th)-16(e)23( q)8(u)32(al)24(ity)56( o)8(f)31( th)-16(e)47( c)23(o)32(lle)23(c)23(t)0(e)23(d)8( d)8(ata)23(.)20( I)31(n)]TJ T* 0.194 Tw [(t)24(h)-16(e)23( c)23(a)0(s)16(e)23( o)32(f)31( s)16(imp)8(le)23( p)32(r)-16(o)32(j)24(e)23(c)23(tio)32(n)-16( i)24(mag)32(i)24(n)-16(g)32(,)-4( )23(t)24(h)-16(e)23( p)32(r)-16(o)32(p)8(e)23(r)8(tie)23(s)16( o)32(f)31( th)-16(e)47( p)8(o)32(in)8(t-)8(s)16(p)32(r)-16(e)23(ad)32( )-24(f)31(u)8(n)-16(c)23(t)24(i)0(o)32(n)8( )-24(l)24(a)23(r)-16(g)8(e)23(l)0(y)]TJ T* 0.171 Tw [(d)8(e)23(te)23(r)-16(m)24(i)24(n)-16(e)23( t)24(h)-16(e)47( s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56( a)23(n)-16(d)8( )24(r)-16(e)23(s)16(o)32(lu)8(tio)56(n)-16( )24(li)24(mi)24(ts)16(.)20( F)16(o)32(r)8( )24(mo)32(d)8(e)23(l\226)8(b)32(a)0(s)16(e)23(d)8( to)32(mo)32(g)8(r)-16(ap)32(h)8(i)0(c)23( i)24(mag)32(i)24(n)-16(g)32( )-23(o)32(f)]TJ T* 0.075 Tw [(s)16(c)23(atte)23(r)8(i)24(n)-16(g)32( )23(me)23(d)8(i)24(a,)20( s)16(i)0(g)32(n)8(if)31(ic)23(a)23(n)-16(t)24( i)24(m)0(p)32(r)-16(o)32(v)32(e)23(me)23(n)-16(t)0( )23(i)24(n)-16( b)32(o)32(t)0(h)8( q)8(u)32(a)23(n)-16(t)24(i)0(t)24(i)0(e)23(s)16( is)16( p)8(o)32(s)16(s)16(i)0(b)32(l)0(e)23(,)-4( a)23(l)0(t)24(h)-16(o)32(u)8(g)32(h)8( i)24(n)8( p)32(r)8(ac)23(tic)23(e)]TJ T* 0.337 Tw [(t)24(h)-16(ey)56( )24(ar)-16(e)47( s)16(t)24(r)-16(o)32(n)-16(g)32(ly)56( in)-16(f)31(l)0(u)8(e)47(n)-16(c)23(e)23(d)8( b)8(y)56( a c)23(o)32(mp)8(le)23(x)8( )24(r)-16(e)23(la)23(tio)32(n)-16(s)40(h)8(i)0(p)8( b)32(e)23(tw)40(e)23(e)23(n)-16( a )24(h)-16(o)32(s)16(t)0( o)32(f)31( p)8(a)23(r)8(ame)23(te)47(r)-16(s)]TJ T* 0.075 Tw [(as)16(s)16(o)32(c)23(iate)23(d)8( w)40(ith)8( t)24(h)-16(e)47( t)24(a)23(r)-16(g)8(e)23(t)0( )23(p)32(r)-16(o)32(p)8(e)23(r)-16(tie)23(s)16( \()]TJ /F7 1 Tf 15.2143 -0.052 TD [(i.)20(e)]TJ /F5 1 Tf 0.9524 0.052 TD 0.009 Tc 0.074 Tw [(.,)21( t)25(a)24(r)-15(g)9(e)24(t)25( d)9(o)33(mai)25(n)9(\))9(,)21( c)24(o)33(n)-15(d)9(i)25(tio)33(n)-15(s)41( a)24(n)9(d)9( q)33(u)9(a)24(lity)57( o)9(f)32( )-24(c)24(o)33(lle)24(c)24(t)1(e)24(d)]TJ -16.1667 -1.1429 TD 0 Tc 0.131 Tw [(da)-8(t)16(a)-8( \()]TJ /F7 1 Tf 2.3571 -0.052 TD 0.008 Tc [(i.)20(e)]TJ /F5 1 Tf 0.9762 0.052 TD 0.123 Tw [(.)20(,)20( me)23(as)16(u)32(r)-16(e)23(m)0(e)47(n)8(t d)8(o)32(m)24(a)0(i)24(n)-16(\))31(,)-4( )24(a)23(n)-16(d)32( s)16(t)24(ab)32(ility)56( a)23(n)-16(d)32( ac)23(c)23(u)8(r)8(a)0(c)23(y)56( )-24(o)32(f)31( n)-16(u)8(me)47(r)-16(i)0(c)23(a)23(l)0( )24(me)23(t)24(h)-16(o)32(d)8(s)16( u)8(s)16(e)23(d)8( )-24(f)31(o)32(r)]TJ -3.3333 -1.1429 TD -0.015 Tc 0.051 Tw [(i)-23(m)1(a)-23(g)-15(e )24(r)-39(eco)-15(v)9(e)0(r)-63(y)33( \()]TJ /F7 1 Tf 6.7619 -0.052 TD 0.01 Tc (i.e)Tj /F5 1 Tf 0.9762 0.052 TD 0.009 Tc [(.,)21( )48(a)24(n)-15(a)24(l)1(y)57(s)17(is)17( )24(d)9(o)33(main)9(\))9(.)21( )24( )48(To)33( d)9(e)24(r)9(i)1(v)33(e)24( a u)9(s)17(e)24(f)32(u)9(l)1( to)33(o)33(l)1( )24(r)-15(e)24(q)9(u)9(i)25(r)-15(e)24(s)17( s)17(u)33(it)25(ab)33(le)24( o)33(p)9(timi)25(za)24(tio)57(n)]TJ -7.7381 -1.1429 TD 0.008 Tc 0.123 Tw [(o)8(f)31( )24(th)-16(e)23(s)16(e)23( p)32(a)23(r)-16(a)23(me)23(te)23(r)-16(s)40(. )24( I)31(n)8( p)32(r)8(ac)23(tic)23(e)23(,)-4( )24(as)16(s)16(e)23(s)16(s)16(m)0(e)23(n)-16(t)24( o)32(f)31( th)-16(e)23( )24(n)-16(e)23(c)23(e)23(s)16(s)16(a)0(r)-16(y)56( tr)8(ad)8(e)23(o)32(f)8(f)31(s)16( c)23(a)0(n)-16( b)32(e)23( c)23(o)32(mp)8(lic)23(ate)23(d)]TJ T* -0.015 Tc 0.313 Tw [(b)9(e)-23(ca)-23(u)-15(s)-7(e o)-15(f)8( i)-23(n)-15(t)-23(e)0(r)-15(a)-23(ct)-23(i)-23(o)9(n)-39(s)17( am)-23(o)9(n)-39(g)9( th)-39(e)24( )-23(th)-15(r)-39(ee )-23(d)9(i)-23(f)8(f)-15(er)-39(en)-15(t)-23( )-23(p)9(a)0(r)-15(a)-23(m)-23(e)0(t)-23(e)24(r)-39( )-23(d)-15(o)9(ma)-23(in)-39(s)17( )-23(w)17(h)-39(o)9(s)-7(e )-23(p)-15(a)0(r)-39(t)1(i)-23(c)0(u)-15(l)-23(ar)-39(s)]TJ 0 -1.119 TD 0.008 Tc 0.147 Tw [(d)8(e)23(p)8(e)23(n)-16(d)8( )24(o)56(n)-16( )48(t)24(h)-16(e)23( )24(p)32(h)-16(y)56(s)16(ic)23(s)16( )24(o)8(f)31( )24(e)23(n)-16(e)23(r)-16(g)8(y)56( )24(p)8(r)-16(o)32(p)8(ag)8(a)23(tio)56(n)-16( )24(f)31(o)32(r)-16( )48(t)24(h)-16(e)23( p)32(r)-16(o)32(b)32(l)0(e)23(m)0( b)32(e)23(in)-16(g)32( s)16(t)0(u)8(d)32(ie)23(d)8(.)20( K)16(e)23(y)56( to)32( th)-16(e)23(s)16(e)]TJ 0 -1.1429 TD 0.099 Tw [(e)23(f)8(f)8(o)32(r)-16(t)0(s)16( is)40( t)24(h)-16(e)23( )24(n)-16(e)23(e)23(d)8( )24(to)32( ad)8(o)32(p)8(t )24(me)23(t)24(h)-16(o)32(d)8(o)32(l)0(o)32(g)8(ie)23(s)16( th)8(at)24( id)8(e)47(n)8(tif)8(y)56( e)23(x)8(p)8(e)23(c)23(t)0(e)23(d)8( s)-8(y)32(s)16(t)0(e)23(m)0( p)8(e)23(r)-16(f)31(o)32(r)-16(m)24(a)23(n)-16(c)23(e)23( )-24(u)32(n)-16(d)8(e)47(r)]TJ T* 0.171 Tw [(d)8(e)23(f)31(i)0(n)-16(e)23(d)8( )24(r)-16(e)23(al)24(is)16(tic)23( c)23(o)32(n)-16(d)32(it)24(io)32(n)-16(s)16(.)20( )24( W)23(e)23( b)32(e)23(lie)23(v)8(e)23( th)8(at)24( s)16(u)8(c)23(h)8( )24(r)-16(e)23(s)16(u)8(lts)40( )-23(c)23(a)23(n)-16( p)32(r)-16(o)32(v)32(i)0(d)8(e)23( )-23(a )-23(g)8(u)32(id)8(e)23( )-23(to)32( r)8(a)0(t)24(i)0(o)32(n)8(al)]TJ T* 0.075 Tw [(i)24(n)-16(s)16(t)24(r)-16(u)32(me)23(n)8(t)0( )47(d)8(e)23(v)32(e)23(l)-24(o)32(p)8(m)0(e)23(n)-16(t)24(,)-4( )23(a)23(n)-16(d)32( s)16(e)23(r)-16(v)32(e)23( as)16( )23(a b)32(a)0(s)16(i)0(s)40( o)32(f)31( co)32(mp)8(a)23(r)-16(is)16(o)32(n)8( to)32( c)23(l)0(i)24(n)8(ic)23(al)24( s)16(t)0(u)32(d)8(ie)23(s)16( a)23(n)8(d)8( )23(a)23(n)8( a)23(i)0(d)8( )23(i)24(n)]TJ T* 0.004 Tw [(te)23(s)16(t)0( v)32(alid)32(at)24(io)32(n)8(.)]TJ 2.4524 -1.1429 TD 0.409 Tw [(R)32(e)0(c)23(e)23(n)-16(tly)56( a v)32(a)0(r)8(i)0(e)23(t)0(y)56( o)8(f)31( in)-16(s)16(t)24(r)8(u)8(m)0(e)47(n)-16(t)24( c)23(o)32(n)-16(f)31(ig)8(u)32(r)-16(a)23(tio)32(n)-16(s)40( e)23(m)0(p)8(l)0(o)32(y)56(in)-16(g)8( o)32(p)8(tic)23(a)23(l)0( )24(me)23(as)16(u)32(r)-16(e)23(m)0(e)47(n)-16(t)]TJ -2.4524 -1.1429 TD -0.015 Tc 0.051 Tw [(s)-7(c)0(h)-39(e)0(m)-23(e)0(s)-7( )48(h)-39(a)-23(v)9(e)0( )24(b)9(een)-39( )24(p)9(r)-39(o)9(p)-15(o)9(s)-31(ed)-15( t)-23(o)9( in)-39(v)9(e)0(s)-7(t)-23(i)-23(g)-15(a)-23(t)-23(e)0( )24(th)-39(e b)9(r)-39(ea)-23(s)17(t)-23(. )24(E)-23(x)9(a)-23(m)-23(p)9(l)-23(e)0(s)-7( in)-39(cl)-23(u)9(d)-15(e:)-23( p)-15(l)1(an)-15(ar)-15( co)9(m)-23(p)-15(r)-39(e)0(s)-7(s)-7(i)-23(o)9(n)]TJ T* 0.004 Tc 0.103 Tw [(us)12(i)20(n)-20(g )47(a )47(ras)12(t)-4(e)43(r)-20( )24(s)12(c)19(a)19(n)4( )47(me)19(t)20(h)-20(o)28(d)4( )24(w)36(i)-4(t)20(h)-20( )47(a s)12(i)20(ngle)19( )24(de)19(te)19(c)19(t)-4(o)28(r)-20( po)28(s)12(itio)52(n)-20(e)19(d o)28(ppo)28(s)12(ite)19( a s)12(o)28(u)28(r)-20(c)19(e)19( [1],)16( a)19( s)12(i)20(mil)20(a)19(r)]TJ T* 0 Tc 0.06 Tw [(ge)15(o)24(m)-8(e)15(t)-8(r)-24(y)48( )-23(b)24(u)0(t)-8( w)32(i)-8(t)16(h)-24( )24(a)15(n)-24( )24(a)15(rra)-8(y)48( of)23( s)-16(o)24(ur)-24(c)15(e)15(s)8( [2],)12( a)15( m)-8(u)24(l)-8(t)16(i)-8(\226)0(s)8(o)24(ur)-24(c)15(e)15( pl)16(a)-8(n)0(a)15(r)0( )24(ra)-8(di)16(a)-8(l)16( )24(m)-8(e)15(a)-8(s)8(u)24(r)-24(e)15(m)-8(e)15(n)0(t)-8( )24(m)-8(e)15(t)16(h)-24(o)24(d)]TJ T* 0.008 Tc 0.123 Tw [(w)40(ith)8( [)8(3)8(])31( a)23(n)-16(d)32( w)40(i)0(t)24(h)-16(o)32(u)8(t [)31(4)8(])8( )24(a)23(n)8( ad)32(ap)8(t)24(i)0(v)32(e)23( me)23(as)16(u)32(r)-16(e)23(m)0(e)23(n)8(t )24(h)-16(e)47(ad)8(,)20( )24(a)23(n)-16(d)8( a)23( mu)32(lt)24(i\226)8(s)16(o)32(u)8(r)-16(c)23(e)23( )-24(a)23(r)-16(e)23(a)23( )-24(d)8(e)23(te)23(c)23(tio)32(n)]TJ T* 0 Tc 0.274 Tw [(m)-8(e)15(t)16(h)-24(o)24(d)0( )24(w)32(i)-8(t)16(h)-24( )48(a)-8( f)23(i)-8(xe)15(d c)15(u)0(p)24( ge)15(o)24(m)-8(e)15(t)-8(r)-24(y)48( [5].)12( A)32(n)0( a)-8(p)24(p)24(r)-24(o)24(a)-8(c)15(h)0( w)32(e)15( h)-24(a)-8(v)24(e)15( t)16(a)-8(ke)15(n t)-8(o)24( g)24(u)0(i)-8(d)0(e)15( )24(ra)-8(t)16(i)-8(o)24(n)0(a)-8(l)]TJ 0 -1.119 TD 0.179 Tw [(i)16(n)-24(s)8(t)16(r)-24(u)24(m)-8(e)15(nt)-8( )24(de)15(v)24(e)15(l)-32(o)24(pm)-8(e)15(n)-24(t)16( )24(h)-24(a)-8(s)32( b)24(e)15(e)15(n)-24( t)-8(o)24( us)8(e)15( c)15(o)24(m)-8(put)-8(e)39(r)-24( )24(m)-8(o)24(de)15(l)-8(i)16(n)-24(g)24( a)15(n)-24(d)24( )-23(s)8(i)16(m)-8(u)0(l)16(a)-8(t)16(i)-8(o)24(n)0( )-23(t)-8(e)15(c)15(hni)-8(que)15(s)8( )-23(t)-8(o)]TJ 0 -1.1429 TD 0.008 Tc 0.123 Tw [(e)23(v)32(alu)8(ate)23( )24(a)23(n)8(ato)32(m)24(i)0(c)23(ally)56( ac)23(c)23(u)8(r)8(ate)23( )24(mo)32(d)8(e)23(ls)16( o)32(f)31( h)-16(u)8(m)24(a)23(n)-16( )24(tis)16(s)16(u)8(e)23( )24(as)16( d)8(e)23(f)31(i)0(n)-16(e)23(d)32( b)8(y)56( M)16(R)32( imag)8(e)23(s)16( [)8(6)8(])31(.)20( W)23(e)]TJ T* 0.432 Tw [(h)-16(o)32(ld)32( t)24(h)8(at)24( t)24(h)8(is)16( )23(ap)8(p)32(r)-16(o)32(a)0(c)23(h)8( is)40( f)31(a)23(r)-16( )23(mo)32(r)-16(e)23( c)23(o)32(s)16(t)0(\226)8(e)23(f)8(f)8(e)23(c)23(tiv)8(e)23( t)24(h)-16(a)23(n)8( e)23(m)0(p)32(i)24(r)-16(i)0(c)23(a)23(lly)56( )-24(b)32(a)0(s)16(e)23(d)8( )-24(p)8(r)-16(o)32(t)0(o)32(t)-24(y)56(p)8(e)]TJ T* 0 Tc 0.012 Tw [(de)15(ve)15(l)-8(o)24(pm)-8(e)15(n)-24(t)-8( e)15(f)23(fo)24(r)-24(t)-8(s)8( )24(i)16(n)-24(v)24(o)24(l)-8(v)24(i)-8(n)-24(g)0( )24(t)-8(e)15(s)8(t)-8( m)-8(e)15(a)-8(s)8(u)24(r)-24(e)39(m)-8(e)15(n)0(t)-8(s)8( pe)39(r)-24(f)23(o)24(r)-24(m)-8(e)15(d o)48(n)-24( v)24(o)24(l)-8(unt)-8(e)15(e)15(r)-24(s)8(.)]TJ 2.4524 -1.1429 TD 0.008 Tc 0.075 Tw [(A)16(s)16( a )23(p)32(r)-16(e)23(c)23(u)8(r)-16(s)16(o)32(r)8( to)32( s)16(y)56(s)16(t)0(e)23(matic)23(ally)56( d)8(e)23(f)31(i)0(n)-16(i)24(n)-16(g)32( t)24(h)-16(e)47( d)8(e)23(p)8(e)23(n)-16(d)8(e)47(n)-16(c)23(y)56( th)-16(at )23(e)23(a)0(c)47(h)8( o)32(f)31( th)-16(e)23(s)16(e)23( )-24(p)8(a)23(r)8(ame)23(te)47(r)]TJ -2.4524 -1.1429 TD 0 Tc 0.012 Tw [(do)24(m)-8(a)-8(i)16(n)-24(s)8( )24(ha)-8(s)8( o)48(n)-24( e)15(xpe)15(c)15(t)-8(e)15(d)0( i)16(m)-8(a)15(g)0(e)15( qu)24(a)-8(l)-8(i)16(t)-8(y)48(,)-12( )-24(i)16(n)-24( t)16(h)-24(i)-8(s)32( r)-24(e)15(po)24(r)-24(t)16( )-24(w)32(e)15( )-24(ha)-8(v)24(e)15( )-24(e)15(xpl)-8(o)24(r)-24(e)15(d)0( )-24(t)16(h)-24(e)15( de)15(pe)15(n)-24(d)0(e)39(n)-24(c)15(i)-8(e)15(s)8( )-24(t)16(h)0(a)-8(t)]TJ T* 0.008 Tc 0.052 Tw [(tw)40(o)32( )-23(o)8(f)31( t)24(h)-16(e)23(s)16(e)23( d)8(o)32(mai)24(n)-16(s)16(,)20( \()]TJ /F7 1 Tf 9.4762 -0.052 TD [(i.)20(e.)]TJ /F5 1 Tf 1.2143 0.052 TD 0.009 Tc 0.074 Tw [(, )23(ta)24(r)9(g)9(e)24(t p)33(r)-15(o)33(p)9(e)24(r)9(tie)24(s)17( )23(a)24(n)-15(d)33( me)24(as)17(u)33(r)-15(e)24(m)1(e)24(n)9(t)25( te)24(c)48(h)9(n)-15(i)1(q)33(u)9(e)24(\))9(, )23(h)9(a)1(v)33(e)24( o)33(n)-15( )23(me)24(as)17(u)33(r)-15(e)24(s)]TJ -10.6905 -1.1429 TD 0.008 Tc 0.171 Tw [(o)8(f)31( s)16(e)23(n)-16(s)16(itiv)32(ity)56( a)23(n)-16(d)32( e)23(d)8(g)8(e)23( )24(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( to)32( a)23(n)8( i)24(n)-16(c)47(l)0(u)8(d)8(e)23(d)8( )-23(o)32(b)32(j)0(e)23(c)23(t)0( )-23(\()8(s)16(imu)8(l)24(a)0(t)24(i)24(n)-16(g)32( )-23(a)23( )-23(tu)32(mo)32(r)-16(\))31( )-23(lo)32(c)23(ate)23(d)8( i)24(n)-16( a)]TJ T* 0 Tc 0.298 Tw [(M)8(R)24(I\226de)15(r)-24(i)-8(v)24(e)15(d )24(b)24(r)-24(e)15(a)-8(s)8(t)-8( )48(m)-8(a)15(p )24(a)-8(s)8( de)15(t)-8(e)39(r)-24(m)16(i)16(n)-24(e)15(d)0( b)24(y)48( a)-8( )]TJ /F7 1 Tf 19.8333 -0.052 TD 0.008 Tc 0.29 Tw [(s)16(i)0(m)16(p)8(le)23( p)8(r)16(o)32(j)0(e)23(cti)24(o)8(n)]TJ /F5 1 Tf 7.2143 0.052 TD 0.009 Tc 0.289 Tw [(.)21( )24( S)17(p)9(e)24(c)24(i)1(f)32(i)1(c)24(ally)57(, w)17(e)24( h)-15(a)1(v)33(e)]TJ -27.0476 -1.1429 TD -0.015 Tc 0.075 Tw [(ex)-15(a)-23(m)-23(i)1(n)-39(e)0(d)9( th)-39(e )24(in)-39(t)-23(e)24(r)-39(-)-15(d)-15(e)0(p)-15(e)24(n)-39(d)-15(en)-39(ci)-23(es)-7( th)-39(at)-23( m)-23(e)0(a)-23(s)-7(u)9(r)-39(em)-23(e)24(n)-39(t )-23(p)9(a)0(r)-39(a)0(m)-23(e)0(t)-23(e)0(r)-39(s)17( )-23(\()]TJ /F7 1 Tf 25.9048 -0.052 TD [(e.)-27(g)]TJ /F5 1 Tf 1.1905 0.052 TD -0.024 Tc 0.107 Tw [(.)-12(,)-12( vi)-32(e)-9(w)8( a)-32(n)-48(gl)-32(e)-9(,)-36( w)8(a)-32(ve)-9(l)-32(e)-9(n)-48(g)-24(t)-8(h)]TJ -27.0952 -1.1429 TD 0.008 Tc 0.075 Tw [(a)23(n)-16(d)8( s)16(o)32(u)32(r)-16(c)23(e)23( lo)32(c)23(atio)32(n)-16(\))31( a)23(n)8(d)8( )23(ta)23(r)-16(g)8(e)23(t)24( p)32(a)23(r)-16(a)23(me)23(te)23(r)-16(s)40( \()]TJ /F7 1 Tf 17.8571 -0.052 TD -0.015 Tc [(e.)-27(g)]TJ /F5 1 Tf 1.1667 0.052 TD 0.009 Tc 0.098 Tw [(.,)21( u)9(s)17(e)24( o)33(f)32( c)24(o)33(n)-15(t)1(r)-15(a)24(s)17(t)25( ag)9(e)48(n)-15(ts)41(, )24(ta)24(r)9(g)9(e)24(t g)9(e)24(o)33(m)1(e)24(t)25(r)-15(y)57( an)-15(d)]TJ -19.0238 -1.1429 TD -0.024 Tc 0.369 Tw [(s)-16(i)-32(z)-32(e)-9(,)-36( )24(ba)-32(c)-9(k)-24(gr)-48(oun)-48(d)-24( c)-9(o)0(n)-24(t)-8(r)-48(a)-32(s)-16(t)-8(,)-12( i)-8(n)-48(c)-9(l)-32(u)-24(s)8(i)-32(o)0(n)-48( c)-9(o)0(n)-24(t)-8(r)-48(a)-32(s)8(t)-32( )24(a)-9(n)-48(d s)-16(t)-8(r)-48(u)-24(c)-9(t)-32(ur)-24(a)-32(l)-8( )24(h)-48(e)-9(t)-32(e)15(r)-48(o)0(g)-24(e)-9(n)-48(e)-9(i)-32(t)-32(y)24(\))-24( h)-24(a)-32(ve)-9( on)-48( t)-8(h)-48(e)]TJ 0 -1.119 TD 0.008 Tc 0.171 Tw [(s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56( an)-16(d)32( e)23(d)8(g)8(e)23( r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( )-23(f)31(o)32(r)-16( )-23(a)23( )-23(d)8(e)23(f)31(i)0(n)-16(e)23(d)8( r)-16(e)23(g)32(i)0(o)32(n)-16(-)8(o)32(f)31(-)8(in)8(te)23(r)-16(e)23(s)16(t)24( )-23(\()8(R)32(O)16(I)8(\))8(.)-4( )-23(W)23(e)23( r)-16(e)23(c)23(o)32(g)8(n)-16(ize)23( t)24(h)-16(a)23(t)]TJ 0 -1.1429 TD 0.266 Tw [(me)23(as)16(u)32(r)-16(e)23(s)16( o)32(f)31( r)-16(e)23(s)16(o)32(lu)8(tio)32(n)-16( )24(d)8(e)23(r)8(i)0(v)32(e)23(d)8( f)31(r)-16(o)32(m)0( p)32(r)-16(o)32(j)24(e)23(c)23(tio)32(n)-16( d)8(a)0(t)24(a)23( d)8(o)32( )24(n)-16(o)32(t )-24(c)23(o)32(in)-16(c)23(i)0(d)8(e)23( )-24(o)56(n)-16( a 1)8(:)0(1)32( )-24(b)32(a)0(s)16(i)0(s)16( )-24(to)]TJ T* 0.052 Tw [(v)32(a)0(r)-16(i)24(at)24(io)32(n)-16(s)16( )24(i)24(n)-16( )24(r)-16(e)23(s)16(o)32(lu)8(t)24(i)0(o)32(n)-16( o)32(b)32(tai)24(n)-16(e)23(d)32( f)31(r)-16(o)32(m)0( )24(im)24(ag)8(e)23( )24(r)-16(e)23(c)23(o)32(n)-16(s)16(t)24(r)-16(u)8(c)23(tio)56(n)-16(.)20( T)24(h)-16(e)47( l)24(atte)47(r)8( is)16( )24(d)8(e)23(p)8(e)23(n)-16(d)8(e)47(n)-16(t)24( )-23(o)32(n)8( )-23(m)24(a)23(n)-16(y)]TJ T* 0.009 Tc 0.098 Tw [(f)32(a)1(c)24(t)1(o)33(r)-15(s)17( i)25(n)-15(c)24(l)1(u)9(d)33(i)25(n)-15(g)9( v)33(i)1(e)24(w)41( a)24(n)-15(g)9(l)1(e)24(,)21( s)17(e)24(n)-15(s)41(it)25(iv)33(ity)57( to)33( ill-)9(c)24(o)33(n)-15(d)9(i)25(tio)57(n)-15(i)25(n)-15(g)33(, c)24(o)33(mp)9(u)33(tat)25(io)33(n)9(a)1(l)25( e)24(f)32(f)9(o)33(r)-15(t)1(, )24(g)33(r)-15(id)33( s)17(c)24(ale)24(,)]TJ /F7 1 Tf 0 -1.1949 TD 0.008 Tc [(etc)23(.)]TJ /F5 1 Tf 1.4048 0.052 TD 0.171 Tw [( )24( )24(N)16(e)23(v)32(e)23(r)-16(t)24(h)-16(e)23(le)23(s)16(s)16(,)-4( )48(it)24( )24(is)16( )24(f)55(r)-16(e)23(q)8(u)8(e)23(n)8(tly)56( th)-16(e)47( c)23(a)0(s)16(e)23( t)24(h)8(at)24( c)23(o)32(n)-16(d)8(it)24(io)32(n)-16(s)40( t)24(h)8(at)24( d)8(e)23(g)32(r)-16(ad)8(e)23( s)40(h)8(a)23(r)-16(p)32(n)-16(e)23(s)16(s)16( i)24(n)8( e)23(d)8(g)8(e)]TJ -1.4048 -1.1429 TD 0.313 Tw [(s)16(p)8(r)-16(e)23(ad)32( f)31(u)8(n)-16(c)23(t)24(i)0(o)32(n)-16(s)16( s)16(e)23(e)23(n)8( i)24(n)8( p)32(r)-16(o)32(j)24(e)23(c)23(tio)32(n)-16( d)32(ata)23( )23(als)16(o)32( d)8(e)23(g)8(r)8(a)0(d)8(e)23( )23(t)24(h)-16(e)23( )-24(ac)47(h)8(i)0(e)23(v)32(ab)32(le)23( )-24(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)-16( i)24(n)8( )-24(t)24(h)-16(e)]TJ T* 0.266 Tw [(c)23(o)32(r)-16(r)-16(e)23(s)16(p)8(o)32(n)-16(d)8(i)24(n)8(g)8( )24(im)24(ag)8(e)23( d)32(a)0(t)24(a)0(.)20( )24(I)8(t)24( f)31(o)32(llo)8(w)40(s)16( th)-16(a)23(t)0( s)16(p)8(e)23(c)23(i)0(f)31(i)0(c)23(atio)32(n)8( o)32(f)31( c)23(o)32(n)-16(d)8(itio)56(n)-16(s)16( t)24(h)8(at)24( )-24(o)32(p)8(ti)24(mi)24(ze)23( )-24(t)24(h)-16(e)]TJ T* 0.147 Tw [(me)23(as)16(u)32(r)-16(e)23(m)0(e)23(n)8(t )24(s)16(e)47(n)-16(s)16(i)24(tiv)32(ity)56( )24(an)8(d)8( e)23(d)8(g)8(e)23( )24(r)-16(e)23(s)16(o)32(lu)8(tio)56(n)-16( s)40(h)-16(o)32(u)8(ld)32( a)23(llo)32(w)40( f)8(o)32(r)-16( )24(r)-16(e)23(c)23(o)8(v)32(e)23(r)-40(y)56( o)8(f)31( imp)32(r)-16(o)32(v)32(e)23(d)8( imag)8(e)]TJ T* 0 Tc [(qua)-8(l)16(i)-8(t)-8(y)48(.)]TJ 2.4524 -1.1429 TD 0.008 Tc 0.29 Tw [(O)16(u)8(r)8( s)16(t)0(u)8(d)8(y)56( is)16( d)8(i)0(v)32(i)0(d)8(e)23(d)32( i)24(n)8(to)32( tw)40(o)32( p)8(a)0(r)8(t)0(s)16(:)0( e)23(x)8(p)32(l)0(o)32(r)8(atio)56(n)-16( o)32(f)31( h)-16(o)32(mo)32(g)8(e)23(n)-16(e)23(o)32(u)8(s)16( )-23(mo)32(d)8(e)23(ls)16( )-23(w)40(i)0(t)24(h)-16( a)]TJ -2.4524 -1.1429 TD 0.242 Tw [(c)23(e)23(n)-16(te)23(r)-16(e)23(d)32( i)24(n)-16(c)23(l)0(u)8(s)16(io)56(n)-16( s)40(imu)32(la)23(ti)24(n)-16(g)32( )24(a )24(tu)8(mo)56(r)-16(,)20( a)23(n)8(d)8( e)23(x)8(a)23(m)0(i)24(n)8(a)23(tio)32(n)8( o)32(f)31( an)-16(a)23(t)0(o)32(m)24(ic)23(ally)56( ac)23(c)23(u)8(r)8(ate)23( )-24(o)32(p)8(tic)23(a)23(l)]TJ 0 -1.119 TD -0.01 Tc 0.093 Tw [(\()-10(AAO\))-10( )23(b)14(r)-34(e)5(a)-18(st)6( )23(m)-18(o)14(d)-10(e)5(l)-18(s)-2(, )23(d)-10(e)5(f)13(i)-18(n)-34(e)5(d)-10( b)14(y)38( M)-26(R)14(I)-10( d)-10(a)-18(t)6(a)-18(, c)5(o)14(n)-34(t)6(a)-18(i)6(n)-10(i)6(n)-34(g)14( a)5( c)5(e)5(n)-34(t)-18(e)29(r)-34(e)5(d)-10( \223)5(t)-18(u)14(m)-18(o)14(r)-10(.)-22(\224)-18( )23( W)5(e)5( )23(i)6(n)-34(c)5(l)-18(u)-10(d)-10(e)5( )23(t)6(h)-34(e)]TJ 0 -1.1429 TD -0.015 Tc 0.098 Tw [(h)-39(o)9(m)-23(o)9(g)-15(e)0(n)-39(e)0(o)9(u)-15(s)-7( )23(m)-23(o)9(d)-15(e)0(l)-23( )23(p)9(r)-39(im)-23(ar)-15(i)-23(l)-23(y)33( )23(t)-23(o)9( )23(d)-15(i)-23(f)8(f)8(e)0(r)-39(e)0(n)-39(t)-23(ia)-23(t)-23(e)0( )47(th)-39(e )23(in)-39(f)8(l)-23(u)-15(e)0(n)-39(ce o)9(f)8( g)-15(e)-23(o)9(m)-23(et)-23(r)-39(y)33( f)8(a)-23(ct)-23(o)9(r)-39(s)-7( f)8(r)-39(o)9(m)-23( ef)-15(f)8(e)-23(ct)-23(s)]TJ T* 0.008 Tc 0.075 Tw [(o)8(f)31( )23(in)8(te)47(r)8(n)-16(a)23(l)0( )23(c)23(o)32(n)8(t)24(r)-16(a)0(s)16(t)24( f)31(e)23(atu)32(r)-16(e)23(s)16( o)32(n)8( t)24(h)-16(e)23( )23(me)23(as)16(u)32(r)-16(e)23(d)8( )23(r)-16(e)23(s)16(p)8(o)32(n)-16(s)16(e)23(.)20( I)31(t)0(s)16( s)16(i)0(m)24(p)32(lic)23(ity)56( als)16(o)32( f)31(a)0(c)23(ilit)24(ate)23(s)16( f)31(o)32(c)23(u)8(s)16(e)23(d)]TJ T* 0.218 Tw [(lab)32(o)32(r)-16(ato)56(r)-16(y)56( )24(in)-16(v)32(e)23(s)16(tig)8(at)24(io)32(n)-16(s)40( )24(o)32(n)-16( )24(p)32(h)-16(a)23(n)8(to)32(ms)16( f)31(o)32(r)-16( t)24(h)-16(e)47( p)8(u)32(r)-16(p)8(o)32(s)16(e)23( o)32(f)31( )-24(v)32(e)23(r)-16(i)0(f)8(y)56(in)-16(g)8( p)8(o)32(te)47(n)-16(t)0(i)24(a)0(l)24(l)0(y)56( in)8(te)23(r)-16(e)23(s)16(t)0(i)24(n)8(g)]TJ T* -0.015 Tc 0.027 Tw [(s)-31(y)33(s)-7(t)-23(em)-23( p)-15(e)0(r)-39(f)8(o)9(r)-39(m)-23(a)0(n)-39(ce f)8(e)0(a)-23(t)-23(u)9(r)-39(e)0(s)-7(.)]TJ ET endstream endobj 12 0 obj << /ProcSet [/PDF /Text ] /Font << /F3 4 0 R /F5 5 0 R /F7 6 0 R /F11 13 0 R >> /ExtGState << /GS1 8 0 R >> >> endobj 14 0 obj << /Type /XObject /Subtype /Image /Name /Im1 /Width 525 /Height 569 /BitsPerComponent 4 /ColorSpace 15 0 R /Length 27148 /Filter /FlateDecode >> stream Hm:D[!܅$(y0;?,t$lŒ=ݾ7777777777777777777777a777777ϗ_0C߁!oFm f?y#x71dƣO|0_°"}0}88Xj* SQ}1}|e Qdq}`Ű*_Mj tuhJm)!o*C1 " !B&ꗆwc ]1)>&o4z cmbyT~ǰ:I)eneaU\~Uc*; Tm|*V}$6~Ic\kW` cX^~8/lkoD4:ہ[+Gc;NJ +_)M( |e9]2:; 1l+SiPvXu@Qa$qn72 [wq0u3I)~D霧e]<ebګ3ý ^N d} zO5K]Ξ1b?{ afJPKo4tW`,7(m:G>ճeTRL4fa=8`@_a*"(xˇDÜ0'I8UQ.%\383E8%1F Vg]oT(7MB;NRic9UlIY8퓾\m)}q6Ev֎0AP3ͥ3" f^W! bz > #xm`¸y?S1lotdd bײ$ƀ}T .`RaDJf9U Чm=avcɨs=Ъ)䮫kL 6׻'3;Jp ć߳ܶJL)-pm܏p NE)hтY/߁AH ;o$.-44YnD:f 8`h[Z)#YSQqw`fZ!Ԝ*% R-FR];1/c +ٱ6Xc)/L-{fCQ4&mɯ 2G%`*k8P#M 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)-24(w)41(a)1(s)17( )-24(s)17(e)24(le)24(c)24(t)1(e)24(d)]TJ T* -0.015 Tc 0.122 Tw [(b)9(e)-23(ca)-23(u)-15(s)-7(e i)-23(t)-23( )24(r)-39(e)0(p)9(r)-39(es)-7(en)-15(t)-23(s)-7( th)-39(e)24( )24(r)-39(e)0(g)-15(i)-23(o)9(n)-15( m)-23(o)9(s)-7(t)-23( d)9(i)-23(f)8(f)8(i)-23(cu)-15(l)-23(t)-23( t)-23(o)9( d)-15(e)0(t)-23(ect)-23(. )24(Th)-39(e ex)-15(t)-23(e)24(n)-39(d)-15(ed)-15( )24(r)-39(e)0(g)-15(i)-23(o)33(n)-39( w)17(a)-23(s)-7( a)-23(s)-7(s)-7(i)-23(g)9(n)-39(ed)]TJ T* 0.009 Tc 0.027 Tw [(c)24(o)9(ef)9(f)32(i)1(c)24(i)1(e)24(n)-15(ts)17( )24(c)24(o)33(r)9(r)-15(e)24(s)17(p)9(o)33(n)-15(d)33(i)25(n)-15(g)33( )24(to)33( )24(ad)33(ip)9(o)33(s)17(e)24(.)-3( )24( )48(T)25(h)-15(e)24( s)17(e)24(g)9(m)1(e)48(n)-15(te)24(d)9( )24(im)25(ag)9(e)24( s)17(e)48(r)-15(v)33(e)24(d)9( as)17( t)25(h)-15(e)48( i)25(n)-15(p)33(u)9(t)25( f)32(ile)24( f)32(o)33(r)-15( F)17(E)1(M)]TJ T* [(me)24(s)17(h)9( )24(g)9(e)24(n)-15(e)48(r)9(atio)57(n)-15(.)21( )48( )24(T)25(h)-15(e)24( )24(me)24(s)17(h)9( g)9(e)48(n)-15(e)48(r)-15(a)1(t)25(i)1(o)33(n)9( c)24(o)33(d)9(e)24(, als)17(o)33( p)33(r)-15(o)33(v)33(i)1(d)9(e)24(d)9( b)33(y)33( C)9(.)-3( J)17(o)33(h)9(n)-15(s)17(o)33(n)9(,)-3( u)9(s)17(e)24(s)17( t)25(h)-15(e)48( D)17(e)24(lau)33(n)9(a)1(y)]TJ T* 0.005 Tc 0.126 Tw [(te)20(s)13(s)13(e)20(llatio)53(n)-19( )48(algo)53(r)-19(it)21(hm)21( )24(o)29(r)-19(i)21(g)5(i)21(n)5(al)21(ly)53( )24(pr)-19(o)29(p)5(o)29(s)-11(e)20(d)5( by)53( W)20(ats)13(o)29(n)-19( [9] )24(a)20(n)-19(d )24(l)21(ate)44(r)-19( e)20(x)29(te)20(n)-19(d)5(e)20(d)29( by)53( W)20(e)20(ath)-19(e)44(r)5(h)-19(i)21(ll)]TJ T* 0 Tc ([10].)Tj 3.5714 -1.1429 TD -0.015 Tc 0.075 Tw [(Th)-39(e )24(n)-39(u)9(m)-23(b)9(er)-39( o)9(f)8( p)-15(o)9(i)-23(n)-39(t)-23(s)17( an)-15(d)-15( el)-23(em)-23(e)24(n)-39(t)-23(s)17( o)9(n)-15( th)-39(e )24(m)-23(e)0(s)-7(h)-15( u)-15(s)-7(ed)-15( )24(in)-39( )24(th)-39(e )-23(d)-15(i)-23(f)8(f)8(e)0(r)-39(e)0(n)-15(t)-23( m)-23(o)9(d)-15(e)0(l)-23(s)-7( )-23(v)9(a)-23(r)-15(i)-23(ed)]TJ -3.5714 -1.1429 TD 0.009 Tc 0.003 Tw [(w)41(ith)9( b)33(r)-15(e)24(a)1(s)17(t)25( s)17(ize)24(.)21( )24( F)17(o)33(r)-15( s)41(m)1(a)24(l)1(l)25( d)9(i)25(ame)24(te)48(r)-15(s)17(,)21( t)25(h)-15(e)48( )24(n)-15(u)33(mb)33(e)24(r)-15( o)33(f)32( th)-15(e)24( )24(p)9(o)33(in)-15(t)25(s)17( a)24(n)-15(d)33( )-24(e)24(l)1(e)24(m)1(e)24(n)9(ts)17( )-24(w)41(a)1(s)17( )-24(o)33(n)9( )-24(t)25(h)-15(e)48( )-24(o)33(r)-15(d)9(e)48(r)]TJ T* -0.015 Tc 0.075 Tw [(o)-15(f)8( )24(1)-15(,)-27(5)-15(0)-15(0)9( )24(an)-15(d)-15( 3)9(,)-27(0)-15(0)-15(0)9(, )24(r)-39(e)0(s)-7(p)-15(ect)-23(i)-23(v)9(el)-47(y)33(.)-27( F)-7(o)9(r)-39( lar)-39(g)-15(e d)9(i)-23(am)-23(et)-23(er)-39(s)17(,)-27( )24(th)-39(es)-7(e v)9(a)-23(l)-23(u)-15(es)-7( ar)-39(e )24(in)-39(cr)-39(ea)-23(s)-7(e)0(d)9( b)-15(y)33( a)-23(s)-7( m)-23(u)-15(c)24(h)]TJ T* 0.009 Tc 0.003 Tw [(as)17( a)24( f)32(a)1(c)24(t)1(o)33(r)-15( o)33(f)32( 1)9(5)9(.)21( A)41(n)9( )24(ad)9(ap)33(tiv)33(e)24( u)33(n)-15(if)32(o)33(r)-15(m)25( r)-15(e)24(f)32(i)1(n)-15(e)24(me)48(n)-15(t)25( me)24(t)25(h)-15(o)33(d)9( )-24(w)41(a)1(s)17( )-24(u)9(s)17(e)24(d)9( )-24(to)33( )-24(i)25(m)1(p)33(r)-15(o)33(v)33(e)24( )-24(th)-15(e)24( )-24(e)24(f)32(f)32(i)1(c)24(i)1(e)24(n)-15(cy)]TJ 0 -1.119 TD 0.005 Tc 0.197 Tw [(of)28( th)-19(e)44( F)13(E)-3(M)13( c)44(alc)20(ul)21(atio)53(n)-19( f)28(o)29(r)-19( )23(la)20(rge)20(\226dia)20(m)-3(e)20(t)-3(e)44(r)-19( )23(maps)37( [11])28(.)17( I)28(t)-3( )23(is)13( w)37(o)29(r)-19(t)21(h)-19( )23(n)-19(o)29(t)21(i)21(n)-19(g)29( t)21(h)5(at)21( w)37(h)-19(e)20(r)-19(e)20(a)-3(s)37( )-24(a)]TJ 0 -1.1429 TD -0.015 Tc 0.146 Tw [(v)9(a)-23(r)-39(i)-23(et)-23(y)33( o)-15(f)8( b)9(r)-39(ea)-23(s)-7(t)-23( )24(m)-23(a)-23(p)-15(s)17( )24(h)-39(a)-23(v)9(e)0( b)9(een)-39( ex)-15(a)-23(min)-39(ed)-15(, )24(h)-39(e)0(r)-39(e)24( w)17(e)0( p)-15(r)-39(es)-7(en)-39(t r)-15(e)0(s)-7(u)-15(l)-23(t)-23(s)17( o)9(n)-15( a )-24(s)-7(i)1(n)-39(g)9(l)-23(e)0( )-24(M)-7(R)9(I)-15( )-24(ma)-23(p)9(.)]TJ T* 0.008 Tc 0.313 Tw [(T)24(h)-16(u)8(s)16(,)20( )23(t)24(h)-16(e)47( )23(i)24(n)8(te)23(r)8(n)8(a)0(l)24( s)16(t)24(r)-16(u)8(c)23(t)24(u)32(r)-16(a)23(l)0( c)23(o)32(n)-16(f)31(ig)8(u)32(r)8(atio)56(n)-16( o)32(f)31( t)24(h)-16(e)23( b)32(a)0(c)23(k)8(g)32(r)-16(o)32(u)8(n)-16(d)32( t)24(i)0(s)16(s)16(u)8(e)23( is)16( )23(id)8(e)47(n)-16(tic)23(a)23(l)0( f)31(o)32(r)-16( )23(al)24(l)]TJ T* 0 Tc 0.012 Tw [(b)24(r)-24(e)15(a)-8(s)8(t)-8(/)-8(t)16(um)-8(o)24(r)0( c)15(o)24(m)-8(p)0(o)24(s)8(i)-8(t)-8(e)15( ge)15(o)24(m)-8(e)15(t)-8(r)-24(i)-8(e)15(s)8( e)15(xpl)-8(o)48(r)-24(e)15(d)0(.)12( W)15(e)15( do)24( t)16(h)0(i)-8(s)8( f)23(o)24(r)-24( t)16(h)-24(e)39( pu)24(rpo)24(s)8(e)15( of)23( di)-8(ff)23(e)15(r)-24(e)15(n)-24(t)16(i)-8(a)15(t)-8(i)16(n)-24(g)24( )-24(t)16(h)-24(e)]TJ T* 0.036 Tw [(i)16(n)-24(f)23(l)-8(ue)15(n)-24(c)15(e)15( )24(t)16(h)0(a)-8(t)16( )24(v)24(a)15(r)-24(i)-8(a)15(t)-8(i)-8(o)48(n)-24(s)8( i)16(n)0( b)24(a)-8(c)15(k)0(g)24(r)-24(o)24(und/)-8(t)16(u)0(m)-8(o)24(r 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p)24(r)-24(o)24(c)15(e)15(s)8(s)8(.)-12( F)8(o)24(r)-24( )24(a)]TJ 0 -1.2381 TD [(do)24(m)-8(a)-8(i)16(n )]TJ /F12 1 Tf 3.5 -0.0477 TD 0 Tw (W)Tj /F5 1 Tf 0.7857 0.0477 TD -0.024 Tc 0.298 Tw [( h)-24(a)-32(vi)-8(n)-48(g)-24( a)-9( )-24(bou)-24(n)-48(d)-24(a)-9(r)-48(y)24( )]TJ /F12 1 Tf 9.6667 -0.0477 TD 0 Tc 0 Tw (W)Tj -0.5 0 TD (\266)Tj /F5 1 Tf 1.5238 0.0477 TD -0.015 Tc 0.313 Tw [( an)-39(d)9( a D)-7(C)9( p)-15(o)9(in)-39(t s)-7(o)9(u)-15(r)-39(ce,)-27( th)-15(i)-23(s)-7( i)-23(s)-7( )-23(r)-15(e)0(p)9(r)-39(es)-7(en)-39(t)-23(e)0(d)9( )-23(b)-15(y)33( )-23(t)-23(h)-39(e)]TJ -14.9762 -1.1905 TD 0 Tc [(e)15(xpr)-24(e)15(s)8(s)8(i)-8(o)24(n)-24(:)]TJ /F12 1 Tf 11.28 0 0 14.16 244.2 648.48 Tm 3.88 Tc ([])Tj /F5 1 Tf 10.08 0 0 10.08 255.72 649.92 Tm 0.477 Tc [(\(\))-761(\(\))-1785(\(\))-71(\(\))-3857(\))477(,)]TJ /F7 1 Tf 6 0 0 6 309.72 647.105 Tm 0 Tc 0 Tw (a)Tj 10.08 0 0 10.08 248.28 649.396 Tm 1.873 Tc [(Du)-2698(u)]TJ ET q 1 i 288.36 647.28 147.6 12.24 re W n BT /F12 1 Tf 10.08 0 2.143 10.08 303.72 649.44 Tm 0 Tc (m)Tj ET Q BT /F12 1 Tf 10.08 0 2.143 10.08 358.2 649.44 Tm 0 Tc (d)Tj 10.08 0 0 10.08 232.44 649.44 Tm 0.12 Tc [(\321\327)-2249(\321)-2048(-)-4164(=)-117(-)-5760(\316W)]TJ /F3 1 Tf 6 0 0 6 382.68 647.28 Tm 0 Tc (s)Tj 10.08 0 0 10.08 259.08 649.526 Tm [(r)-1937(r)-2961(r)-1246(r)-2556(\(r)-175(-)-143(r)-2770(r)]TJ /F5 1 Tf 22.2143 0.0391 TD (\(1\))Tj -36.2619 -2.0714 TD -0.015 Tc [(w)17(h)-39(er)-39(e )]TJ /F7 1 Tf 2.6905 -0.052 TD 0 Tc (u)Tj /F5 1 Tf 0.5 0.052 TD (\()Tj /F3 1 Tf 0.3095 -0.0391 TD (r)Tj /F5 1 Tf 0.4524 0.0391 TD 0.009 Tc 0.003 Tw [(\))9( )24(is)17( )24(t)25(h)-15(e)24( p)33(h)-15(o)33(t)1(o)33(n)9( d)9(e)48(n)-15(s)17(ity)57( at )24(p)9(o)33(s)17(itio)33(n)9( )]TJ /F3 1 Tf 13.4762 -0.0391 TD 0 Tc 0 Tw (r)Tj /F5 1 Tf 0.4286 0.0391 TD 0.012 Tc (, )Tj /F3 1 Tf 0.5 -0.0391 TD 0 Tc (r)Tj 6.48 0 0 6.48 307.08 627.158 Tm (s)Tj /F5 1 Tf 10.08 0 0 10.08 309.48 629.04 Tm 0.009 Tc 0.003 Tw [( is)41( t)25(h)-15(e)24( )24(p)9(o)33(s)17(itio)33(n)9( o)33(f)32( th)-15(e)24( )24(p)9(o)33(in)9(t s)17(o)33(u)33(r)-15(c)24(e)24(,)-3( a)24(n)9(d)9( )]TJ /F7 1 Tf 15.6667 -0.052 TD 0 Tc 0 Tw (D)Tj /F5 1 Tf 0.7143 0.052 TD (\()Tj /F3 1 Tf 0.3333 -0.0391 TD (r)Tj /F5 1 Tf 0.4524 0.0391 TD -0.023 Tc 0.011 Tw [(\) i)-31(s)]TJ -36.2143 -1.1429 TD 0.005 Tc 0.697 Tw [(t)21(h)-19(e)20( )23(po)29(s)13(itio)29(n\226de)20(pe)20(n)-19(d)5(e)44(n)-19(t)21( d)29(i)-3(f)28(f)28(u)5(s)13(i)-27(o)29(n)-19( c)20(o)29(ef)28(f)28(i)-3(c)20(i)-27(e)20(n)-19(t)21(,)-7( w)37(h)5(ic)20(h is)37( )23(r)-19(e)20(la)20(te)20(d to)29( )23(t)21(h)-19(e)20( ab)29(s)13(o)29(r)-19(p)5(t)21(i)-3(o)29(n)]TJ 0 -1.6429 TD -0.015 Tc [(co)-15(e)-23(f)-15(f)8(i)-23(ci)-23(en)-39(t)-1237(\()-492(\))]TJ /F7 1 Tf 6 0 0 6 168.36 597.905 Tm 0 Tc 0 Tw (a)Tj ET q 1 i 160.2 598.32 25.92 12.24 re W n BT /F12 1 Tf 10.08 0 2.143 10.08 162.12 600.48 Tm (m)Tj ET Q BT /F3 1 Tf 10.08 0 0 10.08 176.04 600.566 Tm (r)Tj /F5 1 Tf 1 0.0391 TD -0.015 Tc 0.027 Tw [(an)-39(d)-15( )24(r)-39(e)0(d)-15(u)-15(ced)-15( s)-7(c)0(a)-23(t)1(t)-23(e)0(r)-15(i)1(n)-39(g)9( co)9(e)-23(f)-15(f)8(i)-23(ci)-23(en)-39(t)-23( )-1381(\()-492(\))]TJ /F7 1 Tf 6 0 0 6 332.04 597.905 Tm 0 Tc 0 Tw (s)Tj ET q 1 i 323.88 598.32 28.08 12.24 re W n BT /F12 1 Tf 10.08 0 2.143 10.08 325.8 600.48 Tm (m)Tj ET Q BT /F12 1 Tf 10.08 0 0 10.08 334.44 602.64 Tm (\242)Tj /F3 1 Tf 0.6667 -0.2057 TD (r)Tj /F5 1 Tf 1.0714 0.0391 TD (by)Tj ET 0 0 0 RG 1 J 1 j 0.24 w 10 M []0 d 1 i 298.68 576 m 363.24 576 l S BT 10.08 0 0 10.08 328.44 580.08 Tm (1)Tj -5.1429 -0.5952 TD 0.477 Tc [(\(\))-7071(.)]TJ 2.2619 -1.0714 TD [(3)572([)-619(\(\))-1404(\(\))477(])]TJ /F7 1 Tf 6 0 0 6 313.32 560.465 Tm 4.38 Tc (as)Tj 10.08 0 0 10.08 269.16 573.556 Tm 0 Tc (D)Tj ET q 291.72 560.64 76.32 12.24 re W n BT /F12 1 Tf 10.08 0 2.143 10.08 307.08 562.8 Tm 2.305 Tc (mm)Tj ET Q BT /F12 1 Tf 10.08 0 0 10.08 290.52 573.36 Tm (=)Tj 5.381 -0.881 TD (\242)Tj -1.4762 -0.1667 TD (+)Tj /F3 1 Tf -4.9524 1.0562 TD (r)Tj 4.0714 -1.0476 TD 2.58 Tc (rr)Tj /F5 1 Tf 8.9286 1.1105 TD 0 Tc 0.012 Tw [( )24( )-6381(\(2\))]TJ -29.119 -3.0714 TD 0.008 Tc 0.313 Tw [(P)16(h)-16(o)32(t)0(o)32(n)8( d)8(e)23(n)-16(s)40(ity)56( v)32(alu)8(e)23(s)16( at )23(t)24(h)-16(e)23( d)8(e)23(te)23(c)23(t)0(o)32(r)-16(s)16( w)40(e)23(r)-16(e)23( c)23(o)32(mp)8(u)8(t)0(e)23(d)8( b)32(y)56( ap)8(p)8(l)0(y)56(i)0(n)-16(g)8( D)16(i)24(r)8(i)0(c)47(h)-16(le)23(t )-24(b)32(o)32(u)8(n)-16(d)32(a)23(r)-16(y)]TJ 0 -1.1429 TD 0.009 Tc 0.217 Tw [(c)24(o)33(n)-15(d)9(itio)57(n)-15(s)17( o)33(n)9( a)24(n)9( e)24(x)9(t)25(r)9(ap)9(o)33(l)1(a)24(t)1(e)24(d)9( b)33(o)33(u)9(n)-15(d)9(a)24(r)-15(y)57(.)-3( D)17(e)24(p)9(e)48(n)-15(d)9(i)25(n)9(g)9( o)33(n)9( t)25(h)-15(e)48( )-24(b)33(r)-15(e)24(a)1(s)17(t)25( )-24(s)17(i)25(ze)24(, t)25(h)-15(e)24( )-24(s)17(o)33(u)9(r)-15(c)24(e)24(s)17( )-24(a)24(n)-15(d)]TJ T* 0.008 Tc 0.147 Tw [(d)8(e)23(te)23(c)23(t)0(o)32(r)-16(s)16( )24(w)40(e)23(r)-16(e)23( )24(p)8(o)32(s)16(itio)32(n)-16(e)23(d)8( )24(1)8(\226)8(2)32( )24(t)24(r)8(a)23(n)-16(s)16(p)8(o)32(r)8(t )48(me)23(a)23(n)8( f)31(r)-16(e)23(e)23( p)8(a)23(t)24(h)-16(le)47(n)-16(g)32(t)24(h)-16(s)16( b)32(e)23(lo)8(w)40( t)24(h)-16(e)23( e)23(x)8(te)23(n)8(d)8(e)23(d)8( s)16(u)32(r)-16(f)31(ac)23(e)23(.)]TJ T* 0.242 Tw [(S)16(o)32(lu)8(tio)32(n)-16(s)16( )48(to)32( )24(t)24(h)-16(e)23( d)32(i)0(f)31(f)31(u)8(s)16(i)-24(o)32(n)-16( e)23(q)8(u)32(atio)56(n)-16( w)40(e)23(r)-16(e)23( c)23(o)32(mp)8(u)8(t)0(e)23(d)8( u)8(s)40(i)24(n)-16(g)32( t)24(h)-16(e)23( )]TJ 26.2856 0 TD -0.008 Tc 0.258 Tw [(KASKADE)8( a)-16(d)16(a)-16(p)16(t)-16(i)-16(v)16(e)7( f)15(i)-16(n)-32(i)8(t)-16(e)]TJ -26.2856 -1.1429 TD 0.008 Tc 0.147 Tw [(e)23(l)0(e)23(m)0(e)23(n)-16(t)24( )24(me)23(t)24(h)-16(o)32(d)8( )24([)31(1)8(1)8(])31(. )24( T)24(h)8(is)16( )24(is)16( )24(a p)8(u)8(b)32(lic)23(ly)56( av)32(ail)24(ab)32(le)23( c)23(o)32(d)8(e)23( s)16(u)8(itab)32(le)23( f)31(o)32(r)-16( t)24(h)-16(e)23( s)16(o)32(lu)8(tio)56(n)-16( o)32(f)31( p)8(a)23(r)-16(t)24(ia)23(l)]TJ T* 0.385 Tw [(d)8(i)0(f)31(f)8(e)23(r)-16(e)23(n)8(ti)24(al)24( e)23(q)8(u)8(a)0(t)24(i)0(o)32(n)-16(s)16( )24(i)24(n)8( o)32(n)-16(e)23(,)20( tw)40(o)32( o)32(r)-16( t)24(h)8(r)-16(e)23(e)23( d)32(ime)47(n)-16(s)16(io)32(n)-16(s)40(, )24(u)8(s)16(i)24(n)-16(g)32( ad)32(ap)8(t)24(i)0(v)32(e)23( )-24(f)31(i)0(n)-16(i)24(te)23( )-24(e)23(l)0(e)23(m)0(e)47(n)-16(t)]TJ 0 -1.119 TD -0.015 Tc 0.051 Tw [(t)-23(ech)-15(n)-39(i)-23(q)9(u)-15(es)-7(.)-27( )24( F)-7(o)9(r)-39( o)9(u)9(r)-39( )24(p)-15(u)9(r)-39(p)-15(o)9(s)-7(es)-7(,)-27( w)17(e)0( m)-23(o)9(d)-15(i)-23(f)8(i)-23(ed)-15( t)-23(h)-39(e b)9(a)-23(s)-7(i)-23(c co)9(d)-15(e)0( t)-23(o)9( en)-15(a)-23(b)9(l)-23(e)0( s)-7(o)9(l)-23(u)-15(t)-23(i)-23(o)9(n)-39(s)-7( )24(t)-23(o)9( th)-39(e )-24(d)9(i)-23(f)8(f)8(u)-15(s)-7(i)-23(o)9(n)]TJ 0 -1.1429 TD 0.008 Tc 0.123 Tw [(e)23(q)8(u)8(atio)56(n)-16( w)40(i)0(t)24(h)8( a)23( p)8(o)32(i)24(n)-16(t)24( s)16(o)32(u)8(r)-16(c)23(e)23(.)-4( )24( F)16(i)0(g)8(u)32(r)-16(e)47( 2)8( )24(il)24(lu)8(s)16(t)24(r)8(ate)23(s)16( t)24(h)-16(e)47( )-24(d)8(a)23(ta)23( )-24(ac)23(q)8(u)32(is)16(it)24(io)32(n)8( )-24(g)8(e)23(o)32(m)0(e)23(t)0(r)-16(y)56( )-24(e)23(m)0(p)8(l)0(o)8(y)32(e)23(d)8(.)]TJ T* 0.009 Tc 0.027 Tw [(T)25(h)-15(e)24( )24(a)24(r)9(r)-15(o)33(w)41(s)17( )24(i)25(n)-15( )48(t)25(h)-15(e)24( )24(f)32(i)1(g)9(u)33(r)-15(e)24( )24(s)41(h)-15(o)33(w)41( tw)17(o)33( d)9(i)1(f)32(f)9(e)24(r)-15(e)24(n)-15(t)25( lo)33(c)24(atio)57(n)-15(s)17( o)33(f)32( s)17(o)33(u)9(r)-15(c)24(e)24(s)17( u)9(s)17(e)24(d)9( f)9(o)33(r)-15( t)25(h)-15(e)48( )24(r)-15(e)24(p)9(o)33(r)-15(t)1(e)24(d)9( s)41(t)1(u)9(d)9(i)1(e)24(s)17(.)]TJ T* 0.008 Tc 0.123 Tw [(W)23(h)-16(ic)47(h)-16(e)23(v)32(e)23(r)-16( o)32(f)31( th)-16(e)23( )24(tw)40(o)32( s)-8(o)32(u)8(r)-16(c)23(e)23(s)16( is)16( a)23(d)8(o)32(p)8(te)23(d)8(,)-4( )24(t)24(h)-16(e)23( p)8(o)32(s)16(itio)56(n)-16( o)32(f)31( t)24(h)-16(e)23( d)8(e)23(te)23(c)23(t)0(o)32(r)-16( )-24(c)23(o)32(r)8(r)-16(e)23(s)16(p)8(o)32(n)-16(d)32(i)24(n)-16(g)32( )-24(to)32( )-24(t)24(h)-16(e)]TJ T* 0.005 Tc 0.031 Tw [(s)13(o)29(ur)-19(c)20(e)20( lo)29(c)20(atio)29(n)-19( )24(is)13( de)20(s)13(i)-3(g)29(n)5(ate)20(d )24(as)13( )24(0\260.)17( )24(T)21(h)-19(e)20( a)20(ngul)21(a)20(r)5( i)21(n)-19(c)44(r)-19(e)20(m)-3(e)44(n)-19(t)21( o)29(f)28( )-24(th)-19(e)20( )-24(de)20(te)20(c)20(t)-3(o)29(r)-19(s)13( )-24(w)37(a)-3(s)13( made)20( i)21(n)5( )-24(s)13(t)-3(e)20(p)5(s)]TJ T* -0.015 Tc 0.027 Tw [(o)-15(f)8( 1)-15(0)-15(\260)-20( p)9(r)-39(o)9(ceed)-15(i)-23(n)-39(g)9( in)-15( th)-39(e)24( cl)-23(o)9(c)0(k)-39(w)17(i)-23(s)-7(e d)-15(i)-23(r)-39(ect)-23(i)-23(o)9(n)-15(.)]TJ /F7 1 Tf 0 -17.052 TD 0 Tc 0.012 Tw [(2.)-12(3)24( D)8(e)-8(f)16(i)-8(ni)16(t)-8(i)-8(o)24(n o)24(f)-8( )24(Se)-8(ns)8(i)16(t)-8(i)16(v)-8(i)16(t)-8(y)15( and)24( E)16(dge)15( R)16(e)-8(s)8(o)0(l)-8(u)24(t)-8(i)-8(o)24(n)]TJ /F5 1 Tf 0 -1.6861 TD 0.008 Tc 0.194 Tw [(W)23(e)23( )23(d)8(e)23(f)31(i)0(n)-16(e)23( )23(me)23(as)16(u)32(r)-16(e)23(m)0(e)47(n)-16(t)24( )23(s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56( as)16( t)24(h)-16(e)47( )23(r)-16(e)23(la)23(tiv)32(e)23( c)23(h)8(a)23(n)-16(g)8(e)23( i)24(n)8( d)8(e)23(te)23(c)23(t)0(o)32(r)8( )23(r)-16(e)23(s)16(p)8(o)32(n)-16(s)16(e)23( b)32(e)23(t)-24(w)40(ee)23(n)-16( )23(a)]TJ 0 -1.1429 TD 0 Tc 0.083 Tw [(de)15(f)23(i)-8(n)-24(e)15(d b)24(a)-8(c)15(kgr)-24(o)24(u)24(n)-24(d)24( a)15(n)-24(d)24( t)16(a)15(r)-24(g)0(e)15(t)16( m)-8(e)15(di)16(um)16( \(b)24(a)-8(c)15(kg)24(r)-24(o)24(un)-24(d)24( +)16( e)15(m)-8(b)24(e)15(dde)15(d o)24(b)0(j)16(e)-8(c)15(t)-8(s)8(\))0(.)-12( T)16(h)-24(e)15( )-24(b)24(a)-8(c)15(k)0(g)24(r)-24(o)24(u)0(n)-24(d)]TJ T* -0.015 Tc 0.194 Tw [(m)-23(e)0(d)-15(i)-23(u)-15(m)1( )24(r)-39(e)0(f)8(e)0(r)-39(s)-7( t)-23(o)9( ca)-23(s)-7(e)0(s)-7( w)17(h)-39(er)-39(e)24( o)9(n)-39(l)-23(y)33( th)-39(e a)-23(d)9(i)-23(p)-15(o)9(s)-7(e an)-39(d)-15( )24(p)-15(a)0(r)-39(e)24(n)-39(c)24(h)-39(y)33(m)-23(a)-23( t)-23(i)-23(s)-7(s)-7(u)-15(es)-7( ar)-39(e)24( p)9(r)-39(es)-7(en)-39(t. Th)-39(e)]TJ T* 0 Tc 0.083 Tw [(t)-8(a)15(r)-24(g)0(e)15(t)16( m)-8(e)15(di)16(um)16( )23(r)-24(e)15(f)23(e)15(r)-24(s)8( t)-8(o)24( c)15(a)-8(s)8(e)15(s)8( )-24(w)32(h)-24(e)15(r)-24(e)15( a)-8( t)-8(u)24(m)-8(o)24(r)-24( ha)-8(s)8( )-24(b)24(e)15(e)15(n)-24( i)16(n)-24(t)16(r)-24(o)24(duc)15(e)15(d)0( )-24(i)16(n)0(t)-8(o)24( )-24(t)16(h)-24(e)15( )-24(b)24(a)-8(c)15(k)0(g)24(r)-24(o)24(und.)12( )-24( )-24(W)15(e)]TJ 0 -1.3571 TD [(us)8(e)15( )]TJ /F12 1 Tf 11.28 0 0 13.68 144.36 178.32 Tm 0.476 Tc (\(\))Tj /F7 1 Tf 5.04 0 0 5.04 156.84 174.938 Tm 0 Tc 0 Tw (t)Tj 10.08 0 0 10.08 137.88 178.996 Tm (u)Tj /F3 1 Tf 1.0238 0.0129 TD (r)Tj /F5 1 Tf 1.2143 0.0391 TD -0.015 Tc 0.336 Tw [( an)-39(d)9( )]TJ /F12 1 Tf 11.28 0 0 13.68 194.04 178.32 Tm 0.476 Tc (\(\))Tj /F7 1 Tf 5.04 0 0 5.04 206.52 174.938 Tm 0 Tc 0 Tw (b)Tj 10.08 0 0 10.08 187.56 178.996 Tm (u)Tj /F3 1 Tf 1.0238 0.0129 TD (r)Tj /F5 1 Tf 1.3095 0.0391 TD -0.015 Tc 0.336 Tw [(t)-23(o)9( r)-39(e)0(p)9(r)-39(es)-7(en)-15(t)-23( )23(th)-39(e co)9(m)-23(p)-15(u)-15(t)-23(ed)-15( d)-15(e)0(t)-23(ect)-23(o)9(r)-15( )23(r)-39(e)0(s)-7(p)-15(o)9(n)-39(s)-7(e)0( )-24(f)8(r)-39(o)9(m)-23( )-24(th)-15(e )-24(tar)-39(g)-15(et)-23( an)-39(d)]TJ -9.2857 -1.4762 TD 0.009 Tc 0.003 Tw [(b)33(a)1(c)24(k)9(g)9(r)-15(o)33(u)9(n)-15(d)33( )24(me)24(d)9(i)1(u)9(m)25(,)21( )24(r)-15(e)24(s)17(p)9(e)24(c)24(tiv)33(e)24(l)-23(y)57(.)-3( T)25(h)-15(e)24(n)9( s)17(e)48(n)-15(s)17(it)25(iv)33(ity)57( is)17( d)9(e)24(f)32(i)1(n)-15(e)24(d)9( as)41(:)]TJ /F12 1 Tf 11.28 0 0 13.68 260.04 150 Tm 0.476 Tc [(\(\))-1191(\()-21(\))]TJ 1.3617 -1.1579 TD (\(\))Tj ET 253.08 145.2 m 308.28 145.2 l S BT /F7 1 Tf 6 0 0 6 272.52 146.705 Tm 4.82 Tc (bt)Tj -5.76 -1.08 TD 0 Tc 0 Tw (u)Tj 8.32 -1.56 TD (b)Tj 10.08 0 0 10.08 253.56 150.676 Tm 2.667 Tc (uu)Tj 1.5238 -1.5714 TD 0 Tc (u)Tj /F12 1 Tf 10.08 0 2.143 10.08 232.2 142.56 Tm (d)Tj 10.08 0 0 10.08 278.52 150.72 Tm (-)Tj -3.3333 -0.8095 TD (=)Tj /F3 1 Tf 1.8571 0.8181 TD 2.723 Tc (rr)Tj 1.5476 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421.8 353.04 l f* BT /F12 1 Tf 6.96 0 0 6.96 404.76 374.4 Tm (q)Tj ET 408.84 372.72 m 409.56 372 l 411.48 371.04 l 412.92 371.04 l 413.64 371.28 l 415.32 371.76 l 416.76 372.24 l 417.72 372.72 l 411.48 372.24 m 408.84 372.72 l 410.04 370.56 l 416.04 370.8 m 417.72 372.72 l 415.32 372.96 l S BT /F5 1 Tf 6.96 0 0 6.96 399.72 375.155 Tm (2)Tj ET endstream endobj 25 0 obj << /ProcSet [/PDF /Text ] /Font << /F3 4 0 R /F5 5 0 R /F7 6 0 R /F9 7 0 R /F12 26 0 R >> /ExtGState << /GS1 8 0 R >> >> endobj 28 0 obj << /Length 23066 >> stream 1 1 1 rg /GS1 gs 21 -66 612 792 re f BT /F5 1 Tf 10.08 0 0 10.08 117.48 711.6 Tm 0 0 0 rg -0.015 Tc 0.027 Tw [(an)-39(d)-15( )24(i)-23(d)-15(e)24(n)-39(ti)-23(f)8(i)-23(es)-7( th)-39(e )24(r)-39(e)0(l)-23(a)0(t)-23(i)-23(v)9(e in)-39(f)8(l)-23(u)-15(e)0(n)-39(ce th)-39(e)24( a)-23(d)9(d)-15(e)0(d)-15( t)-23(u)9(m)-23(o)9(r)-15( )24(h)-15(a)-23(s)-7( o)9(n)-15( s)-7(u)9(r)-39(f)8(a)-23(ce d)-15(e)0(t)-23(ect)-23(o)9(r)-39( )24(r)-39(e)0(s)-7(p)-15(o)9(n)-39(s)-7(e)0(s)-7(.)]TJ 3.5714 -1.1429 TD 0.008 Tc 0.075 Tw [(M)16(e)23(as)16(u)8(r)-16(e)23(s)16( o)32(f)31( e)23(d)8(g)8(e)23( r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( w)40(e)23(r)-16(e)23( o)32(b)32(tain)-16(e)23(d)32( b)8(y)56( co)32(mp)8(u)8(t)0(i)24(n)-16(g)32( t)24(h)-16(e)23( e)23(d)8(g)8(e)23( )-24(s)16(p)32(r)-16(e)47(ad)8( )-24(f)31(u)32(n)-16(c)23(tio)32(n)8(,)]TJ -3.5714 -1.1429 TD -0.015 Tc [(co)9(r)-39(r)-39(ect)-23(ed)-15( f)8(o)9(r)-39( th)-39(e ex)-15(p)-15(ect)-23(ed)-15( in)-39(f)8(l)-23(u)-15(e)24(n)-39(ce o)9(f)8( t)-23(h)-39(e tu)-15(m)-23(o)33(r)-39( g)-15(e)0(o)9(m)-23(etr)-39(y)33(.)-27( )-23( )-23(Th)-15(i)-23(s)-7( i)-23(s)-7( )-23(d)-15(e)0(f)8(i)-23(n)-39(e)0(d)9( )-23(a)-23(s)-7( th)-39(e )-23(ex)-15(ces)-7(s)-7( )-23(o)-15(f)]TJ T* 0.008 Tc 0.29 Tw [(t)24(h)-16(e)23( )24(f)31(u)8(ll\226)8(w)40(i)0(d)8(t)24(h)8( )24(a)23(t)0( )48(h)8(alf)31(\226)8(m)24(ax)8(i)24(m)0(u)32(m)0( )24(\()8(F)16(W)23(H)40(M)16(\))8( )24(o)32(f)31( th)-16(e)23( s)16(e)47(n)-16(s)16(it)24(iv)32(ity)56( c)23(u)8(r)-16(v)32(e)23( ab)8(o)8(v)32(e)23( its)16( t)24(h)-16(e)23(o)32(r)-16(e)23(t)24(i)0(c)23(a)0(l)]TJ T* 0.171 Tw [(mi)24(n)8(imu)32(m)24( v)32(alu)8(e)23(,)20( )]TJ /F7 1 Tf 7.0952 -0.052 TD -0.016 Tc [(i.)-28(e)]TJ /F5 1 Tf 0.9524 0.052 TD 0.012 Tc [(.,)24( )]TJ /F7 1 Tf 0.9286 -0.052 TD -0.008 Tc 0.187 Tw [(E)-16(F)8(W)15(H)0(M)-8( = F)8(W)15(HM)-8( -)15( F)8(W)15(HM)]TJ 6.48 0 0 6.48 330.6 663.469 Tm 0.019 Tc [(ge)19(om)]TJ /F5 1 Tf 10.08 0 0 10.08 344.76 665.52 Tm 0.01 Tc 0.169 Tw [(, )24(i)26(n)10( w)42(h)-14(ic)49(h)-14( )]TJ /F7 1 Tf 4.7143 -0.052 TD -0.016 Tc [(FW)7(H)-8(M)]TJ 6.48 0 0 6.48 422.04 663.469 Tm 0.019 Tc [(ge)19(o)38(m)0( )]TJ 10.08 0 0 10.08 439.56 664.996 Tm -0.008 Tc (= )Tj /F5 1 Tf 1.119 0.052 TD 0 Tc [(2s)32(i)16(n)]TJ 6.48 0 0 6.48 467.4 669.806 Tm (-1)Tj 10.08 0 0 10.08 472.92 665.52 Tm 0 Tw (\()Tj /F7 1 Tf 0.3333 -0.052 TD (r)Tj /F5 1 Tf 0.381 0.052 TD (/)Tj /F7 1 Tf 0.2857 -0.052 TD (R)Tj /F5 1 Tf 0.619 0.052 TD -0.023 Tc (\),)Tj -36.881 -1.1191 TD -0.015 Tc [(w)17(h)-39(er)-39(e )]TJ /F7 1 Tf 2.8571 -0.052 TD 0 Tc (r)Tj /F5 1 Tf 0.381 0.052 TD -0.015 Tc 0.17 Tw [( an)-39(d)9( )]TJ /F7 1 Tf 2.2619 -0.052 TD 0 Tc 0 Tw (R)Tj /F5 1 Tf 0.5952 0.052 TD -0.015 Tc 0.194 Tw [( )24(r)-39(e)0(s)-7(p)-15(ect)-23(i)-23(v)9(el)-47(y)33( a)-23(r)-39(e th)-39(e)24( )24(r)-39(a)-23(d)9(i)-23(i o)9(f)8( t)-23(h)-39(e ce)24(n)-39(t)-23(e)24(r)-39(ed)-15( in)-39(clu)-15(s)-7(i)-23(o)9(n)-15( an)-15(d)-15( o)9(f)8( )-23(th)-39(e )-23(m)-23(e)0(d)-15(i)1(u)-15(m)1(,)-27( a)-23(s)]TJ -6.0952 -1.1428 TD 0.241 Tw [(s)-7(h)-39(o)9(w)17(n)-39( in)-15( F)-7(i)-23(g)9(u)9(r)-39(e 3)9(.)-27( )24( Th)-39(e)24(r)-39(ef)8(o)9(r)-39(e,)-27( a )-24(d)-15(ecr)-39(ea)-23(s)-7(e)0( )-24(in)-15( E)-23(F)-7(WH)17(M)-7( )-24(s)-7(i)-23(g)-15(n)-15(i)-23(f)8(i)-23(es)-7( )-24(an)-39( i)-23(m)1(p)9(r)-39(o)9(v)9(e)0(d)-15( )-24(r)-39(e)0(s)-7(o)9(l)-23(u)-15(t)-23(i)-23(o)9(n)]TJ T* 0.17 Tw [(o)-15(b)9(t)-23(a)-23(i)1(n)-39(e)0(d)-15(,)-3( w)17(h)-39(er)-39(ea)-23(s)17( an)-15( )24(in)-39(cr)-39(ea)-23(s)-7(e)0( in)-39( E)-23(F)-7(WH)17(M)-7( )-24(m)-23(ean)-39(s)-7( a)-23( l)-23(o)9(s)-7(s)-7( )-24(o)-15(f)8( )-24(r)-39(e)0(s)-7(o)9(l)-23(u)-15(t)-23(i)-23(o)9(n)-15(.)-27( )-24(We )-24(in)-15(tr)-39(o)9(d)-15(u)-15(ce )-24(th)-39(i)-23(s)]TJ T* 0 Tc 0.179 Tw [(c)15(o)24(r)-24(r)-24(e)15(c)15(t)-8(i)-8(o)24(n )24(f)23(a)-8(c)15(t)-8(o)24(r)-24( )24(i)16(n)-24( o)48(r)-24(de)15(r t)-8(o)24( d)24(i)-8(f)23(f)23(e)15(r)-24(e)15(n)-24(t)-8(i)16(a)-8(t)-8(e)15( v)24(a)15(ri)-8(a)-8(t)16(i)-8(o)24(n)-24(s)32( i)16(n)0( t)16(h)-24(e)15( e)15(dge)15(-s)8(p)24(r)-24(e)15(a)-8(d)24( f)23(u)0(n)-24(c)15(t)16(i)-8(o)24(n)0( c)15(a)-8(us)8(e)15(d)0( by)]TJ T* 0.107 Tw [(c)15(h)-24(a)15(nge)15(s)8( i)16(n)0( t)16(h)-24(e)15( d)24(i)-8(m)-8(e)39(n)-24(s)8(i)-8(o)48(n)-24( )24(a)15(n)-24(d)24( p)24(r)-24(o)24(p)0(e)15(r)-24(t)16(i)-8(e)15(s)8( o)24(f)23( t)-8(h)-24(e)15( b)24(a)-8(c)15(k)0(g)24(r)-24(o)24(und m)-8(e)15(d)24(i)-8(u)24(m)-8( f)47(r)-24(o)24(m)-8( c)39(h)-24(a)15(n)-24(ge)15(s)8( )24(i)16(n)-24( t)-8(u)24(m)-8(o)24(r)]TJ T* 0.008 Tc 0.099 Tw [(s)16(ize)23(. )47( )47( )24(I)31(n)-16( )47(t)24(h)-16(e)23( )24(ab)32(s)16(e)23(n)-16(c)23(e)23( o)8(f)31( th)8(is)16( c)23(o)32(r)8(r)-16(e)23(c)23(tio)32(n)8(,)-4( c)23(o)32(mp)8(a)23(r)8(is)16(o)32(n)-16(s)16( b)32(e)23(tw)40(e)23(e)23(n)-16( me)23(d)8(i)0(a)23( )24(h)-16(a)0(v)32(i)24(n)8(g)8( d)32(i)0(f)31(f)31(e)23(r)-16(e)23(n)-16(t)0( )24(tu)32(mo)32(r)]TJ T* 0.123 Tw [(s)16(ize)23(s)16( c)23(o)32(u)8(l)0(d)8( b)32(e)23( amb)32(ig)8(u)8(o)32(u)8(s)16(. )24( F)16(o)32(r)8( e)23(x)8(amp)32(le)23(,)20( c)23(e)23(r)-16(t)24(a)0(i)24(n)8(ly)56( it is)40( t)24(h)-16(e)23( c)23(a)0(s)16(e)23( )24(t)24(h)-16(a)23(t)0( )24(t)24(h)-16(e)23( w)40(i)0(d)8(t)24(h)8( o)32(f)31( )-24(th)-16(e)23( )-24(e)23(d)8(g)8(e)]TJ T* 0.147 Tw [(s)16(p)8(r)-16(e)23(ad)32( f)31(u)8(n)-16(c)23(t)24(i)0(o)32(n)8( w)40(ill )24(i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(e)23( w)40(ith)8( i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(i)24(n)8(g)8( )24(tu)32(mo)32(r)-16( s)40(ize)23( e)23(v)32(e)23(n)-16( )24(i)24(n)-16( )24(a)23( )24(n)-16(o)32(n)-16(-)8(s)16(c)23(at)24(te)23(r)8(i)24(n)-16(g)32( )-24(me)23(d)32(i)0(u)8(m)24(.)]TJ T* 0.009 Tc 0.003 Tw [(A)17(s)17( d)9(i)1(s)17(c)24(u)9(s)17(s)17(e)24(d)9( la)24(te)24(r)9(,)-3( w)41(h)9(ile)24( )24(t)25(h)-15(is)41( d)9(e)24(f)32(i)1(n)9(itio)57(n)-15( )24(is)17( v)33(a)1(l)25(i)1(d)9(,)21( i)25(t)1( )24(is)17( )-24(c)24(o)33(r)9(r)-15(e)24(c)24(t)1( in)9( )]TJ /F7 1 Tf 25.119 -0.052 TD 0.008 Tc [(a)32(b)8(s)16(o)8(lu)32(te)]TJ /F5 1 Tf 3.3571 0.052 TD 0.009 Tc 0.027 Tw [( )24(te)48(r)-15(m)1(s)41( o)33(n)9(ly)57( in)9( c)24(a)1(s)17(e)24(s)17( o)33(f)]TJ -28.4762 -1.1429 TD 0.008 Tc 0.313 Tw [(c)23(o)32(mp)8(ar)8(is)16(o)32(n)-16(s)16( )-24(b)32(e)23(tw)40(ee)23(n)-16( )-24(b)32(r)-16(e)23(a)0(s)16(t)24( map)8(s)40( h)-16(a)0(v)32(i)24(n)-16(g)32( )-24(t)24(h)-16(e)23( )-24(s)40(ame)23( d)8(i)24(ame)23(te)47(r)-16(.)-4( )-24(O)40(n)8( t)24(h)-16(e)23( )-24(o)32(t)24(h)-16(e)23(r)8( h)-16(a)23(n)8(d)8(,)20( )-24(i)24(n)]TJ T* 0.242 Tw [(c)23(o)32(mp)8(ar)8(is)16(o)32(n)-16(s)16( )48(mad)8(e)23( )48(i)24(n)-16(v)32(o)32(l)0(v)32(i)0(n)-16(g)8( )48(ma)23(p)8(s)16( )24(o)32(f)31( )24(d)8(i)0(f)31(f)8(e)23(r)-16(e)23(n)-16(t)24( d)32(i)0(a)23(m)0(e)23(t)0(e)23(r)-16(s)40(,)-4( )24(a v)32(a)23(r)8(iat)24(io)32(n)8( i)24(n)8( t)24(h)-16(e)47( EF)16(W)23(H)40(M)16( is)]TJ T* 0.009 Tc 0.003 Tw [(e)24(v)33(id)9(e)24(n)-15(c)24(e)24( o)9(f)32( a c)24(h)9(a)24(n)-15(g)9(e)24( )24(i)25(n)-15( )24(t)25(h)-15(e)24( e)24(d)9(g)9(e)24( )24(r)-15(e)24(s)17(o)33(lu)9(tio)33(n)9( )24(r)-15(e)24(l)25(ativ)33(e)24( to)33( t)25(h)-15(e)24( s)41(ize)24( o)33(f)32( t)25(h)-15(e)24( me)24(d)33(i)1(u)9(m)25(.)]TJ /F7 1 Tf 0 -1.7663 TD 0 Tc [(2.)-12(4)]TJ /F9 1 Tf 10.08 0 2.143 10.08 130.2 509.76 Tm 0 Tw ( )Tj /F7 1 Tf 10.08 0 0 10.08 135.48 509.716 Tm 0.004 Tc -0.016 Tw [(P)20(a)4(r)12(a)4(m)12(eter)12( Spac)19(e)]TJ /F5 1 Tf -1.7857 -1.6861 TD -0.015 Tc 0.265 Tw [(We )24(h)-39(a)-23(v)9(e)0( )24(ex)-15(am)-23(in)-39(ed)-15( )48(th)-39(e )24(d)-15(e)0(p)-15(e)24(n)-39(d)-15(en)-39(ce )24(o)9(f)8( )24(d)-15(e)0(t)-23(ect)-23(o)9(r)-39( s)-7(e)0(n)-39(s)-7(i)-23(t)1(i)-23(v)9(i)-23(t)-23(y)33( t)-23(o)9( t)-23(h)-39(e)24( in)-39(cl)-23(u)-15(d)-15(e)0(d)9( t)-23(u)9(m)-23(o)9(r)-15( an)-15(d)-15( )24(i)-23(t)-23(s)]TJ 0 -1.1429 TD 0.008 Tc 0.48 Tw [(d)8(e)23(r)-16(i)0(v)32(e)23(d)8( )24(e)23(d)8(g)8(e)23( )24(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( o)32(n)-16( f)31(o)32(u)8(r)8( o)32(f)31( s)16(e)0(v)32(e)23(n)-16( p)32(r)-16(i)24(n)-16(c)23(i)0(p)32(a)0(l)24( p)8(a)23(r)8(a)23(me)23(te)23(r)-16(s)40( as)16(s)16(o)32(c)23(iate)23(d)8( w)40(i)0(t)24(h)8( t)24(h)-16(e)]TJ T* -0.015 Tc 0.098 Tw [(m)-23(e)0(a)-23(s)-7(u)9(r)-39(em)-23(en)-15(t)-23( )47(an)-39(d)9( )23(tar)-39(g)-15(et d)-15(o)9(m)-23(a)0(in)-39(s)-7( d)9(i)1(r)-39(ect)-23(l)-23(y)33(,)-27( an)-39(d)-15(,)-3( b)9(eca)-23(u)-15(s)-7(e o)-15(f)8( k)-15(n)-39(o)9(w)17(n)-39( )23(r)-39(e)0(l)-23(a)0(t)-23(i)-23(o)33(n)-39(s)17(h)-39(i)-23(p)-15(s)17(,)-27( b)-15(y)33( in)-39(f)8(e)0(r)-39(e)0(n)-39(c)0(e)]TJ T* 0.008 Tc 0.075 Tw [(f)8(o)32(r)-16( )23(t)24(h)-16(e)47( )23(o)32(t)0(h)-16(e)47(r)8( )23(t)24(h)8(r)-16(e)23(e)23( )23(p)32(a)23(r)-16(a)23(me)23(te)23(r)-16(s)40(. )47( )23(T)24(h)-16(o)32(s)16(e)23( d)8(i)24(r)-16(e)23(c)23(tly)56( e)23(x)8(ami)24(n)-16(e)23(d)8( w)40(e)23(r)-16(e)23( v)32(a)0(r)8(i)0(a)23(tio)32(n)-16(s)40( i)24(n)8( b)32(r)-16(e)23(a)0(s)16(t)24( )23(a)23(n)-16(d)8( )23(tu)32(mo)32(r)]TJ T* 0.009 Tc 0.122 Tw [(s)17(ize)24(, )48(a)24(n)-15(d)33( )24(b)33(a)1(c)24(k)9(g)9(r)-15(o)33(u)33(n)-15(d)33( t)25(i)1(s)17(s)17(u)9(e)24( a)24(n)-15(d)33( tu)33(mo)33(r)9( c)24(o)33(n)-15(t)25(r)9(a)1(s)17(t)25(, )24(as)17( w)41(e)24(ll as)41( t)25(h)-15(e)48( i)25(n)-15(f)32(l)1(u)9(e)48(n)-15(c)24(e)24( o)9(f)32( v)33(iew)41( an)-15(g)33(l)1(e)24( )24(a)24(n)-15(d)]TJ T* 0.008 Tc 0.028 Tw [(s)16(o)32(u)8(r)-16(c)23(e)23( p)8(o)32(s)16(itio)32(n)-16(.)20( I)31(n)-16(f)31(e)23(r)8(r)-16(e)23(d)32( p)8(a)23(r)8(a)23(me)23(te)23(r)-16(s)40( i)24(n)-16(c)23(l)0(u)32(d)8(e)23( t)24(h)-16(e)23( im)24(p)8(a)0(c)23(t)24( )-24(o)32(f)31( )-24(s)16(t)0(r)-16(u)8(c)23(t)0(u)32(r)8(al)24( h)-16(e)23(te)23(r)-16(o)32(g)8(e)23(n)-16(e)23(i)24(t)0(y)56(,)-4( )-24(c)23(h)-16(o)32(i)0(c)23(e)23( )-24(o)8(f)]TJ T* 0.009 Tc 0.003 Tw [(illu)33(mi)25(n)9(a)24(ti)25(n)-15(g)33( w)41(a)1(v)33(e)24(le)24(n)-15(g)9(t)25(h)-15( )24(a)24(n)-15(d)33( u)9(s)17(e)24( o)33(f)32( c)24(o)33(n)-15(t)1(r)9(a)1(s)17(t)25( ag)9(e)48(n)-15(ts)41(. )-24(I)32(n)9( )-24(e)24(a)1(c)24(h)9( )-24(c)24(a)1(s)17(e)24(,)21( )-24(a)24( r)-15(a)24(n)9(g)9(e)24( )-24(o)33(f)32( )-24(p)9(a)1(r)9(ame)24(te)48(r)9( )-24(v)33(alu)9(e)24(s)]TJ T* 0.027 Tw [(w)41(a)1(s)17( )24(e)24(x)9(p)9(l)1(o)33(r)-15(e)24(d)9( )24(i)25(n)9( )24(a)24(n)9( )24(e)24(f)32(f)9(o)33(r)-15(t)1( )24(to)33( b)33(e)24(tte)24(r)-15( d)9(e)24(f)32(i)1(n)-15(e)48( t)25(h)-15(e)24(i)25(r)9( i)25(n)-15(f)32(l)1(u)9(e)48(n)-15(c)24(e)24( o)33(n)-15( )24(th)-15(e)48( c)24(o)33(mp)9(u)9(t)1(e)24(d)9( s)17(e)48(n)-15(s)17(it)25(iv)33(ity)57( an)-15(d)33( e)24(d)9(g)9(e)]TJ T* 0.008 Tc [(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8(.)]TJ 3.5714 -1.1429 TD 0.147 Tw [(Tab)32(le)23( 1)32( lis)40(ts)16( t)24(h)-16(e)47( d)8(i)24(ame)23(te)47(r)-16(s)16( o)32(f)31( t)24(h)-16(e)23( b)32(r)-16(e)23(a)0(s)16(t)24( )24(map)8(s)40( a)23(n)-16(d)32( t)24(u)8(mo)56(r)-16(s)16( e)23(x)8(p)8(l)0(o)32(r)-16(e)23(d)32(. T)24(h)-16(e)23(s)16(e)23( )-24(v)32(alu)8(e)23(s)]TJ -3.5714 -1.119 TD 0.075 Tw [(w)16(e)23(r)-16(e)23( s)16(e)23(le)23(c)23(t)0(e)23(d)8( o)32(n)-16( t)24(h)-16(e)47( b)32(a)0(s)16(i)0(s)16( o)32(f)31( th)-16(e)47( e)23(x)8(p)8(e)23(c)23(tatio)56(n)-16( )23(t)24(h)-16(a)23(t)0( )23(tu)8(mo)56(r)-16(s)16( c)23(a)23(n)8( b)32(e)23( lo)32(c)23(ate)23(d)8( al)24(mo)32(s)16(t)0( a)23(n)-16(y)56(w)40(h)-16(e)23(r)-16(e)23( )-24(i)24(n)]TJ 0 -1.1429 TD -0.015 Tc 0.146 Tw [(th)-39(e b)9(r)-39(ea)-23(s)-7(t)1( f)8(r)-39(o)9(m)-23( )24(n)-39(e)24(ar)-39( )24(th)-39(e )24(n)-15(i)-23(p)-15(p)-15(l)-23(e )24(t)-23(o)9( th)-39(e c)24(h)-39(es)-7(t)-23( w)17(a)-23(ll)-23(, )-24(an)-15(d)-15( th)-39(at)-23( )-24(b)33(r)-39(ea)-23(s)-7(t)-23( an)-39(d)9( )-24(t)-23(u)9(m)-23(o)9(r)-15( )-24(s)-7(i)1(z)-23(e)0( )-24(o)9(b)-15(v)9(i)-23(o)9(u)-15(s)-7(l)-47(y)]TJ T* 0.289 Tw [(v)9(a)-23(r)-39(y)33(.)-27( F)-7(o)9(r)-39( ea)-23(c)24(h)-15( o)9(f)8( t)-23(h)-39(e s)-7(e)0(v)9(e)0(n)-39( b)9(r)-39(ea)-23(s)17(t)-23( d)9(i)-23(am)-23(et)-23(er)-39(s)17( ex)-15(am)-23(in)-39(ed)-15(, )-24(w)17(e)0( )-24(a)-23(d)-15(d)-15(i)1(t)-23(i)-23(o)9(n)-15(a)-23(ll)-23(y)33( )-24(ex)-15(p)-15(l)-23(o)9(r)-39(ed)-15( )-24(f)8(i)-23(v)9(e)]TJ T* 0.027 Tw [(d)-15(i)-23(f)8(f)-15(er)-39(en)-15(t)-23( c)24(r)-39(o)9(s)-7(s)-7(\226)-15(s)-7(ect)-23(i)-23(o)9(n)-39(a)-23(l)-23( )24(ar)-39(ea)-23(s)-7( o)9(ccu)-15(p)-15(i)-23(ed)-15( b)-15(y)33( t)-23(h)-39(e )24(t)-23(u)-15(m)-23(o)33(r)-39(.)]TJ 3.5714 -19.7619 TD 0.075 Tw [(T)-23(a)-23(b)9(l)-23(e)0( )24(2)9( )24(d)-15(e)0(f)8(i)-23(n)-39(e)0(s)-7( th)-39(e o)9(p)-15(ti)-23(ca)-23(l co)9(e)-23(f)-15(f)8(i)-23(ci)-23(en)-39(t)-23(s)-7( a)-23(s)-7(s)-7(i)1(g)9(n)-39(ed)-15( )24(t)-23(o)9( an)-15( em)-23(b)9(e)0(d)-15(d)-15(e)0(d)-15( t)-23(u)-15(m)-23(o)9(r)-15(.)-3( )24(Th)-39(e v)9(a)-23(l)-23(u)-15(es)]TJ -3.5714 -1.1429 TD 0 Tc 0.012 Tw [(s)8(e)15(l)-8(e)15(c)15(t)-8(e)15(d)0( )-24(w)32(e)15(r)-24(e)15( b)24(a)-8(s)8(e)15(d pri)-8(m)16(a)15(r)-24(i)16(l)-8(y)48( o)24(n)-24( r)-24(e)15(po)24(rt)-8(s)8( )24(i)16(n)-24( )24(t)16(h)-24(e)15( l)16(i)-8(t)-8(e)39(r)-24(a)15(t)-8(u)24(r)-24(e)15( )24(r)-24(e)15(g)24(a)-8(rdi)16(ng o)24(b)24(s)8(e)15(r)-24(v)24(e)15(d o)24(p)0(t)-8(i)-8(c)15(a)-8(l)-8( )-24(p)24(r)-24(o)24(p)0(e)15(r)-24(t)16(i)-8(e)15(s)]TJ T* [(of)23( e)15(x)0(c)15(i)-8(s)8(e)15(d n)-24(o)24(rm)-8(a)15(l)-8( )24(a)15(n)-24(d)24( c)15(a)15(n)-24(c)15(e)15(r)-24(o)24(u)0(s)8( b)24(r)-24(e)15(a)-8(s)8(t)16( t)16(i)-8(s)8(s)8(u)0(e)15( [12])23(.)-12( I)23(n)0( s)8(o)24(m)-8(e)15( c)15(a)-8(s)8(e)15(s)8(,)-12( a)15( m)-8(o)24(r)-24(e)15( )-24(e)15(x)0(t)-8(e)39(n)-24(d)0(e)15(d)0( ra)15(n)-24(g)0(e)15( )-24(w)32(a)-8(s)]TJ ET 1 1 1 rg 1 i 137.16 335.28 345.6 -176.88 re f* BT /F3 1 Tf 7.92 0 0 7.92 220.44 324.154 Tm 0 0 0 rg 0.013 Tc -0.021 Tw [(T)13(a)28(b)-7(l)18(e 1:)13( D)8(i)-12(am)28(et)13(ers)8( of)13( b)24(rea)28(s)8(t)13(s)-22( an)24(d)-7( emb)24(e)2(d)-7(d)24(ed)24( t)-18(u)-7(m)28(o)-2(rs)]TJ /F5 1 Tf 11.0909 -2.3613 TD -0.021 Tc 0.013 Tw [(T)-46(u)-36(mor)-21( D)-26(i)-16(a)-62(m)-31(et)-46(er)-52(s )-31( \()-52(c)-1(m)-31(\))]TJ -10 -1.7576 TD -0.001 Tc 0.024 Tw [(Co)14(rr)-32(e)-12(s)-6(p)14(o)-16(n)-16(d)14(in)-16(g)14( to)-16( )31(Ra)-12(ti)-26(o)14( o)-16(f)29( Cro)-16(ss)24(\226)-16(S)-21(e)-12(c)19(t)-26(i)4(o)-16(n)14(a)-12(l)4( A)24(r)-32(e)19(a)-12( o)-16(f)29( )31(T)-26(u)-16(m)-11(o)14(r to)-16( )31(Br)-32(e)19(a)-42(s)24(t)4( S)10(i)-26(z)-12(e)]TJ ET 147.48 313.2 0.72 -0.72 re f* 147.48 313.2 0.72 -0.72 re f* 148.2 313.2 28.08 -0.72 re f* 176.28 313.2 0.72 -0.72 re f* 177 313.2 42.48 -0.72 re f* 219.48 313.2 0.72 -0.72 re f* 220.2 313.2 251.28 -0.72 re f* 471.48 313.2 0.72 -0.72 re f* 471.48 313.2 0.72 -0.72 re f* 147.48 312.48 0.72 -29.76 re f* 176.28 312.48 0.72 -29.76 re f* 219.48 312.48 0.72 -29.76 re f* 471.48 312.48 0.72 -29.76 re f* BT 7.92 0 0 7.92 154.68 291.532 Tm 0.003 Tc [(Ca)-8(se)]TJ 0.7273 -1.7273 TD 0 Tc 0 Tw (#)Tj 3.5152 3.4848 TD [(Bre)20(a)-41(s)25(t)]TJ -0.5758 -1.7576 TD -0.02 Tc [(D)-25(i)-15(a)-31(m)-30(et)-45(er)]TJ 0.9091 -1.7273 TD 0 Tc [(\(c)-11(m)20(\))]TJ 4.7879 -0.3636 TD 0.015 Tc -0.023 Tw [( 0.)23(0625 %)-2970(0)0(.)23(25%)-4243( 1%)-4122( 2.)23(25%)-4122( 4%)]TJ ET 147.48 282.72 0.72 -0.72 re f* 176.28 282.72 0.72 -0.72 re f* 219.48 282.72 0.72 -0.72 re f* 220.2 282.72 49.68 -0.72 re f* 269.88 282.72 0.72 -0.72 re f* 270.6 282.72 49.68 -0.72 re f* 320.28 282.72 0.72 -0.72 re f* 321 282.72 49.68 -0.72 re f* 370.68 282.72 0.72 -0.72 re f* 371.4 282.72 49.68 -0.72 re f* 421.08 282.72 0.72 -0.72 re f* 421.8 282.72 49.68 -0.72 re f* 471.48 282.72 0.72 -0.72 re f* 147.48 282 0.72 -14.4 re f* 176.28 282 0.72 -14.4 re f* 219.48 282 0.72 -14.4 re f* 269.88 282 0.72 -14.4 re f* 320.28 282 0.72 -14.4 re f* 370.68 282 0.72 -14.4 re f* 421.08 282 0.72 -14.4 re f* 471.48 282 0.72 -14.4 re f* BT 7.92 0 0 7.92 161.16 259.852 Tm -0.008 Tc [(I)-3857(1)-23(6)-4781(0)-23(.4)-5114(0)-23(.)0(8)-5114(1)-23(.6)-5114(2)-23(.)0(4)-5114(3)-23(.2)]TJ ET 147.48 267.6 0.72 -0.72 re f* 148.2 267.6 28.08 -0.72 re f* 176.28 267.6 0.72 -0.72 re f* 177 267.6 42.48 -0.72 re f* 219.48 267.6 0.72 -0.72 re f* 220.2 267.6 49.68 -0.72 re f* 269.88 267.6 0.72 -0.72 re f* 270.6 267.6 49.68 -0.72 re f* 320.28 267.6 0.72 -0.72 re f* 321 267.6 49.68 -0.72 re f* 370.68 267.6 0.72 -0.72 re f* 371.4 267.6 49.68 -0.72 re f* 421.08 267.6 0.72 -0.72 re f* 421.8 267.6 49.68 -0.72 re f* 471.48 267.6 0.72 -0.72 re f* 147.48 266.88 0.72 -13.92 re f* 176.28 266.88 0.72 -13.92 re f* 219.48 266.88 0.72 -13.92 re f* 269.88 266.88 0.72 -13.92 re f* 320.28 266.88 0.72 -13.92 re f* 370.68 266.88 0.72 -13.92 re f* 421.08 266.88 0.72 -13.92 re f* 471.48 266.88 0.72 -13.92 re f* BT 7.92 0 0 7.92 159.72 245.212 Tm 0.015 Tc [(I)15(I)-3682(12)-4758(0.)23(3)-5091(0)0(.)23(6)-5091(1.)23(2)-5091(1)0(.)23(8)-5091(2.)23(4)]TJ ET 147.48 252.96 0.72 -0.72 re f* 148.2 252.96 28.08 -0.72 re f* 176.28 252.96 0.72 -0.72 re f* 177 252.96 42.48 -0.72 re f* 219.48 252.96 0.72 -0.72 re f* 220.2 252.96 49.68 -0.72 re f* 269.88 252.96 0.72 -0.72 re f* 270.6 252.96 49.68 -0.72 re f* 320.28 252.96 0.72 -0.72 re f* 321 252.96 49.68 -0.72 re f* 370.68 252.96 0.72 -0.72 re f* 371.4 252.96 49.68 -0.72 re f* 421.08 252.96 0.72 -0.72 re f* 421.8 252.96 49.68 -0.72 re f* 471.48 252.96 0.72 -0.72 re f* 147.48 252.24 0.72 -13.92 re f* 176.28 252.24 0.72 -13.92 re f* 219.48 252.24 0.72 -13.92 re f* 269.88 252.24 0.72 -13.92 re f* 320.28 252.24 0.72 -13.92 re f* 370.68 252.24 0.72 -13.92 re f* 421.08 252.24 0.72 -13.92 re f* 471.48 252.24 0.72 -13.92 re f* BT 7.92 0 0 7.92 158.52 230.572 Tm [(I)15(I)15(I)-3501(10)-4515(0.)23(25)-4818(0.)23(5)-5091(1)0(.)23(0)-5091(1.)23(5)-5091(2)0(.)23(0)]TJ ET 147.48 238.32 0.72 -0.72 re f* 148.2 238.32 28.08 -0.72 re f* 176.28 238.32 0.72 -0.72 re f* 177 238.32 42.48 -0.72 re f* 219.48 238.32 0.72 -0.72 re f* 220.2 238.32 49.68 -0.72 re f* 269.88 238.32 0.72 -0.72 re f* 270.6 238.32 49.68 -0.72 re f* 320.28 238.32 0.72 -0.72 re f* 321 238.32 49.68 -0.72 re f* 370.68 238.32 0.72 -0.72 re f* 371.4 238.32 49.68 -0.72 re f* 421.08 238.32 0.72 -0.72 re f* 421.8 238.32 49.68 -0.72 re f* 471.48 238.32 0.72 -0.72 re f* 147.48 237.6 0.72 -13.92 re f* 176.28 237.6 0.72 -13.92 re f* 219.48 237.6 0.72 -13.92 re f* 269.88 237.6 0.72 -13.92 re f* 320.28 237.6 0.72 -13.92 re f* 370.68 237.6 0.72 -13.92 re f* 421.08 237.6 0.72 -13.92 re f* 471.48 237.6 0.72 -13.92 re f* BT 7.92 0 0 7.92 158.28 215.932 Tm -0.008 Tc [(I)-8(V)-3771(8)-5023(0)-23(.2)-5114(0)-23(.)0(4)-5114(0)-23(.8)-5114(1)-23(.)0(2)-5114(1)-23(.6)]TJ ET 147.48 223.68 0.72 -0.72 re f* 148.2 223.68 28.08 -0.72 re f* 176.28 223.68 0.72 -0.72 re f* 177 223.68 42.48 -0.72 re f* 219.48 223.68 0.72 -0.72 re f* 220.2 223.68 49.68 -0.72 re f* 269.88 223.68 0.72 -0.72 re f* 270.6 223.68 49.68 -0.72 re f* 320.28 223.68 0.72 -0.72 re f* 321 223.68 49.68 -0.72 re f* 370.68 223.68 0.72 -0.72 re f* 371.4 223.68 49.68 -0.72 re f* 421.08 223.68 0.72 -0.72 re f* 421.8 223.68 49.68 -0.72 re f* 471.48 223.68 0.72 -0.72 re f* 147.48 222.96 0.72 -13.92 re f* 176.28 222.96 0.72 -13.92 re f* 219.48 222.96 0.72 -13.92 re f* 269.88 222.96 0.72 -13.92 re f* 320.28 222.96 0.72 -13.92 re f* 370.68 222.96 0.72 -13.92 re f* 421.08 222.96 0.72 -13.92 re f* 471.48 222.96 0.72 -13.92 re f* BT 7.92 0 0 7.92 159.72 201.292 Tm 0.015 Tc [(V)-3899(6)-4758(0.)23(15)-4818(0.)23(3)-5091(0)0(.)23(6)-5091(0.)23(9)-5091(1)0(.)23(2)]TJ ET 147.48 209.04 0.72 -0.72 re f* 148.2 209.04 28.08 -0.72 re f* 176.28 209.04 0.72 -0.72 re f* 177 209.04 42.48 -0.72 re f* 219.48 209.04 0.72 -0.72 re f* 220.2 209.04 49.68 -0.72 re f* 269.88 209.04 0.72 -0.72 re f* 270.6 209.04 49.68 -0.72 re f* 320.28 209.04 0.72 -0.72 re f* 321 209.04 49.68 -0.72 re f* 370.68 209.04 0.72 -0.72 re f* 371.4 209.04 49.68 -0.72 re f* 421.08 209.04 0.72 -0.72 re f* 421.8 209.04 49.68 -0.72 re f* 471.48 209.04 0.72 -0.72 re f* 147.48 208.32 0.72 -13.92 re f* 176.28 208.32 0.72 -13.92 re f* 219.48 208.32 0.72 -13.92 re f* 269.88 208.32 0.72 -13.92 re f* 320.28 208.32 0.72 -13.92 re f* 370.68 208.32 0.72 -13.92 re f* 421.08 208.32 0.72 -13.92 re f* 471.48 208.32 0.72 -13.92 re f* BT 7.92 0 0 7.92 158.28 186.652 Tm -0.008 Tc [(V)17(I)-3796(4)-5023(0)-23(.1)-5114(0)-23(.)0(2)-5114(0)-23(.4)-5114(0)-23(.)0(6)-5114(0)-23(.8)]TJ ET 147.48 194.4 0.72 -0.72 re f* 148.2 194.4 28.08 -0.72 re f* 176.28 194.4 0.72 -0.72 re f* 177 194.4 42.48 -0.72 re f* 219.48 194.4 0.72 -0.72 re f* 220.2 194.4 49.68 -0.72 re f* 269.88 194.4 0.72 -0.72 re f* 270.6 194.4 49.68 -0.72 re f* 320.28 194.4 0.72 -0.72 re f* 321 194.4 49.68 -0.72 re f* 370.68 194.4 0.72 -0.72 re f* 371.4 194.4 49.68 -0.72 re f* 421.08 194.4 0.72 -0.72 re f* 421.8 194.4 49.68 -0.72 re f* 471.48 194.4 0.72 -0.72 re f* 147.48 193.68 0.72 -13.92 re f* 176.28 193.68 0.72 -13.92 re f* 219.48 193.68 0.72 -13.92 re f* 269.88 193.68 0.72 -13.92 re f* 320.28 193.68 0.72 -13.92 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-0.014 Tc (i.e)Tj /F5 1 Tf 0.9524 0.052 TD 0 Tc [(.)12(,)-12( )24(b)48(r)-24(e)15(a)-8(s)8(t)-8(\))23( f)23(o)24(r)-24( a)15( f)23(i)-8(xe)15(d i)16(n)-24(c)15(l)-8(us)32(i)-8(o)24(n)-24( )24(\(t)-8(u)24(m)-8(o)24(r)-24(\))23( c)15(o)24(n)-24(t)16(ra)-8(s)8(t)16( v)24(a)-8(l)-8(u)0(e)15( a)15(nd f)23(i)-8(xe)15(d )24(ra)-8(t)16(i)-8(o)24( o)24(f)]TJ -6.4762 -1.1429 TD -0.015 Tc 0.098 Tw [(in)-39(cl)-23(u)-15(s)-7(i)-23(o)9(n)-15( )23(ar)-39(ea )47(t)-23(o)9( )23(t)-23(a)0(r)-39(g)-15(et )47(ar)-39(ea)-23( )47(i)-23(s)-7( s)17(h)-39(o)9(w)17(n)-39( in)-15( F)-7(i)-23(g)9(u)9(r)-39(e 4)9(.)-27( )23(Th)-39(e tar)-39(g)-15(et d)-15(i)1(a)-23(m)-23(e)0(t)-23(e)24(r)-15( w)17(a)-23(s)-7( v)9(a)-23(r)-15(i)-23(ed)-15( b)9(e)0(t)-23(w)-7(een)-39( 2)]TJ T* 0.008 Tc 0.123 Tw [(a)23(n)-16(d)8( )48(1)8(6)8( )24(c)23(m)24( to)32( c)23(o)32(v)32(e)23(r)-16( t)24(h)-16(e)23( e)23(x)8(p)8(e)23(c)23(t)0(e)23(d)8( )24(r)-16(a)23(n)8(g)8(e)23( o)32(f)31( d)8(iame)23(te)47(r)-16(s)16( )24(i)24(n)-16( )24(t)24(h)-16(e)23( v)32(i)0(c)23(i)24(n)-16(i)24(ty)56( )-24(o)32(f)31( th)-16(e)23( )24(n)-16(i)24(p)8(p)8(l)0(e)23( )24(a)23(n)-16(d)32( c)23(h)-16(e)23(s)16(t)]TJ T* 0.052 Tw [(w)40(all. )24( C)8(o)56(n)-16(t)24(r)8(a)23(r)-16(y)56( to)32( w)40(h)-16(at o)56(n)-16(e)23( m)24(i)0(g)32(h)8(t e)23(x)8(p)8(e)23(c)23(t)0(,)20( w)40(e)23( o)8(b)32(s)-8(e)23(r)-16(v)32(e)23( in)8( a)23(l)0(l)24( c)23(a)0(s)16(e)23(s)16( )-23(s)16(t)0(u)8(d)8(i)0(e)23(d)32( )-23(t)24(h)8(at)24( )-23(a)23(n)8( )]TJ /F7 1 Tf 33 -0.052 TD -0.016 Tc [(in)-16(c)-24(r)-8(ea)-16(s)-8(e)]TJ /F5 1 Tf 3.3571 0.052 TD 0.076 Tw [( in)]TJ ET 1 1 1 rg 1 i 159.24 502.8 302.4 -115.2 re f* BT /F3 1 Tf 7.92 0 0 7.92 237.72 491.674 Tm 0 0 0 rg 0.012 Tc -0.02 Tw [(T)12(a)27(b)-8(l)17(e 2:)12( Op)23(t)-19(i)17(ca)27(l)-13( p)23(r)1(op)23(ert)12(i)17(e)1(s)7( of)12( )-31(t)12(u)-8(m)27(o)-3(r t)12(i)17(s)7(s)7(u)23(e)]TJ /F5 1 Tf -6.3636 -2.9371 TD 0.003 Tc [(Gro)18(u)-12(p)]TJ 7.9394 1.1818 TD [(Ca)-8(se)]TJ 0.7273 -1.1818 TD 0 Tc 0 Tw (#)Tj /F12 1 Tf 7.92 0 1.683 7.92 329.64 476.88 Tm (m)Tj /F7 1 Tf 5.04 0 0 5.04 334.2 475.658 Tm (a)Tj /F5 1 Tf 7.92 0 0 7.92 322.2 467.932 Tm -0.008 Tw [(\( c)-11(m)]TJ 5.04 0 0 5.04 336.36 471.36 Tm [(-1)-24( )]TJ 7.92 0 0 7.92 341.88 467.932 Tm 0 Tw (\))Tj /F12 1 Tf 7.92 0 1.683 7.92 404.28 476.88 Tm (m)Tj /F7 1 Tf 5.04 0 0 5.04 408.84 475.658 Tm (s)Tj /F5 1 Tf 7.92 0 0 7.92 410.76 477.052 Tm (\264)Tj -1.6667 -1.1515 TD -0.008 Tw [(\( c)-11(m)]TJ 5.04 0 0 5.04 411.72 471.36 Tm [(-1)-24( )]TJ 7.92 0 0 7.92 417.24 467.932 Tm 0 Tw (\))Tj ET 173.88 485.52 0.72 -0.72 re f* 173.88 485.52 0.72 -0.72 re f* 174.6 485.52 45.12 -0.72 re f* 219.72 485.52 0.72 -0.72 re f* 220.44 485.52 74.88 -0.72 re f* 295.32 485.52 0.72 -0.72 re f* 296.04 485.52 74.64 -0.72 re f* 370.68 485.52 0.72 -0.72 re f* 371.4 485.52 74.64 -0.72 re f* 446.04 485.52 0.72 -0.72 re f* 446.04 485.52 0.72 -0.72 re f* 173.88 484.8 0.72 -22.32 re f* 219.72 484.8 0.72 -22.32 re f* 295.32 484.8 0.72 -22.32 re f* 370.68 484.8 0.72 -22.32 re f* 446.04 484.8 0.72 -22.32 re f* BT 7.92 0 0 7.92 191.88 454.492 Tm 0.015 Tc -0.023 Tw [(\()15(A)40(\))-5713(5)0(,)23( 6,)23( 7)-7364(0)0(.)23(0)0(8)-6576(40,)23( 20,)23( 10)]TJ ET 173.88 462.48 0.72 -0.72 re f* 174.6 462.48 45.12 -0.72 re f* 219.72 462.48 0.72 -0.72 re f* 220.44 462.48 74.88 -0.72 re f* 295.32 462.48 0.72 -0.72 re f* 296.04 462.48 74.64 -0.72 re f* 370.68 462.48 0.72 -0.72 re f* 371.4 462.48 74.64 -0.72 re f* 446.04 462.48 0.72 -0.72 re f* 173.88 461.76 0.72 -13.68 re f* 219.72 461.76 0.72 -13.68 re f* 295.32 461.76 0.72 -13.68 re f* 370.68 461.76 0.72 -13.68 re f* 446.04 461.76 0.72 -13.68 re f* BT 7.92 0 0 7.92 192.12 440.092 Tm [(\()15(B)15(\))-5713(1,)23( 2,)23( 3)-7606(0)0(.)23(2)-6849(40,)23( 20,)23( 10)]TJ ET 173.88 448.08 0.72 -0.72 re f* 174.6 448.08 45.12 -0.72 re f* 219.72 448.08 0.72 -0.72 re f* 220.44 448.08 74.88 -0.72 re f* 295.32 448.08 0.72 -0.72 re f* 296.04 448.08 74.64 -0.72 re f* 370.68 448.08 0.72 -0.72 re f* 371.4 448.08 74.64 -0.72 re f* 446.04 448.08 0.72 -0.72 re f* 173.88 447.36 0.72 -13.68 re f* 219.72 447.36 0.72 -13.68 re f* 295.32 447.36 0.72 -13.68 re f* 370.68 447.36 0.72 -13.68 re f* 446.04 447.36 0.72 -13.68 re f* BT 7.92 0 0 7.92 192.12 425.692 Tm [(\()15(C)15(\))-5713(7,)23( 3,)23( 9)-5606(0)0(.)23(08,)23( 0.)23(2,)23( 0.)23(4)-6334(1)0(0)]TJ ET 173.88 433.68 0.72 -0.72 re f* 174.6 433.68 45.12 -0.72 re f* 219.72 433.68 0.72 -0.72 re f* 220.44 433.68 74.88 -0.72 re f* 295.32 433.68 0.72 -0.72 re f* 296.04 433.68 74.64 -0.72 re f* 370.68 433.68 0.72 -0.72 re f* 371.4 433.68 74.64 -0.72 re f* 446.04 433.68 0.72 -0.72 re f* 173.88 432.96 0.72 -13.68 re f* 219.72 432.96 0.72 -13.68 re f* 295.32 432.96 0.72 -13.68 re f* 370.68 432.96 0.72 -13.68 re f* 446.04 432.96 0.72 -13.68 re f* BT 7.92 0 0 7.92 191.88 411.292 Tm -0.008 Tc 0 Tw [(\()-8(D)-13(\))-6190(4)-23(, 8)-7023(0)-23(.2)-23(, 0)-23(.)0(0)-23(8)-7508(5)]TJ ET 173.88 419.28 0.72 -0.72 re f* 174.6 419.28 45.12 -0.72 re f* 219.72 419.28 0.72 -0.72 re f* 220.44 419.28 74.88 -0.72 re f* 295.32 419.28 0.72 -0.72 re f* 296.04 419.28 74.64 -0.72 re f* 370.68 419.28 0.72 -0.72 re f* 371.4 419.28 74.64 -0.72 re f* 446.04 419.28 0.72 -0.72 re f* 173.88 418.56 0.72 -13.68 re f* 173.88 404.88 0.72 -0.72 re f* 173.88 404.88 0.72 -0.72 re f* 174.6 404.88 45.12 -0.72 re f* 219.72 418.56 0.72 -13.68 re f* 219.72 404.88 0.72 -0.72 re f* 220.44 404.88 74.88 -0.72 re f* 295.32 418.56 0.72 -13.68 re f* 295.32 404.88 0.72 -0.72 re f* 296.04 404.88 74.64 -0.72 re f* 370.68 418.56 0.72 -13.68 re f* 370.68 404.88 0.72 -0.72 re f* 371.4 404.88 74.64 -0.72 re f* 446.04 418.56 0.72 -13.68 re f* 446.04 404.88 0.72 -0.72 re f* 446.04 404.88 0.72 -0.72 re f* 1 1 1 rg 116.04 394.8 374.4 -136.8 re f* BT /F3 1 Tf 7.92 0 0 7.92 220.44 383.674 Tm 0 0 0 rg 0.015 Tc -0.023 Tw [(T)15(a)30(bl)20(e 3:)15( Op)26(t)-16(i)20(ca)30(l)-10( p)26(r)4(op)26(ert)15(i)20(e)4(s)10( of)15( )-31(ba)30(c)-26(k)56(grou)26(nd)26( t)15(i)20(s)10(s)-20(u)26(e)]TJ 7.303 -2.4242 TD 0.013 Tc [(A)8(d)24(i)18(p)24(os)8(e)-11755(P)18(a)28(ren)24(ch)-7(yma)]TJ ET 127.08 372.96 0.72 -0.72 re f* 127.08 372.96 0.72 -0.72 re f* 127.8 372.96 62.4 -0.72 re f* 190.2 372.96 0.72 -0.72 re f* 190.92 372.96 35.28 -0.72 re f* 226.2 372.96 0.72 -0.72 re f* 226.92 372.96 129.84 -0.72 re f* 356.76 372.96 0.72 -0.72 re f* 357.48 372.96 125.28 -0.72 re f* 482.76 372.96 0.72 -0.72 re f* 482.76 372.96 0.72 -0.72 re f* 127.08 372.24 0.72 -20.4 re f* 190.2 372.24 0.72 -20.4 re f* 226.2 372.24 0.72 -20.4 re f* 356.76 372.24 0.72 -20.4 re f* 482.76 372.24 0.72 -20.4 re f* BT /F5 1 Tf 7.92 0 0 7.92 149.16 346.492 Tm 0.003 Tc [(Gro)18(u)-12(p)]TJ 6.5455 0.0303 TD [(Ca)-8(se)]TJ 0.697 -1.1818 TD 0 Tc 0 Tw (#)Tj /F12 1 Tf 7.92 0 1.683 7.92 256.68 343.2 Tm (m)Tj /F7 1 Tf 5.04 0 0 5.04 261.24 341.978 Tm (a)Tj /F5 1 Tf 7.92 0 0 7.92 250.68 334.252 Tm [(\(c)-11(m)]TJ 5.04 0 0 5.04 262.92 337.68 Tm (-1)Tj 7.92 0 0 7.92 267.24 334.252 Tm (\))Tj /F12 1 Tf 7.92 0 1.683 7.92 321.24 343.2 Tm (m)Tj /F7 1 Tf 5.04 0 0 5.04 325.8 341.978 Tm (s)Tj /F5 1 Tf 7.92 0 0 7.92 327.72 343.372 Tm (\264)Tj -1.4848 -1.1515 TD [(\(c)-11(m)]TJ 5.04 0 0 5.04 328.2 337.68 Tm (-1)Tj 7.92 0 0 7.92 332.52 334.252 Tm (\))Tj /F12 1 Tf 7.92 0 1.683 7.92 385.08 343.2 Tm (m)Tj /F7 1 Tf 5.04 0 0 5.04 389.64 341.978 Tm (a)Tj /F5 1 Tf 7.92 0 0 7.92 379.08 334.252 Tm [(\(c)-11(m)]TJ 5.04 0 0 5.04 391.32 337.68 Tm (-1)Tj 7.92 0 0 7.92 395.64 334.252 Tm (\))Tj /F12 1 Tf 7.92 0 1.683 7.92 447.24 343.2 Tm (m)Tj /F7 1 Tf 5.04 0 0 5.04 451.8 341.978 Tm (s)Tj /F5 1 Tf 7.92 0 0 7.92 453.72 343.372 Tm (\264)Tj -1.4849 -1.1515 TD [(\(c)-11(m)]TJ 5.04 0 0 5.04 454.2 337.68 Tm (-1)Tj 7.92 0 0 7.92 458.52 334.252 Tm (\))Tj ET 127.08 351.84 0.72 -0.72 re f* 190.2 351.84 0.72 -0.72 re f* 226.2 351.84 0.72 -0.72 re f* 226.92 351.84 66.96 -0.72 re f* 293.88 351.84 0.72 -0.72 re f* 294.6 351.84 62.16 -0.72 re f* 356.76 351.84 0.72 -0.72 re f* 357.48 351.84 62.4 -0.72 re f* 419.88 351.84 0.72 -0.72 re f* 420.6 351.84 62.16 -0.72 re f* 482.76 351.84 0.72 -0.72 re f* 127.08 351.12 0.72 -24.24 re f* 190.2 351.12 0.72 -24.24 re f* 226.2 351.12 0.72 -24.24 re f* 293.88 351.12 0.72 -24.24 re f* 356.76 351.12 0.72 -24.24 re f* 419.88 351.12 0.72 -24.24 re f* 482.76 351.12 0.72 -24.24 re f* BT 7.92 0 0 7.92 136.2 318.892 Tm 0.015 Tc [(H)10(o)0(m)35(oge)35(neo)30(u)-30(s)-3021(1)-5394(0.)23(04)-6818(10)-6576(0.)23(04)-6515(10)]TJ ET 127.08 326.88 0.72 -0.72 re f* 127.8 326.88 62.4 -0.72 re f* 190.2 326.88 0.72 -0.72 re f* 190.92 326.88 35.28 -0.72 re f* 226.2 326.88 0.72 -0.72 re f* 226.92 326.88 66.96 -0.72 re f* 293.88 326.88 0.72 -0.72 re f* 294.6 326.88 62.16 -0.72 re f* 356.76 326.88 0.72 -0.72 re f* 357.48 326.88 62.4 -0.72 re f* 419.88 326.88 0.72 -0.72 re f* 420.6 326.88 62.16 -0.72 re f* 482.76 326.88 0.72 -0.72 re f* 127.08 326.16 0.72 -14.4 re f* 190.2 326.16 0.72 -14.4 re f* 226.2 326.16 0.72 -14.4 re f* 293.88 326.16 0.72 -14.4 re f* 356.76 326.16 0.72 -14.4 re f* 419.88 326.16 0.72 -14.4 re f* 482.76 326.16 0.72 -14.4 re f* BT 7.92 0 0 7.92 153.72 303.772 Tm -0.023 Tw [(\()15(A)40(\))-4288(2)0(,)23( 3,)23( 4)-2122(0)0(.)23(02,)23( 0.)23(04,)23( 0.)23(08)-4546(10)-6576(0.)23(08)-6788(7)]TJ ET 127.08 311.76 0.72 -0.72 re f* 127.8 311.76 62.4 -0.72 re f* 190.2 311.76 0.72 -0.72 re f* 190.92 311.76 35.28 -0.72 re f* 226.2 311.76 0.72 -0.72 re f* 226.92 311.76 66.96 -0.72 re f* 293.88 311.76 0.72 -0.72 re f* 294.6 311.76 62.16 -0.72 re f* 356.76 311.76 0.72 -0.72 re f* 357.48 311.76 62.4 -0.72 re f* 419.88 311.76 0.72 -0.72 re f* 420.6 311.76 62.16 -0.72 re f* 482.76 311.76 0.72 -0.72 re f* 127.08 311.04 0.72 -14.4 re f* 190.2 311.04 0.72 -14.4 re f* 226.2 311.04 0.72 -14.4 re f* 293.88 311.04 0.72 -14.4 re f* 356.76 311.04 0.72 -14.4 re f* 419.88 311.04 0.72 -14.4 re f* 482.76 311.04 0.72 -14.4 re f* BT 7.92 0 0 7.92 153.96 288.652 Tm [(\()15(B)15(\))-4288(3,)23( 7,)23( 8)-4394(0)0(.)23(0)0(4)-5303(10,)23( 15,)23( 25)-5061(0.)23(08)-6788(7)]TJ ET 127.08 296.64 0.72 -0.72 re f* 127.8 296.64 62.4 -0.72 re f* 190.2 296.64 0.72 -0.72 re f* 190.92 296.64 35.28 -0.72 re f* 226.2 296.64 0.72 -0.72 re f* 226.92 296.64 66.96 -0.72 re f* 293.88 296.64 0.72 -0.72 re f* 294.6 296.64 62.16 -0.72 re f* 356.76 296.64 0.72 -0.72 re f* 357.48 296.64 62.4 -0.72 re f* 419.88 296.64 0.72 -0.72 re f* 420.6 296.64 62.16 -0.72 re f* 482.76 296.64 0.72 -0.72 re f* 127.08 295.92 0.72 -14.4 re f* 190.2 295.92 0.72 -14.4 re f* 226.2 295.92 0.72 -14.4 re f* 293.88 295.92 0.72 -14.4 re f* 356.76 295.92 0.72 -14.4 re f* 419.88 295.92 0.72 -14.4 re f* 482.76 295.92 0.72 -14.4 re f* BT 7.92 0 0 7.92 153.96 273.532 Tm [(\()15(C)15(\))-4804(5,)23( 6)-4879(0)0(.)23(0)0(4)-6818(1)0(0)-6576(0)0(.)23(0)0(8)-5758(15,)23( 25)]TJ ET 127.08 281.52 0.72 -0.72 re f* 127.8 281.52 62.4 -0.72 re f* 190.2 281.52 0.72 -0.72 re f* 190.92 281.52 35.28 -0.72 re f* 226.2 281.52 0.72 -0.72 re f* 226.92 281.52 66.96 -0.72 re f* 293.88 281.52 0.72 -0.72 re f* 294.6 281.52 62.16 -0.72 re f* 356.76 281.52 0.72 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F)41(i)1(g)9(u)33(r)-15(e)24( 5)33(\()9(a\))9(\))32(,)-3( )24(a)24(n)-15(d)33( i)25(m)1(p)33(r)-15(o)33(v)33(e)24(s)17( e)24(d)9(g)9(e)24( )-24(r)-15(e)24(s)17(o)33(lu)9(tio)33(n)-15( )-24(s)41(lig)33(h)9(tly)57( )-24(\()]TJ /F7 1 Tf 21.3333 -0.052 TD 0.008 Tc (cf)Tj /F5 1 Tf 0.7381 0.052 TD 0 Tc 0.036 Tw [(.)12( F)8(i)16(gu)24(r)-24(e)15( 6\()23(a)-8(\))0(\))23(.)]TJ -31.8809 -1.1429 TD 0.083 Tw [(R)24(e)15(s)8(u)0(l)-8(t)-8(s)8( i)-8(n)0( F)8(i)16(gu)24(r)-24(e)15(s)8( 5\(b)24(\) a)15(nd 6)24(\()0(b)24(\))0( de)15(m)-8(o)24(n)-24(s)8(t)16(r)0(a)-8(t)-8(e)15( )23(t)16(h)-24(e)15( c)15(o)24(rr)-24(e)15(s)8(po)24(n)-24(d)0(i)-8(n)0(g)24( )23(r)-24(e)15(s)8(p)0(o)24(n)-24(s)8(e)15( )23(t)-8(o)24( v)24(a)-8(ri)-8(a)15(t)-8(i)-8(o)24(n)-24(s)32( i)16(n)0( t)16(h)-24(e)]TJ T* 0.008 Tc 0.218 Tw [(b)32(r)-16(e)23(a)0(s)16(t)0( d)32(i)0(a)23(m)0(e)23(t)0(e)23(r)8( f)31(o)32(r)-16( f)31(i)0(x)8(e)23(d)8( v)32(alu)8(e)23(s)16( o)32(f)31( t)24(h)-16(e)23( a)23(r)-16(e)23(a)23( r)8(atio)32(.)20( )-24( )-24(A)16(g)32(ai)24(n)8(,)20( )-24(a)23( )-24(p)8(o)32(s)16(itiv)32(e)23( )-24(c)23(o)32(r)-16(r)-16(e)23(l)24(a)0(t)24(i)0(o)32(n)8( )-24(is)16( )-24(s)16(e)23(e)23(n)]TJ T* 0.385 Tw [(b)32(e)23(t)-24(w)40(ee)23(n)-16( )24(s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56( )24(a)23(n)-16(d)32( )24(ta)23(r)8(g)8(e)23(t )24(s)16(i)24(ze)23( w)40(h)-16(e)47(n)-16( e)23(i)24(t)24(h)-16(e)47(r)-16( o)56(n)-16(e)23( o)32(f)31( th)-16(e)23( s)16(i)24(ze)23( p)32(a)23(r)-16(a)23(me)23(te)47(r)-16(s)16( is)40( f)31(i)0(x)8(e)23(d)8(.)]TJ T* -0.015 Tc 0.217 Tw [(I)-15(n)-15(t)-23(er)-39(es)-7(tin)-39(g)-15(l)-23(y)33(,)-27( )23(th)-39(e )47(m)-23(a)0(x)-15(i)1(m)-23(u)-15(m )23(r)-15(a)-23(t)-23(e)0( o)9(f)8( s)-7(e)0(n)-39(s)-7(i)-23(t)1(i)-23(v)9(i)-23(t)-23(y)33( ch)-39(an)-39(g)-15(e)0( o)9(ccu)-15(r)-39(s)-7( w)17(h)-39(e)24(n)-39( ex)-15(tr)-39(em)-23(e)24( v)9(a)-23(l)-23(u)-15(es)-7( o)9(f)8( t)-23(h)-39(e)]TJ 0 -1.1191 TD 0.313 Tw [(t)-23(a)0(r)-39(g)-15(et g)-15(e)0(o)9(m)-23(et)-23(r)-39(y)33( ar)-39(e p)-15(a)0(ir)-39(ed)-15( \()]TJ /F7 1 Tf 12.1667 -0.052 TD 0.008 Tc [(i.)20(e.)]TJ /F5 1 Tf 1.2143 0.052 TD -0.015 Tc [(, b)9(r)-39(ea)-23(s)-7(t)1( an)-15(d)-15( )24(t)-23(u)-15(m)-23(o)33(r)-39( s)-7(i)1(z)-23(e)0(\))-15(.)-3( )24(Th)-39(u)-15(s)-7(, )24(th)-39(e )-23(g)9(r)-39(eat)-23(es)-7(t)-23( )-23(c)24(h)-39(an)-39(g)-15(e)24( )-23(in)]TJ -13.381 -1.1428 TD 0.008 Tc 0.123 Tw [(s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56( v)32(alu)8(e)23(s)16( )24(o)32(c)23(c)23(u)8(r)-16(s)16( w)40(ith)8( l)24(a)23(r)-16(g)8(e)23( b)32(r)-16(e)23(a)0(s)40(t)0(s)16( c)23(o)32(n)-16(t)24(ai)24(n)8(i)24(n)-16(g)32( s)16(m)24(al)24(l )24(tu)8(mo)56(r)-16(s)16( \()31(a)0( c)23(l)24(i)24(n)-16(ic)23(a)23(lly)56( in)8(te)23(r)-16(e)23(s)16(t)24(i)24(n)-16(g)]TJ T* -0.015 Tc 0.098 Tw [(ca)-23(s)-7(e)0(\))-15( \()-15(F)-7(i)-23(g)-15(u)9(r)-39(e 5)-15(\()8(a)-23(\))-15(\))8(,)-27( )23(an)-39(d)9( s)-7(m)1(a)-23(l)-23(l)1( b)9(r)-39(ea)-23(s)-7(t)-23(s)17( co)9(n)-39(t)1(a)-23(i)1(n)-15(i)1(n)-39(g)9( lar)-39(g)-15(e tu)-15(m)-23(o)9(r)-39(s)-7( )23(\()-15(F)-7(i)-23(g)9(u)9(r)-39(e )-24(5)-15(\()-15(b)9(\))-15(\))-15(.)-3( )-24( Th)-39(es)-7(e )-24(f)8(i)-23(n)-39(d)9(in)-39(g)-15(s)]TJ T* 0.009 Tc 0.003 Tw [(i)25(n)-15(d)9(i)1(c)24(a)24(t)1(e)24( t)25(h)9(at)25( s)17(e)24(n)-15(s)41(itiv)33(ity)57( r)-15(e)24(s)17(p)9(o)33(n)-15(s)17(e)24(s)17( d)9(o)33( )24(n)-15(o)33(t s)17(i)25(mp)9(ly)57( s)17(c)24(ale)24( w)41(ith)9( t)25(a)1(r)9(g)9(e)24(t)25( s)17(i)25(ze)24(.)]TJ 0 -20.619 TD 0 Tc [(3.)-12(1)24(.)-12(3 )]TJ /F7 1 Tf 2.4048 -0.052 TD 0.155 Tw [(I)23(n)0(f)-8(l)16(ue)-8(n)24(c)-8(e)15( of)16( Com)32(pos)8(i)-8(t)16(i)-8(o)0(n)24( of)16( T)8(a)0(r)8(g)0(e)15(t)-8( G)32(e)-8(om)8(e)15(t)-8(r)8(y)15( and)24( T)8(u)0(m)8(o)0(r)8( C)24(ont)-8(r)8(a)0(s)8(t)16( )-24(on)24( )-24(S)24(e)-8(ns)8(i)-8(t)16(i)-8(v)15(i)-8(t)16(y)-8( )]TJ /F5 1 Tf 33.9048 0.052 TD -0.024 Tc [(vs)-16(.)]TJ /F7 1 Tf -36.3095 -1.1949 TD 0 Tc -0.012 Tw [(E)-8(dge)15( R)-8(e)-8(s)8(ol)16(ut)-8(i)16(o)0(n)]TJ /F5 1 Tf 0 -1.6861 TD 0.202 Tw [(T)16(h)-24(e)15( )47(r)-24(e)15(s)8(u)0(l)-8(t)-8(s)32( )23(s)32(h)-24(o)24(w)32(n)-24( )23(i)16(n)0( F)8(i)-8(gu)24(r)-24(e)15(s)8( 7)24(\()0(a)-8(\)\226\(c)15(\))23( pl)-8(o)24(t)-8( )23(t)16(h)-24(e)15( )23(E)-8(F)8(W)15(H)32(M)8( ve)15(r)-24(s)8(us)8( s)8(e)15(n)-24(s)8(i)16(t)-8(i)-8(v)24(i)-8(t)-8(y)48( r)-24(e)15(s)8(p)0(o)24(n)-24(s)8(e)15( f)23(o)24(r)-24( a)]TJ 0 -1.2381 TD 0.008 Tc 0.123 Tw [(d)8(e)23(te)23(c)23(t)0(o)32(r)-16( p)8(o)32(s)16(itio)32(n)-16(e)23(d)8( )24(1)8(8)8(0)]TJ /F12 1 Tf 9.5714 -0.0477 TD 0 Tc 0 Tw (\260)Tj /F5 1 Tf 0.381 0.0477 TD 0.008 Tc 0.147 Tw [( )24(f)31(r)-16(o)32(m)0( )48(t)24(h)-16(e)23( )24(s)16(o)32(u)8(r)-16(c)23(e)23(,)20( as)16( f)31(u)32(n)-16(c)23(tio)56(n)-16(s)16( o)32(f)31( b)32(r)-16(e)23(a)0(s)16(t)0( s)16(i)24(ze)23(, )24(tu)32(mo)32(r)-16(\226)8(to)32(\226)8(b)32(r)-16(e)23(as)16(t)24( a)23(r)-16(e)47(a)]TJ -9.9524 -1.119 TD 0.009 Tc 0.027 Tw [(r)9(atio)33( )24(a)24(n)-15(d)33( tu)33(mo)33(r)9( c)24(o)33(n)-15(t)25(r)9(a)1(s)17(t)1(,)21( f)32(o)33(r)-15( t)25(h)-15(e)48( d)9(i)1(f)32(f)32(e)24(r)-15(e)24(n)-15(t)25( t)25(u)9(mo)33(r)9( c)24(o)33(n)-15(t)25(r)9(a)1(s)17(t)25( g)33(r)-15(o)33(u)9(p)9(s)17(. )24( I)32(n)9( )-24(F)17(i)1(g)33(u)33(r)-15(e)24(s)17( )-24(7)9(\()9(a)1(\))32( a)24(n)-15(d)9( 7)9(\()9(b)33(\))9( )-24(t)25(h)-15(e)]TJ 0 -1.1429 TD 0.008 Tc 0.099 Tw [(ab)32(s)16(o)32(r)-16(p)8(tio)32(n)8( )24(c)23(o)32(ef)8(f)31(i)0(c)23(i)0(e)23(n)-16(t )24(f)31(o)32(r)-16( )47(t)24(h)-16(e)23( tu)32(mo)32(r)8( is)40( f)31(i)0(x)8(e)23(d)8( a)23(t)0( 0)32(.)-4(0)8(8)32( c)23(m)]TJ 6.48 0 0 6.48 345 351.806 Tm -0.037 Tc (-1)Tj 0.8148 -0.9259 TD 0 Tc 0 Tw ( )Tj 10.08 0 0 10.08 352.92 347.52 Tm -0.024 Tc 0.131 Tw [(a)-9(n)-24(d)-24( 0.)-36(2 c)-9(m)]TJ 6.48 0 0 6.48 399 351.806 Tm 0 Tc (-1)Tj 10.08 0 0 10.08 404.52 347.52 Tm -0.015 Tc 0.122 Tw [(, )24(r)-39(e)0(s)-7(p)-15(ect)-23(i)-23(v)9(el)-47(y)33(,)-27( an)-39(d)9( th)-39(e)]TJ -28.4762 -1.1429 TD 0.008 Tc 0.099 Tw [(s)16(c)23(atte)23(r)8(i)24(n)-16(g)32( c)23(o)32(ef)8(f)31(i)0(c)23(i)0(e)23(n)-16(t v)32(a)23(r)-16(i)0(e)23(s)16( f)55(r)-16(o)32(m)0( 1)8(0)32( to)32( 4)8(0)32( c)23(m)]TJ 6.48 0 0 6.48 306.84 340.286 Tm 0 Tc (-1)Tj 10.08 0 0 10.08 312.12 336 Tm -0.015 Tc 0.122 Tw [(. I)8(n)-15( F)-7(i)-23(g)9(u)9(r)-39(e 7)-15(\()-15(c)0(\))-15( )24(th)-39(e s)-7(c)0(a)-23(t)1(t)-23(e)0(r)-15(i)1(n)-39(g)9( co)9(e)-23(f)-15(f)8(i)-23(ci)-23(en)-39(t)-23( o)9(f)]TJ -19.3095 -1.1429 TD 0.008 Tc 0.147 Tw [(t)24(h)-16(e)23( tu)32(mo)32(r)8( is)40( f)31(i)0(x)8(e)23(d)8( at)24( )-24(1)8(0)]TJ 6.48 0 0 6.48 218.04 328.766 Tm 0 Tc 0 Tw ( )Tj 10.08 0 0 10.08 221.4 324.48 Tm -0.015 Tc (cm)Tj 6.48 0 0 6.48 233.64 328.766 Tm 0 Tc (-1)Tj 10.08 0 0 10.08 238.92 324.48 Tm -0.015 Tc 0.194 Tw [( an)-15(d)-15( )24(th)-39(e a)-23(b)9(s)-7(o)9(r)-39(p)-15(ti)-23(o)9(n)-15( co)9(e)-23(f)-15(f)8(i)-23(ci)-23(en)-39(t)-23( v)9(a)0(r)-39(i)-23(ed)9( f)8(r)-39(o)9(m)-23( 0)9(.)-27(0)-15(8)9( t)-23(o)9( 0)9(.)-27(4)9( cm)]TJ 6.48 0 0 6.48 486.84 328.766 Tm 0 Tc (-1)Tj 10.08 0 0 10.08 492.36 324.48 Tm 0 Tw (.)Tj -37.1905 -1.1429 TD -0.015 Tc 0.051 Tw [(S)-7(h)-39(o)9(w)17(n)-39( ar)-39(e)24( th)-39(e )24(r)-39(e)0(s)-7(p)-15(o)9(n)-39(s)-7(e)0(s)-7( f)8(o)9(r)-39( th)-15(r)-39(ee d)9(i)-23(f)8(f)8(e)0(r)-39(e)0(n)-39(t)-23( )24(ar)-39(ea )24(r)-39(a)0(t)-23(i)-23(o)9(s)-7( \()-15(l)1(a)-23(b)9(el)-23(ed)-15( A)-7(,)-27( B)9(,)-3( C)-15(,)-3( w)17(h)-39(e)24(r)-39(e A)-7( co)9(r)-15(r)-39(es)-7(p)-15(o)9(n)-39(d)-15(s)]TJ T* 0 Tc 0.107 Tw [(t)-8(o)24( )24(0.)-12(062)24(5% )47(\()23(r)-24(e)15(d\),)12( )24(B)24( )24(t)-8(o)24( )24(1.)12(0%)23( )24(\(g)24(r)-24(e)15(e)15(n)-24(\))23(,)-12( )24(a)15(n)-24(d)24( C)24( t)-8(o)24( 4%)23( \(b)24(l)-8(u)0(e)15(\)\),)12( a)-8(s)32( a)15( f)23(u)0(n)-24(c)15(t)16(i)-8(o)24(n)-24( o)24(f)23( b)24(r)-24(e)15(a)-8(s)8(t)-8( )24(di)16(a)-8(m)-8(e)15(t)-8(e)39(r)-24(.)]TJ T* 0.008 Tc 0.075 Tw [(F)16(o)32(r)-16( )23(e)23(a)0(c)23(h)8( )23(l)24(i)24(n)-16(e)23( )23(d)32(r)8(aw)40(n)8(,)-4( )47(t)24(h)-16(e)23( s)16(e)23(n)-16(s)40(itiv)32(ity)56( i)24(n)-16(c)23(r)-16(e)23(a)0(s)16(e)23(s)16( )23(mo)32(n)-16(o)32(to)32(n)-16(i)0(c)23(a)23(lly)56( w)40(ith)8( i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(i)24(n)-16(g)32( b)32(r)-16(e)23(a)0(s)16(t)24( d)32(i)0(a)23(m)0(e)23(t)0(e)23(r)8(,)]TJ 0 -1.119 TD [(w)40(h)-16(ile)23( )23(at)24( t)24(h)-16(e)23( s)40(ame)23( )23(ti)24(me)23( t)24(h)-16(e)23( )23(EF)16(W)23(H)40(M)16( v)32(alu)8(e)23( mo)32(n)-16(o)32(to)32(n)8(i)0(c)23(a)0(l)24(l)0(y)56( )-24(d)8(e)0(c)23(r)-16(e)23(a)0(s)16(e)23(s)16(.)-4( )-24( I)31(n)-16(s)16(p)8(e)23(c)23(tio)32(n)-16( )-24(o)32(f)31( )-24(t)24(h)-16(is)40( )-24(s)16(i)0(x)8(\226)]TJ 0 -1.1429 TD 0.099 Tw [(d)8(ime)47(n)-16(s)16(io)32(n)8(a)0(l)24( d)32(a)0(t)24(a)0( s)16(e)23(t )24(r)-16(e)23(v)32(e)23(als)16( t)24(h)-16(e)47( f)31(o)32(llo)8(w)40(i)0(n)-16(g)8(.)20( )24( M)16(o)32(s)16(t)0( s)16(t)24(r)-16(i)0(k)32(i)24(n)-16(g)32( is)40( )-24(th)8(e)23( )-24(s)16(t)24(r)-16(o)56(n)-16(g)32( )-24(d)8(e)23(p)8(e)23(n)-16(d)8(e)47(n)-16(c)23(e)23( )-24(o)32(f)31( )-24(e)23(d)8(g)8(e)]TJ T* [(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( a)23(n)8(d)8( s)16(e)47(n)-16(s)16(i)24(tiv)32(ity)56( to)32( th)-16(e)47( tu)32(mo)32(r)8( o)32(n)8( )-24(b)32(r)-16(e)23(a)0(s)16(t)24( )-24(s)16(ize)47(, )-24(e)23(s)16(p)8(e)23(c)23(ially)56( )-24(f)8(o)32(r)-16( t)24(h)-16(e)23( )-24(s)16(m)24(al)24(le)23(r)8( )-24(tu)32(mo)32(r)-16(s)40(. )-24(I)31(n)]TJ T* -0.015 Tc 0.146 Tw [(th)-39(i)-23(s)-7( ca)-23(s)-7(e)0(, an)-15( )24(in)-39(cr)-39(ea)-23(s)-7(e)0( )24(in)-39( b)33(r)-39(ea)-23(s)-7(t)1( s)-7(i)-23(z)-23(e)0( )24(p)9(r)-39(ef)8(er)-39(en)-39(t)-23(i)1(a)-23(l)1(l)-23(y)33( en)-39(h)-15(a)0(n)-39(ces)-7( ed)-15(g)-15(e)0( )24(r)-39(e)0(s)-7(o)9(l)-23(u)-15(t)-23(i)-23(o)9(n)-39(,)-3( )-24(in)-15(d)-15(e)0(p)-15(e)0(n)-39(d)-15(e)24(n)-39(t )-24(o)9(f)]TJ T* 0 Tc 0.06 Tw [(t)-8(u)0(m)-8(o)24(r c)15(o)24(n)-24(t)16(ra)-8(s)8(t)16(.)-12( )24( I)23(n)-24(c)39(r)-24(e)15(a)-8(s)8(i)16(n)-24(g)24( t)16(u)0(m)-8(o)48(r)-24( s)8(i)16(z)-8(e)15( \(g)24(r)-24(o)24(ups)8( A)8(\226)24(C\) w)32(h)-24(e)39(n)0( t)16(h)-24(e)15( b)48(r)-24(e)15(a)-8(s)8(t)-8( s)32(i)-8(z)-8(e)15( )24(a)15(n)-24(d)24( t)-8(u)24(m)-8(o)24(r )-23(c)15(o)24(n)-24(t)16(ra)-8(s)8(t)]TJ T* 0.417 Tw [(v)24(a)-8(l)-8(u)0(e)15(s)8( a)15(r)-24(e)15( f)23(i)-8(xe)15(d p)24(r)0(i)-8(m)16(a)15(r)-24(i)16(l)-8(y)48( e)15(n)-24(ha)15(n)-24(c)15(e)15(s)8( s)8(e)15(n)-24(s)8(i)-8(t)16(i)-8(v)24(i)-8(t)-8(y)48(,)-12( a)-8(l)16(t)16(h)-24(o)24(ugh s)8(o)24(m)-8(e)15( e)15(nha)15(n)-24(c)15(e)15(m)-8(e)39(n)-24(t)16( i)16(n)0( )-23(e)15(dge)]TJ T* 0.107 Tw [(r)-24(e)15(s)8(o)24(l)-8(u)0(t)-8(i)-8(o)24(n i)-8(s)32( o)24(b)24(s)-16(e)15(r)-24(v)24(e)15(d fo)24(r)-24( l)16(a)15(r)-24(g)0(e)39(r)-24( )24(t)-8(u)24(m)-8(o)24(r)-24(s)8(.)12( )24(Co)24(m)-8(p)0(a)15(r)0(i)16(n)-24(g)24( )24(r)-24(e)15(s)8(u)0(l)-8(t)-8(s)8( )24(i)-8(n)0( )-24(P)32(a)15(n)-24(e)15(l)-8(s)8( \(a)-8(\)\226\(c)15(\))23( )-24(i)16(l)-8(l)-8(u)0(s)8(t)16(ra)-8(t)-8(e)15(s)8( t)16(h)-24(e)]TJ T* 0.009 Tc 0.003 Tw [(e)24(f)9(f)9(e)24(c)24(t)1( o)9(f)32( v)33(a)1(r)-15(y)57(in)-15(g)9( t)25(u)9(mo)33(r)9( c)24(o)33(n)-15(t)25(r)9(a)1(s)17(t)25(. )24( R)33(e)24(s)17(u)9(lts)17( i)25(n)9( P)17(a)24(n)-15(e)24(l)25( \()32(a)1(\))9( s)41(h)-15(o)33(w)41( )-24(th)9(a)24(t)1( at)25( )-24(mo)33(d)9(e)24(r)9(ate)24( ab)33(s)17(o)33(r)-15(p)9(tio)33(n)9( )-24(v)33(alu)9(e)24(s)]TJ T* 0 Tc 0 Tw (\()Tj /F7 1 Tf 0.3333 -0.052 TD 0.008 Tc [(i.)20(e.)]TJ /F5 1 Tf 1.2143 0.052 TD 0 Tc 0.083 Tw [(,)-12( )23(0.)-12(08)24( c)15(m)]TJ 6.48 0 0 6.48 171.96 190.766 Tm -0.037 Tc (-1)Tj 10.08 0 0 10.08 177.24 186.48 Tm 0.008 Tc 0.099 Tw [(\))8(,)20( )24(i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(i)24(n)8(g)8( )24(t)24(h)-16(e)23( s)16(c)23(at)24(te)23(r)8(i)24(n)-16(g)32( c)23(o)32(n)-16(t)24(r)8(a)0(s)16(t)0( o)32(f)31( t)24(h)-16(e)23( t)24(u)8(mo)32(r)8( p)32(r)-16(e)23(f)31(e)23(r)-16(e)23(n)8(ti)24(ally)56( e)23(n)8(h)8(a)23(n)-16(c)23(e)23(s)16( e)23(d)8(g)8(e)]TJ -5.9286 -1.1429 TD 0.171 Tw [(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( f)31(o)32(r)-16( s)16(m)24(al)24(l b)56(r)-16(e)23(a)0(s)16(t)0( s)40(ize)23(s)16(,)20( w)40(h)-16(i)24(l)0(e)23( i)24(m)0(p)32(r)-16(o)32(v)32(i)0(n)-16(g)32( s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56( f)8(o)32(r)-16( l)24(a)23(r)-16(g)8(e)47(r)-16( b)56(r)-16(e)23(a)0(s)16(t)24( s)16(ize)23(s)16(.)20( T)24(h)-16(is)]TJ T* 0.009 Tc 0.003 Tw [(d)9(i)1(f)32(f)9(e)24(r)-15(e)24(n)9(ti)25(al)25( r)-15(e)24(s)17(p)9(o)33(n)-15(s)17(e)24( )-24(is)17( mo)33(s)17(t)1( n)-15(o)33(tic)24(e)24(a)1(b)33(l)1(e)24( )-24(f)9(o)33(r)-15( )-24(b)33(r)-15(e)24(a)1(s)41(t)1(s)17( )-24(c)24(o)33(n)-15(t)25(ai)25(n)9(i)25(n)-15(g)9( l)25(a)24(r)-15(g)9(e)48(r)-15( tu)9(mo)57(r)-15(s)17(.)21( )-24( )-24(R)33(e)24(s)17(u)9(lts)17( i)25(n)-15( )-48(P)41(a)24(n)-15(e)24(l)]TJ 0 -1.119 TD 0.027 Tw [(\()9(b)33(\))9( )24(s)17(h)-15(o)33(w)41( )24(th)9(at)25( )24(t)25(h)-15(e)24( s)17(e)48(n)-15(s)17(i)25(tiv)33(ity)57( e)24(n)9(h)-15(a)24(n)-15(c)24(e)24(m)1(e)48(n)-15(t)25( s)17(e)24(e)24(n)-15( )24(i)25(n)-15( )24(la)24(r)9(g)9(e)24( b)33(r)-15(e)24(a)1(s)17(t)1(s)41( w)41(h)-15(e)24(n)9( t)25(h)-15(e)48( s)17(c)24(atte)48(r)-15(i)25(n)9(g)9( c)24(o)33(n)9(t)25(r)-15(a)1(s)17(t)25( o)33(f)]TJ 0 -1.1429 TD 0.008 Tc 0.052 Tw [(t)24(h)-16(e)23( tu)32(mo)32(r)8( is)40( i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(e)23(d)8( is)40( c)23(o)32(mp)8(le)23(te)23(ly)56( ab)8(o)32(lis)16(h)-16(e)23(d)8( u)8(p)8(o)56(n)-16( )24(i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(i)0(n)8(g)32( t)24(h)-16(e)23( )24(ab)32(s)16(o)32(r)-16(p)8(tio)56(n)-16( )-23(c)23(o)32(n)-16(t)24(r)8(a)0(s)16(t)24( )-23(o)32(f)31( )-23(th)-16(e)]TJ T* [(tu)8(mo)32(r)8( to)32( 0)32(.)-4(2)32( c)23(m)]TJ 6.48 0 0 6.48 183 133.406 Tm 0 Tc (-1)Tj 10.08 0 0 10.08 188.28 129.12 Tm -0.015 Tc 0.075 Tw [(.)-27( )24( )24(Th)-39(i)-23(s)17( s)17(h)-39(o)9(w)-7(s)-7( th)-39(at)-23( u)9(n)-15(d)-15(e)0(r)-15( th)-39(e)24( co)9(n)-39(d)-15(i)-23(t)1(i)-23(o)9(n)-39(s)17( ex)-15(a)-23(min)-39(ed)-15(, a )-23(f)8(o)9(u)-15(r)-39(\226)-15(f)8(o)9(l)-23(d)-15( )-23(en)-15(h)-39(a)0(n)-39(cem)-23(e)24(n)-39(t)]TJ 7.92 0 0 7.92 146.52 460.252 Tm -0.008 Tc 0.001 Tw [( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( \()-8( a)-19( \))-39( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )-30( )]TJ 32.3919 0 TD 0 Tc 0.023 Tw [( \( b)15( )31(\))]TJ -32.3919 -1.1515 TD -0.019 Tc 0.072 Tw [(F)-8(i)-14(g)-34(.)-11( )30(6)-34(.)-11( )30(E)-44(F)-8(W)-14(H)-55(M)-9( v)-34(e)1(r)-50(s)6(u)-34(s)-24( )30(\()-19(a)-30(\))-19( )30(t)-44(h)-34(e cr)-50(o)-34(s)-24(s\226)-34(s)-24(e)-30(ct)-14(i)-44(o)-34(na)-30(l)-14( a)-30(r)-50(ea)-30( r)-19(a)-30(t)-14(i)-44(o )-30(f)-19(o)-4(r)-19( )-30(di)-44(f)-19(f)-19(e)1(r)-50(e)-30(nt)-14( )-30(br)-50(ea)-60(st)-14( )-30(di)-14(a)-60(m)-29(et)-44(er)-50(s a)-60(n)-4(d)-34( \()-19(b)-34(\))-19( t)-44(h)-34(e )-30(br)-19(ea)-60(s)-24(t)]TJ T* -0.017 Tc 0.252 Tw [(di)-12(a)-58(m)3(e)-28(t)-12(e)-28(r)-17( f)-17(o)-2(r)-17( di)-42(f)-17(f)-17(e)3(r)-48(e)-28(nt)-12( cr)-48(o)-32(s)-22(s)8(\226)-32(s)-22(e)-28(ct)-12(i)-42(o)-32(na)-28(l)-12( )30(a)-28(r)-48(ea)-28( )30(r)-17(a)-28(t)-12(i)-42(o w)-22(i)-12(t)-42(h)-2( )30(C)-17(a)-58(s)-22(e)3( )30(1)-32( ba)-28(ck)-62(gr)-17(ou)-62(nd)-32( med)-32(i)-12(u)-62(m )30(a)-58(n)-2(d)-32( )30(C)-17(a)-58(s)8(e)-28( 3)-32( t)-12(u)-62(mor)]TJ 0 -1.2121 TD 0.013 Tc -0.021 Tw [(c)33(o)-2(n)28(t)18(r)13(a)-28(s)8(t)18( at)18( 180)]TJ /F12 1 Tf 5.9394 -0.0217 TD 0 Tc 0 Tw (\260)Tj /F5 1 Tf 0.3939 0.0217 TD 0.015 Tc -0.023 Tw [( )-31(v)30(i)-10(ew)40( ang)30(l)-10(e)35(.)-8( D)-21(e)4(f)45(i)-10(n)30(i)20(t)20(i)-10(on)30( )-31(of)45( )-31(s)10(y)0(m)35(b)0(o)30(l)-10(s)10( i)-10(s)40( )-31(g)30(i)-10(ve)35(n i)-10(n)30( Fi)20(g.)23( 5.)]TJ ET q 184.08 0 0 -142.56 121.08 613.44 cm /Im6 Do Q q 193.68 0 0 -142.32 307.08 613.44 cm /Im7 Do Q endstream endobj 49 0 obj << /ProcSet [/PDF /Text /ImageC /ImageI] /Font << /F5 5 0 R /F7 6 0 R /F12 26 0 R >> /XObject << /Im6 43 0 R /Im7 45 0 R >> /ExtGState << /GS1 8 0 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i)24(n)8(h)-16(o)32(mo)32(g)8(e)23(n)-16(e)23(o)32(u)8(s)16( b)32(a)0(c)23(k)8(g)8(r)-16(o)32(u)32(n)-16(d)32( me)23(d)8(i)0(u)32(m)24( \()]TJ /F7 1 Tf 35.9762 -0.052 TD -0.016 Tc [(i.)-28(e)]TJ /F5 1 Tf 0.9762 0.052 TD -0.012 Tc (.,)Tj -36.9524 -1.1429 TD -0.024 Tc 0.179 Tw [(C)-24(a)-32(s)-16(e)-9( 6)-24( ba)-32(c)-9(k)-24(gr)-48(oun)-48(d)-24(\))-24(.)-12( )24( A)-16( s)-16(i)-8(m)-32(i)-8(l)-32(a)-9(r)-24( pl)-32(ot)-32( for)-48( t)-8(h)-48(e)-9( )24(h)-48(o)0(m)-32(o)0(g)-24(e)-9(n)-48(e)-9(ou)-24(s)-16( ba)-32(c)-9(k)-24(g)-24(r)-48(oun)-48(d c)-9(a)-32(s)-16(e)-9( )-24(w)8(a)-32(s)-16( )-24(s)-16(h)-48(ow)8(n)-48( )-24(i)-8(n)]TJ T* 0.009 Tc 0.027 Tw [(F)17(i)1(g)9(u)33(r)-15(e)24( )24(4)33(.)-3( )24( C)9(o)33(mp)9(a)24(r)9(is)17(o)33(n)9( )24(r)-15(e)24(v)33(e)24(als)17( t)25(h)-15(a)24(t)1( w)41(h)-15(e)48(r)-15(e)24(a)1(s)41( t)25(h)-15(e)24( e)24(d)9(g)9(e)24( )24(r)-15(e)24(s)17(o)33(lu)9(tio)57(n)-15( )24(als)17(o)33( i)25(m)1(p)33(r)-15(o)33(v)33(e)24(s)17( )-24(w)41(ith)9( i)25(n)-15(c)48(r)-15(e)24(a)1(s)17(i)25(n)-15(g)]TJ 0 -1.119 TD 0 Tc 0.107 Tw [(b)24(r)-24(e)15(a)-8(s)8(t)-8( s)8(i)16(z)-8(e)15(,)12( i)-8(t)-8(s)32( a)15(ngul)16(a)15(r)-24( )24(de)15(pe)15(n)-24(d)0(e)39(n)-24(c)15(e)15( i)-8(s)8( )24(n)-24(o)24(t)16( a)15( s)8(i)-8(m)16(p)0(l)-8(e)15( f)23(u)24(n)-24(c)15(t)-8(i)-8(o)24(n )-24(o)24(f)23( )-24(b)24(r)-24(e)15(a)-8(s)8(t)-8( )-24(s)8(i)16(z)-8(e)15(.)-12( )-24(T)16(h)0(i)-8(s)8( a)-8(b)24(s)8(e)15(n)-24(c)15(e)15( )-24(of)]TJ 0 -1.1429 TD 0.008 Tc 0.099 Tw [(li)24(n)-16(e)23(a)23(r)8( s)16(c)23(ali)24(n)8(g)8( b)32(e)23(tw)40(ee)23(n)-16( )24(me)23(as)16(u)32(r)-16(e)23(d)8( )24(r)-16(e)23(s)16(p)8(o)32(n)-16(s)16(e)23( a)23(n)8(d)8( )24(ta)23(r)8(g)8(e)23(t g)8(e)23(o)32(m)0(e)23(t)24(r)-16(y)56( c)23(a)0(n)-16( )-24(b)32(e)23( )-24(s)16(e)23(e)23(n)-16( mo)32(r)-16(e)23( )-24(c)23(l)0(e)23(a)23(r)-16(ly)56( )-24(b)8(y)]TJ T* 0.194 Tw [(c)23(o)32(mp)8(ar)8(i)24(n)-16(g)8( )23(t)24(h)-16(e)23( s)16(e)47(n)-16(s)16(it)24(iv)32(itie)23(s)16( o)32(b)32(s)16(e)23(r)-16(v)8(e)23(d)8( at)24( 1)8(8)8(0)32(\260 )23(a)23(n)-16(d)32( at)24( 2)8(0)32(0)8(\260)27(, )23(as)16( a f)31(u)32(n)-16(c)23(t)24(i)0(o)32(n)8( o)32(f)31( th)-16(e)23( c)23(o)32(mp)8(o)32(s)16(ite)]TJ ET 1 1 1 rg 1 i 137.88 458.64 172.8 -43.2 re f* BT 7.92 0 0 7.92 145.08 448.012 Tm 0 0 0 rg 0.015 Tc 0.068 Tw [(F)26(i)20(g.)23( )30(8.)23( Pe)35(r)-16(c)35(en)30(t)-10( c)35(h)30(a)-26(n)30(ge)35( i)20(n)0( )-31(s)40(e)4(ns)40(i)-10(t)20(i)-10(v)30(i)20(t)-10(y)30( )-31(v)30(e)4(r)-16(s)40(us)10( v)30(i)-10(ew)]TJ 0 -1.1818 TD -0.016 Tc 0.372 Tw [(a)-27(ngl)-41(e)-27( )-30(f)14(o)-1(r)-47( d)-31(i)-41(f)-16(f)-16(e)4(r)-47(e)4(nt)-41( ba)-57(ck)-31(gr)-47(ou)-31(n)-31(d)-1( )-30(m)-26(e)-27(di)-11(a)-27( )-30(w)-21(i)-11(t)-11(h)-31( a)]TJ 0 -1.1515 TD -0.018 Tc 0.101 Tw [(br)-49(ea)-29(s)-23(t)-13( s)7(i)-43(z)-29(e)2( o)-33(f)12( )]TJ /F7 1 Tf 5.7576 -0.0217 TD 0 Tc 0 Tw (d)Tj /F5 1 Tf 0.5152 0.0217 TD 0.013 Tc 0.101 Tw [( )31(= )31(16 cm)33(,)21( t)18(u)-2(mo)28(r)13( s)38(i)-12(ze)33( of)43( )]TJ /F7 1 Tf 10.2727 -0.0217 TD 0 Tc 0 Tw (r)Tj /F5 1 Tf 0.4242 0.0217 TD 0.014 Tc 0.069 Tw [( = 0.)22(25)]TJ -16.9697 -1.1515 TD 0 Tc -0.008 Tw [(%)15(,)8( a)-41(n)-15(d)15( Ca)-41(se)20( 1)-15( tu)-45(m)-10(o)15(r )-31(c)20(o)-15(n)15(t)5(ra)-41(s)25(t)-25(.)]TJ ET 1 1 1 rg 333.96 458.64 180 -42.72 re f* BT 7.92 0 0 7.92 341.16 448.012 Tm 0 0 0 rg 0.015 Tc 0.22 Tw [(F)26(i)20(g.)23( )61(9.)23( )30(Pe)35(r)-16(c)35(en)30(t)-10( c)35(h)30(a)-26(n)30(ge)35( i)20(n)0( s)40(e)4(ns)40(i)-10(t)20(i)-10(v)30(i)20(t)-10(y)30( v)30(e)4(r)-16(s)40(us)10( )30(v)30(i)-10(ew)]TJ 0 -1.1818 TD -0.024 Tc 0.107 Tw [(a)-35(n)-9(g)-9(l)-49(e)-35( )-31(fo)-9(r)-55( d)-39(i)-49(f)-24(f)-24(e)-4(r)-55(e)-4(n)-9(t)-49( b)-39(r)-24(ea)-65(st)-49( )-31(si)-49(ze)-35(s)-29(,)-16( )-31(wi)-49(t)-19(h)-39( C)-24(a)-65(se)-35( 3)-39( )-31(t)-19(u)-69(mo)-9(r)]TJ 0 -1.1515 TD -0.001 Tc 0.266 Tw [(c)19(o)-16(n)14(t)4(ra)-42(st )30(a)-12(n)-16(d)14( tu)-16(m)-11(o)14(r s)24(i)-26(z)-12(e)19( o)-16(f)29( )]TJ /F7 1 Tf 11.9091 -0.0217 TD 0 Tc 0 Tw (r)Tj /F5 1 Tf 0.4242 0.0217 TD 0.013 Tc 0.222 Tw [( =1%)28(,)-10( embe)33(dded)28( i)-12(n)]TJ -12.3333 -1.1515 TD 0.003 Tc -0.011 Tw [(Ca)-8(se)23( 6)-12( )-31(b)18(a)-8(c)23(k)]TJ ET q 341.16 419.52 165.6 35.52 re W n BT 7.92 0 0 7.92 379.797 420.412 Tm 0 Tc 0 Tw (g)Tj ET Q BT 7.92 0 0 7.92 383.636 420.412 Tm 0.045 Tc -0.022 Tw [(r)45(o)60(un)60(d)30( m)65(e)34(d)60(i)50(um)]TJ ET q 200.4 0 0 -143.28 317.88 606.72 cm /Im11 Do Q 424.44 595.2 m 423.96 595.68 l 423.72 595.44 l 423.96 595.2 l 424.44 595.2 l f 424.44 594 m 424.44 594.24 l 424.2 594.48 l 423.96 594.48 l 423.72 594.24 l 423.72 594 l 423.96 593.76 l 424.44 593.76 l 424.44 594 l f 424.44 592.56 m 424.44 592.8 l 424.2 593.04 l 423.96 593.04 l 423.72 592.8 l 423.72 592.56 l 423.96 592.32 l 424.44 592.32 l 424.44 592.56 l f 424.44 591.12 m 424.44 591.36 l 424.2 591.6 l 423.96 591.6 l 423.72 591.36 l 423.72 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0 2.143 10.08 137.88 636.24 Tm 0 Tw ( )Tj /F7 1 Tf 10.08 0 0 10.08 153.48 636.196 Tm 0.012 Tw [(Inf)-8(l)-8(u)24(e)-8(n)24(c)-8(e)15( of)16( Sour)32(c)-8(e)15( L)8(o)0(c)-8(a)24(t)-8(i)-8(o)24(n)]TJ /F5 1 Tf -3.5714 -1.6861 TD 0.274 Tw [(T)16(h)-24(e)15( )24(r)-24(e)15(s)8(u)0(l)-8(t)-8(s)32( i)16(n)0( F)8(i)-8(gu)24(r)-24(e)15(s)8( )24(11\(a)15(\) )24(a)15(n)-24(d)24( 11\(b)24(\) s)32(h)-24(o)24(w)32( t)-8(h)-24(e)15( de)15(pe)39(n)-24(d)0(e)39(n)-24(c)15(e)15( of)23( t)16(h)-24(e)15( m)16(a)-8(xi)16(m)-8(u)24(m)-8( )24(de)15(t)-8(e)15(c)15(t)-8(o)24(r)]TJ 0 -1.1429 TD 0.008 Tc 0.099 Tw [(s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56( to)32( th)-16(e)23( )24(tu)8(mo)56(r)-16( o)56(n)-16( s)16(o)32(u)8(r)-16(c)23(e)23( )-24(lo)32(c)23(atio)56(n)-16( )-24(\()8(0)32(\260 )]TJ /F7 1 Tf 19.619 -0.052 TD [(vs)16(.)]TJ /F5 1 Tf 1.0714 0.052 TD 0.007 Tc 0.124 Tw [( -)7(4)7(0)31(\260\))7(,)19( as)39( a)22( f)30(u)7(n)-17(c)22(t)23(i)-1(o)31(n)7( o)31(f)30( th)-17(e)22( )24(tu)7(mo)55(r)-17( c)46(r)-17(o)31(s)15(s)15(\226)]TJ -20.6905 -1.1429 TD -0.015 Tc 0.146 Tw [(s)-7(ect)-23(i)-23(o)9(n)-39(a)-23(l ar)-39(ea )24(r)-39(a)0(t)-23(i)-23(o)9( )24(an)-39(d)-15( )24(th)-39(e b)9(r)-39(ea)-23(s)17(t)-23( d)9(i)-23(am)-23(et)-23(e)24(r)-39(, f)8(o)9(r)-39( b)9(a)-23(ck)-15(g)-15(r)-39(o)9(u)9(n)-39(d)9( m)-23(e)0(d)-15(i)-23(u)9(m)1( 6)-15(.)-3( )24(Th)-39(i)-23(s)17( )-24(co)9(m)-23(p)-15(ar)-39(i)-23(s)-7(o)9(n)-15( )-24(i)-23(s)]TJ T* 0.008 Tc 0.123 Tw [(mad)8(e)23( )48(to)32( )24(mo)32(d)8(e)23(l )48(h)-16(o)32(w)40( )24(th)-16(e)47( s)16(o)32(u)8(r)-16(c)23(e)23( lo)32(c)23(atio)32(n)8( i)24(n)-16(f)31(l)0(u)8(e)47(n)-16(c)23(e)23(s)16( t)24(h)-16(e)23( e)23(x)8(p)8(e)23(c)23(t)0(e)23(d)8( s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56( o)8(f)31( me)23(as)16(u)8(r)-16(e)23(m)0(e)47(n)8(t)]TJ T* 0.009 Tc 0.027 Tw [(f)9(o)33(r)-15( )48(a)24(n)-15( )48(i)25(n)9(h)-15(o)33(mo)33(g)9(e)24(n)-15(e)24(o)33(u)9(s)17( )24(me)24(d)9(i)1(u)33(m)1(,)21( )24(as)41( )24(a)24( f)32(u)9(n)-15(c)24(tio)57(n)-15( o)33(f)32( t)25(h)-15(e)24( c)24(o)33(mp)9(o)33(s)17(ite)24( ta)24(r)9(g)9(e)24(t g)9(e)24(o)33(m)1(e)24(t)25(r)-15(y)57(. I)32(n)-15(s)17(p)9(e)24(c)24(tio)33(n)9( o)33(f)]TJ T* 0.008 Tc 0.123 Tw [(t)24(h)-16(e)23( f)31(i)0(g)8(u)32(r)-16(e)23( )24(r)-16(e)23(v)32(e)23(als)16( t)24(r)-16(e)47(n)-16(d)8(s)16( s)16(i)24(mi)24(la)23(r)8( )24(to)32( t)24(h)-16(o)32(s)16(e)23( o)8(b)32(s)16(e)23(r)-16(v)8(e)23(d)8( i)24(n)-16( F)40(i)0(g)8(u)32(r)-16(e)23( )-24(1)8(0)32(.)20( )-24( T)24(h)-16(u)8(s)16(,)20( )-24(w)40(h)-16(e)47(r)-16(e)23(a)0(s)16( it)24( )-24(is)16( to)32( )-24(b)32(e)]TJ T* 0.29 Tw [(e)23(x)8(p)8(e)23(c)23(t)0(e)23(d)8( )24(th)8(at)24( v)32(a)0(r)-16(y)56(in)-16(g)32( t)24(h)-16(e)47( s)16(o)32(u)8(r)-16(c)23(e)23( p)8(o)32(s)16(itio)32(n)8( c)23(a)23(n)8( i)24(n)-16(f)31(l)0(u)8(e)47(n)-16(c)23(e)23( me)23(as)16(u)32(r)-16(e)23(m)0(e)47(n)-16(t)24( s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56( f)8(o)32(r)-16( )24(a)23(n)]TJ T* -0.024 Tc 0.345 Tw [(i)-8(n)-24(h)-48(o)0(m)-32(o)0(g)-24(e)-9(n)-48(e)-9(ou)-24(s)-16( )23(m)-32(e)-9(d)-24(i)-32(u)-24(m)-8(,)-36( )23(w)8(h)-24(a)-32(t)-8( i)-32(s)8( )23(n)-48(o)0(t)-32( obvi)-56(ou)-24(s)-16( i)-32(s)-16( t)-8(h)-24(a)-32(t)-8( t)-8(h)-48(e)-9( )23(m)-8(a)-32(g)-24(n)-24(i)-8(t)-32(u)-24(d)-24(e)-9( of t)-8(h)-48(e)-9( d)-24(i)-32(ffe)-9(r)-48(e)-9(n)-48(t)-8(i)-32(a)-9(l)]TJ T* 0.008 Tc 0.075 Tw [(r)-16(e)23(s)16(p)8(o)32(n)-16(s)16(e)23( )23(is)40( )23(its)16(e)23(l)0(f)31( )23(d)8(e)23(p)8(e)23(n)8(d)8(e)23(n)8(t)0( )23(o)56(n)-16( )47(t)24(h)-16(e)23( )23(c)23(o)32(mp)8(o)32(s)16(ite)23( )23(ta)23(r)-16(g)8(e)23(t)24( g)8(e)23(o)32(m)0(e)23(t)24(r)-16(y)56(. T)24(h)-16(e)23( f)31(o)32(r)-16(m)24( o)32(f)31( th)8(is)16( d)8(e)23(p)8(e)47(n)-16(d)8(e)47(n)-16(c)23(e)]TJ T* [(r)-16(e)23(v)32(e)23(als)16( )23(a)23(n)8( ab)32(s)16(e)23(n)-16(c)23(e)23( o)32(f)31( s)16(c)23(alin)8(g)8( )23(i)24(n)-16( s)16(e)47(n)-16(s)16(it)24(iv)32(ity)56( as)16( a)23( f)31(u)8(n)-16(c)23(tio)56(n)-16( o)32(f)31( c)23(o)32(mp)8(o)32(s)16(ite)23( ta)23(r)-16(g)8(e)23(t)0( g)8(e)23(o)32(m)0(e)23(t)24(r)-16(y)56(, e)23(v)8(e)23(n)]TJ 0 -1.119 TD 0 Tc 0.012 Tw [(t)16(h)-24(o)24(ugh i)-8(d)0(e)39(n)0(t)-8(i)-8(c)15(a)-8(l)16( b)24(a)-8(c)15(k)0(g)24(r)-24(o)24(u)0(n)-24(d)24( s)8(t)16(r)-24(u)0(c)15(t)16(u)24(r)-24(e)15(s)8( a)15(r)-24(e)15( p)24(r)-24(e)15(s)8(e)39(n)-24(t)16(.)]TJ 0 -22.6429 TD [(3.)-12(2.)-12(4)]TJ /F9 1 Tf 2.0238 -0.0823 TD 0 Tw ( )Tj /F7 1 Tf 1.5476 0.0303 TD 0.393 Tw [(Com)8(par)8(i)-8(s)8(on)24( of)16( Se)15(ns)8(i)-8(t)16(i)-8(v)15(i)-8(t)16(y)-8( D)32(e)-8(pe)-8(n)24(d)0(e)-8(n)24(c)-8(e)15( )-24(of)16( )-24(M)23(R)-8(I)23( )-24(B)-8(r)8(e)15(a)0(s)8(t)-8( Map)24( )-24(t)-8(o)0( H)8(o)0(m)8(o)0(g)24(e)-8(ne)-8(o)24(u)0(s)]TJ 0 -1.1429 TD [(B)-8(a)0(c)15(k)-8(gr)8(ound)]TJ /F5 1 Tf -3.5714 -1.6861 TD 0.298 Tw [(R)24(e)15(s)8(u)0(l)-8(t)-8(s)8( )24(i)-8(n)0( )24(F)8(i)16(gu)24(r)-24(e)15(s)8( 8\22611)24( i)16(d)0(e)15(n)0(t)-8(i)-8(f)23(i)-8(e)15(d t)16(h)-24(e)39( s)8(e)15(n)-24(s)8(i)16(t)-8(i)-8(v)24(i)-8(t)-8(y)48( de)15(pe)15(n)-24(d)0(e)15(n)-24(c)15(i)-8(e)15(s)8( o)24(f)23( v)24(a)-8(r)-24(i)-8(o)24(u)0(s)8( )24(m)-8(e)15(a)-8(s)8(u)24(r)-24(e)15(m)-8(e)15(n)0(t)]TJ 0 -1.1429 TD 0.107 Tw [(c)15(o)24(n)-24(f)23(i)-8(gur)-24(a)15(t)-8(i)-8(o)48(n)-24(s)8( )24(f)23(o)24(r)-24( )24(a)15( )24(f)23(i)-8(xe)15(d )24(s)8(t)16(ruc)15(t)-8(u)24(r)-24(a)15(l)-8( )47(h)-24(e)15(t)-8(e)39(r)-24(o)24(ge)15(n)-24(e)15(i)-8(t)-8(y)48(,)-12( a)-8(s)32( a)15( f)23(u)0(n)-24(c)15(t)16(i)-8(o)24(n)-24( o)24(f)23( b)24(a)-8(c)15(kgr)-24(o)24(u)24(n)-24(d c)15(o)24(nt)16(r)-24(a)-8(s)8(t)16( a)15(n)0(d)]TJ T* 0.008 Tc 0.29 Tw [(c)23(o)32(mp)8(o)8(s)16(ite)23( ta)23(r)8(g)8(e)23(t g)8(e)23(o)32(m)0(e)23(t)24(r)-16(y)56(. To)32( c)23(o)32(mp)8(le)23(te)23( o)32(u)8(r)8( u)32(n)-16(d)8(e)47(r)-16(s)16(t)24(a)23(n)-16(d)8(i)24(n)8(g)8(,)20( i)24(t)0( )24(is)16( u)8(s)16(e)23(f)31(u)8(l)0( to)32( )24(is)16(o)32(late)23( )-23(t)24(h)-16(e)]TJ T* 0.024 Tc 0.297 Tw [(i)40(n)0(f)47(l)16(u)24(e)39(nc)39(e)39( o)48(f)47( s)32(t)16(ru)24(c)39(t)16(u)48(r)24(a)16(l)40( )23(he)39(t)16(e)39(ro)48(g)24(e)63(ne)39(i)16(t)16(y)72( )]TJ /F7 1 Tf 15.8809 -0.052 TD -0.008 Tc 0.329 Tw [(p)-8(e)-16(r se)]TJ /F5 1 Tf 2.7143 0.052 TD 0.009 Tc 0.336 Tw [(. )47( )24(T)25(h)9(is)17( w)41(a)1(s)17( i)25(n)-15(v)33(e)24(s)17(tig)33(ate)24(d)9( b)33(y)57( co)33(mp)9(ar)9(i)25(n)-15(g)33( t)25(h)-15(e)]TJ -18.5952 -1.1429 TD 0 Tc 0.083 Tw [(m)-8(e)15(a)-8(s)8(u)24(r)-24(e)15(d)0( )47(r)-24(e)15(s)8(p)0(o)24(n)-24(s)8(e)15(s)8( f)23(o)24(r)-24( t)16(h)-24(e)15( c)15(a)-8(s)8(e)15( 6)24( b)24(a)-8(c)15(k)0(g)24(r)-24(o)24(u)0(n)-24(d)24( t)-8(o)24( )23(a)-8( )23(h)-24(o)24(m)-8(o)24(ge)15(n)-24(e)15(o)24(u)0(s)8( b)24(a)-8(c)15(kgr)-24(o)24(und )23(m)-8(e)15(di)-8(u)24(m)-8( \(c)15(a)-8(s)8(e)]TJ T* 0.008 Tc 0.052 Tw [(1)8(\))8(,)-4( )24(as)16( )24(a f)31(u)32(n)-16(c)23(tio)56(n)-16( o)32(f)31( c)23(o)32(mp)8(o)8(s)16(ite)23( ta)23(r)8(g)8(e)23(t g)8(e)23(o)32(m)0(e)23(t)24(r)-16(y)56(, f)8(o)32(r)-16( a )-23(d)8(e)23(te)23(c)23(t)0(o)32(r)8( )-23(p)8(o)32(s)16(itio)32(n)-16(e)23(d)32( )-23(o)32(p)8(p)8(o)32(s)16(ite)23( )-23(t)24(h)-16(e)23( )-23(s)16(o)32(u)8(r)-16(c)23(e)23(.)]TJ T* 0.123 Tw [(F)16(i)0(g)8(u)32(r)-16(e)23( )24(1)8(2)32( )24(s)40(h)-16(o)32(w)40(s)16( )24(th)-16(e)23( )48(r)-16(e)23(s)16(u)8(lt)24( )24(f)31(o)32(r)-16( )24(t)24(h)-16(e)47( c)23(a)0(s)16(e)23( o)32(f)31( t)-24(y)56(p)8(e)23(-)8(3)8( tu)8(mo)32(r)8( c)23(o)32(n)-16(t)24(r)-16(a)0(s)40(t)0(.)20( )24(I)31(n)-16( P)40(a)23(n)-16(e)23(l )24(\()8(a)0(\))31(,)-4( w)40(e)23( s)16(e)23(e)23( th)8(at)]TJ T* 0.385 Tw [(c)23(o)32(mp)8(ar)-16(e)23(d)8( )24(to)32( t)24(h)-16(e)23( )24(h)-16(o)32(mo)32(g)8(e)23(n)-16(e)23(o)32(u)8(s)16( c)23(a)0(s)16(e)23(, t)24(h)-16(e)47( i)24(n)-16(f)31(l)0(u)8(e)47(n)-16(c)23(e)23( o)8(f)31( s)16(t)0(r)8(u)8(c)23(tu)32(r)-16(a)23(l h)-16(e)23(te)47(r)-16(o)32(g)8(e)23(n)-16(e)23(ity)56( )-24(o)32(n)-16( t)24(h)-16(e)]TJ 0 -1.119 TD 0.171 Tw [(d)8(e)23(te)23(c)23(tab)32(ility)56( o)8(f)31( th)-16(e)23( )24(tu)8(mo)56(r)-16( v)32(a)23(r)8(i)0(e)23(s)16( s)16(t)24(r)-16(o)32(n)-16(g)32(ly)56( )-23(w)40(ith)8( t)24(h)-16(e)47( b)32(r)-16(e)23(a)0(s)16(t)24( s)16(i)24(ze)23(. )-23(F)16(o)32(r)-16( )-23(s)40(m)0(a)23(ll\226)8(d)32(i)24(ame)23(te)47(r)-16( )-23(b)32(r)-16(e)47(a)0(s)16(t)]TJ 0 -1.1429 TD -0.015 Tc 0.17 Tw [(m)-23(a)-23(p)-15(s)17(,)-27( )48(th)-39(e )24(p)9(r)-39(es)-7(en)-39(ce )24(o)9(f)8( )24(a)-23(d)-15(d)-15(e)0(d)-15( )24(co)9(n)-39(t)1(r)-15(a)-23(s)-7(t)1( b)9(e)0(t)-23(w)-7(een)-39( th)-39(e p)9(a)0(r)-39(e)0(n)-39(c)24(h)-39(y)33(m)-23(a)-23( )24(an)-39(d)-15( )24(a)-23(d)9(i)-23(p)-15(o)9(s)-7(e t)-23(i)-23(s)-7(s)-7(u)-15(es)-7( r)-39(e)0(d)-15(u)-15(ces)]TJ T* 0.009 Tc 0.003 Tw [(s)17(e)24(n)-15(s)17(it)25(iv)33(ity)57( to)33( th)-15(e)24( )24(tu)9(mo)57(r)-15(.)21( H)41(o)9(w)41(e)1(v)33(e)24(r)-15(,)-3( t)25(h)-15(e)48( o)33(p)9(p)9(o)33(s)17(ite)24( e)24(f)9(f)9(e)24(c)24(t)1( is)17( s)17(e)24(e)24(n)-15( f)32(o)33(r)-15( )24(la)24(r)-15(g)9(e)48(r)9( )-24(d)9(i)25(ame)24(te)48(r)-15( )-24(b)57(r)-15(e)24(a)1(s)17(t)1(s)17(,)21( )-24(e)24(v)33(e)24(n)]TJ ET 1 1 1 rg 1 i 124.92 346.8 378 -56.4 re f* BT 12 0 0 12 132.12 336.515 Tm 0 0 0 rg 0.01 Tc 0 Tw [( )20( )20( )20( )20( )20( )20( )20( )20( )20( )20( )20( )20( )20( )20( )]TJ 7.92 0 0 7.92 219.24 336.172 Tm -0.008 Tc [(\()-8(a)-19(\))-8( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( )-31( \()-10(b)7(\))]TJ -11 -1.2121 TD 0.014 Tc 0.069 Tw [(F)25(i)19(g.)22( 11.)22( R)14(a)3(t)-11(i)19(o of)14( 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)48(a)23(r)-16(e)23( )24(n)-16(o)32(t s)16(i)24(n)8(g)8(l)0(e)23(\226)8(v)32(alu)8(e)23(d)8( f)31(u)32(n)-16(c)23(tio)56(n)-16(s)16(,)20( )24(r)-16(e)23(v)32(e)23(alin)8(g)8( )24(t)24(h)-16(a)23(t)0( )24(i)24(n)-16( )24(t)24(h)-16(e)23(s)16(e)23( c)23(a)0(s)16(e)23(s)16( max)32(im)24(u)8(m)24( s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56( is)]TJ 0 -1.1191 TD 0.075 Tw [(ac)23(h)8(i)0(e)23(v)32(e)23(d)8( at s)16(o)32(me)23( i)24(n)8(te)23(r)8(m)0(e)23(d)8(i)24(ate)23( b)32(r)-16(e)23(a)0(s)40(t)0( s)16(i)24(ze)23(.)20( A)40(l)0(s)16(o)32( d)8(i)0(f)31(f)8(e)23(r)-16(e)23(n)8(t )23(is)16( th)8(e)47( lo)32(s)16(s)16( o)32(f)31( e)23(d)8(g)8(e)23( )-24(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)-16( )-24(w)40(i)0(t)24(h)]TJ 0 -1.1428 TD 0.147 Tw [(i)24(n)-16(c)23(r)-16(e)23(a)0(s)16(i)24(n)8(g)8( )24(tu)32(mo)32(r)-16( s)40(ize)23(,)20( e)23(s)16(p)8(e)23(c)23(ially)56( in)8( t)24(h)-16(e)47( c)23(a)0(s)16(e)23( \()8(p)8(a)23(n)-16(e)47(l \()8(c)23(\))8(\))31( )-24(o)32(f)31( )-24(an)8( )-24(i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(e)23( )-24(i)24(n)8( t)24(h)-16(e)23( )-24(v)32(alu)8(e)23( )-24(o)32(f)31( )-24(t)24(h)-16(e)]TJ T* 0.123 Tw [(tu)8(mo)32(r)8( )24(ab)32(s)16(o)32(r)-16(p)8(tio)32(n)8( c)23(o)32(ef)8(f)31(i)0(c)23(i)0(e)23(n)-16(t.)20( )24(I)8(t)24( is)16( w)40(o)32(r)-16(t)24(h)8( )24(n)-16(o)32(ti)24(n)-16(g)32( t)24(h)8(at)24( )24(r)-16(e)23(s)16(u)8(lts)40( p)8(r)8(e)23(s)16(e)23(n)8(t)0(e)23(d)8( i)24(n)8( t)24(h)8(is)16( f)31(i)0(g)8(u)32(r)-16(e)23( d)8(o)32( n)-16(o)32(t)]TJ T* 0.147 Tw [(c)23(o)32(in)-16(c)23(i)0(d)8(e)23( w)40(ith)8( t)24(h)-16(e)47( p)8(o)32(s)16(itio)32(n)8( o)32(f)31( max)32(imu)32(m)24( s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56(, w)40(h)-16(ic)47(h)-16( )24(as)16( s)40(h)-16(o)32(w)40(n)-16( i)24(n)8( F)16(i)0(g)32(u)32(r)-16(e)23( 9)32(,)-4( o)32(c)23(c)23(u)8(r)-16(s)16( )24(at)]TJ T* 0 Tc 0.131 Tw [(~)-7(200\272)24( )24(f)23(r)-24(o)24(m)-8( )48(t)16(h)-24(e)15( )24(s)8(o)24(ur)-24(c)15(e)15(.)-12( )24( A)8( s)32(i)-8(m)16(i)-8(l)16(a)15(r)-24( )24(a)15(n)0(a)-8(l)-8(y)48(s)8(i)-8(s)8( a)-8(t)-8( )24(t)16(h)-24(i)-8(s)32( v)24(i)-8(e)15(w)32( a)-8(n)-24(g)24(l)-8(e)15( \()23(r)-24(e)15(s)8(ul)-8(t)-8(s)32( )24(n)-24(o)24(t)-8( s)32(h)-24(o)24(w)32(n)-24(\))0( p)24(r)-24(o)24(duc)15(e)15(d)]TJ T* 0.083 Tw [(t)16(r)-24(e)15(n)-24(ds)32( c)15(l)-8(o)24(s)8(e)15(r)-24( t)-8(o)24( t)16(h)-24(o)24(s)8(e)15( o)24(b)24(s)-16(e)15(r)-24(v)24(e)15(d fo)24(r)-24( a)15( )23(h)-24(o)24(m)-8(o)24(ge)15(n)-24(e)15(o)24(u)0(s)8( m)-8(e)15(di)-8(u)24(m)-8(.)12( )-24( )-24(T)16(h)0(i)-8(s)32( )-24(s)8(ugge)15(s)8(t)-8(s)8( t)16(h)-24(a)15(t)-8( )-24(b)24(a)-8(c)15(k)0(g)24(r)-24(o)24(u)24(n)-24(d)]TJ T* 0.024 Tc [(he)39(t)16(e)63(ro)48(g)24(e)39(ne)39(i)16(t)16(y)72( )]TJ /F7 1 Tf 5.9762 -0.052 TD -0.008 Tc 0.353 Tw [(p)-8(e)-16(r se)]TJ /F5 1 Tf 2.7381 0.052 TD 0.008 Tc 0.337 Tw [( d)8(o)32(e)23(s)16( n)-16(o)32(t f)31(u)32(n)-16(d)32(ame)47(n)-16(t)24(al)24(ly)56( limi)24(t )24(t)24(h)-16(e)23( ac)47(h)8(i)0(e)23(v)32(ab)32(le)23( )-24(e)23(d)8(g)8(e)23( )-24(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)-16( a)23(n)-16(d)]TJ -8.7143 -1.1429 TD 0.009 Tc 0.003 Tw [(s)17(e)24(n)-15(s)17(it)25(iv)33(ity)57(, b)33(u)9(t i)25(n)-15(s)17(t)1(e)24(a)1(d)33( a)24(lte)48(r)-15(s)17( )24(t)25(h)-15(e)24( lo)33(c)24(atio)57(n)-15( w)41(h)-15(e)48(r)-15(e)24( )24(t)25(h)-15(ey)57( c)24(a)1(n)9( b)33(e)24( att)25(ai)25(n)-15(e)24(d)33(.)]TJ /F7 1 Tf 0 -1.8853 TD 0 Tc [(3.)-12(2.)-12(6)]TJ /F9 1 Tf 10.08 0 2.143 10.08 137.88 554.64 Tm 0 Tw ( )Tj /F7 1 Tf 10.08 0 0 10.08 153.48 554.596 Tm -0.012 Tw [(R)-8(e)-8(s)8(pons)32(e)-8( t)-8(o)0( R)-8(e)15(duc)15(e)-8(d)24( )-24(Con)24(t)-8(r)8(as)8(t)-8( )-24(T)8(u)0(m)8(o)0(r)8(s)]TJ /F5 1 Tf -3.5714 -1.6861 TD -0.015 Tc 0.051 Tw [(Th)-39(e )48(r)-39(e)0(s)-7(u)-15(l)-23(t)-23(s)17( )24(p)9(r)-39(es)-7(en)-39(t)-23(e)0(d)9( )24(in)-15( )24(th)-39(e )48(p)9(r)-39(eced)-15(i)-23(n)-39(g)9( )24(f)8(i)-23(g)-15(u)9(r)-39(e)0(s)-7( em)-23(p)9(h)-15(a)-23(s)-7(i)-23(z)-23(e)0( )24(ma)-23(i)-23(n)-15(l)-23(y)33( th)-39(e in)-39(f)8(l)-23(u)-15(e)24(n)-39(ce th)-15(a)-23(t)1( th)-39(e v)9(a)0(r)-15(i)-23(o)9(u)-15(s)]TJ 0 -1.1429 TD 0.024 Tc 0.107 Tw [(p)24(a)39(ra)39(m)16(e)39(t)16(e)39(rs)56( )24(h)24(a)16(v)48(e)39( o)48(n)0( t)40(h)0(e)39( c)39(o)48(m)16(p)24(u)24(t)16(e)39(d)48( )24(re)39(s)32(p)24(o)48(n)0(s)32(e)39(s)32( f)47(o)48(r t)16(u)48(m)16(o)48(rs)32( )24(h)24(a)16(v)48(i)40(ng)24( c)39(o)48(n)24(t)40(ra)16(s)56(t)16( )-24(v)48(a)16(l)16(u)24(e)39(s)32( )-24(g)48(r)0(e)63(a)16(t)16(e)63(r t)40(h)0(a)39(n)]TJ T* -0.024 Tc 0.131 Tw [(t)-8(h)-48(os)-16(e)-9( o)-24(f)-1( t)-32(h)-48(e)-9( s)-16(u)0(r)-24(r)-48(oun)-48(di)-8(n)-48(g)-24( ba)-32(c)-9(k)-24(gr)-48(oun)-48(d)-24( )24(m)-32(e)-9(d)-24(i)-32(um)-32(.)-12( )24( In)-48( F)8(i)-32(g)-24(u)0(r)-48(e)-9( 14)-24( w)8(e)-9( e)-9(x)-24(a)-32(m)-32(i)-8(n)-48(e)15( )-24(t)-8(h)-48(e)-9( )-24(c)-9(o)0(r)-24(r)-48(e)-9(s)-16(p)-24(o)0(n)-48(d)0(i)-8(n)-48(g)]TJ T* 0.008 Tc 0.29 Tw [(r)-16(e)23(s)16(p)8(o)32(n)-16(s)16(e)23(s)16( f)31(o)32(r)-16( a)23( c)23(a)0(s)16(e)23( )-23(i)24(n)8( )-23(w)40(h)-16(ic)47(h)8( )-23(t)24(h)-16(e)23( i)24(n)-16(c)23(l)0(u)8(d)8(e)23(d)8( tu)32(mo)32(r)-16( is)16( mo)32(r)-16(e)23( )-23(w)40(e)23(ak)8(ly)56( )-23(s)16(c)23(atte)23(r)-16(i)24(n)8(g)8( t)24(h)-16(a)23(n)8( )-23(t)24(h)-16(e)]TJ T* -0.015 Tc 0.122 Tw [(b)9(a)-23(ck)-15(g)-15(r)-39(o)9(u)-15(n)-39(d)9(, )24(f)8(o)9(r)-39( )24(d)-15(i)-23(f)8(f)8(e)0(r)-39(e)0(n)-39(t)1( b)9(r)-39(ea)-23(s)-7(t)1( s)-7(i)1(z)-23(e)0(s)-7(,)-27( an)-15(d)-15( co)9(m)-23(p)-15(ar)-39(e)24( th)-15(i)-23(s)-7( t)-23(o)9( )24(th)-39(e )24(h)-39(o)9(m)-23(o)9(g)-15(e)0(n)-39(e)0(o)9(u)-15(s)-7( ca)-23(s)-7(e)0(.)-27( O)-7(v)9(er)-39(al)-23(l,)]TJ 0 -1.119 TD 0.008 Tc 0.147 Tw [(w)16(e)23( s)16(e)23(e)23( th)8(at)24( i)24(n)8( m)24(a)23(n)-16(y)56( c)23(a)0(s)16(e)23(s)16( a mo)32(r)-16(e)23( c)23(o)32(mp)8(le)23(x)32( p)32(r)-16(o)32(f)31(ile)23( is)16( o)32(b)32(s)16(e)23(r)-16(v)8(e)23(d)8(,)-4( t)24(h)-16(e)23( )24(t)24(r)-16(e)47(n)-16(d)8( )-24(f)31(a)0(v)32(o)32(r)-16(s)16( )-24(i)24(m)0(p)32(r)-16(o)32(v)32(e)23(d)]TJ 0 -1.1429 TD 0.009 Tc 0.003 Tw [(s)17(e)24(n)-15(s)17(it)25(iv)33(ity)57( an)-15(d)33( i)25(m)1(p)33(r)-15(o)33(v)33(e)24(d)9( e)24(d)9(g)9(e)24( d)9(e)24(te)24(c)24(tio)33(n)-15( w)41(ith)9( i)25(n)-15(c)48(r)-15(e)24(a)1(s)17(e)24(d)9( b)57(r)-15(e)24(a)1(s)17(t)1( s)41(ize)24(.)]TJ 7.92 0 0 7.92 210.84 324.652 Tm 0 Tc [(\(a)-11(\))]TJ 22.7273 -0.1818 TD [(\(b)15(\))]TJ -30.6667 -18.1515 TD 0.014 Tc 0.039 Tw [(F)25(i)19(g)29(u)-1(r)-17(e)34(14:)19( )30(Pe)34(r)-17(cen)29(t)19( ch)29(ange)34( )30(i)-11(n)29( s)9(e)3(ns)39(i)19(t)19(i)-11(v)29(i)-11(t)19(y)-1( )30(ve)34(r)-17(s)39(u)-31(s)39( v)29(i)-11(ew)39( )30(a)-27(n)29(gl)19(e f)44(o)29(r)-17( )30(di)-11(f)14(f)14(e)34(r)-17(e)34(nt)19( b)29(r)14(e)34(a)-27(s)39(t)-11( di)19(ame)34(t)-11(e)34(r)-17(s)9(,)22( )-30(w)39(i)-11(t)19(h)-1( c)34(a)-27(s)9(e)]TJ 0 -1.1818 TD -0.003 Tc -0.005 Tw [(8)-18( tu)-18(m)-13(o)12(r )-31(c)17(o)-18(n)12(t)2(ra)-44(s)22(t)-28( a)-14(n)-18(d)12( tu)-48(m)-13(o)12(r\226)-18(to)12(\226)-48(b)12(r)-34(e)17(a)-14(s)-8(t a)-14(r)-34(e)17(a)-14( ra)-14(ti)-28(o)12( )]TJ /F7 1 Tf 19.4545 -0.0217 TD 0 Tc 0 Tw (r)Tj /F5 1 Tf 0.4242 0.0217 TD 0.013 Tc -0.021 Tw [( = 1%)28(,)-10( )-31(e)33(m)3(bed)28(d)-2(ed)28( i)-12(n)28( \()13(a)2(\))-18( ho)28(mogen)28(e)2(o)28(u)-32(s)38(,)21( )-31(\()-18(b)28(\))-18( )-31(c)33(a)-28(s)8(e)33( )-31(4,)]TJ -19.8788 -1.1212 TD 0.014 Tc -0.022 Tw [(\()14(c)34(\))14( )-31(c)34(a)-27(s)9(e)34( 5 and)29( )-31(\()14(d)29(\))-17( c)34(a)-27(s)9(e)34( 8 )-31(b)29(a)-27(c)34(k)-1(g)29(r)-17(o)29(und)29( )-31(me)34(di)19(a,)22( r)-17(e)3(s)9(p)29(ec)34(t)-11(i)19(ve)34(l)-11(y)29(.)-9( T)-11(h)-1(e)34( l)-11(e)3(ge)34(nd)29( )-31(s)9(how)39(n app)29(l)19(i)-11(e)3(s)39( )-31(t)19(o)-1( al)19(l)19( )-31(p)29(a)-27(n)29(e)3(l)-11(s)39(.)]TJ ET q 171.36 0 0 -124.56 121.08 458.88 cm /Im22 Do Q q 171.36 0 0 -125.04 301.08 457.2 cm /Im23 Do Q q 171.36 0 0 -120 121.08 320.16 cm /Im24 Do Q q 171.36 0 0 -120 301.08 317.76 cm /Im25 Do Q BT 7.92 0 0 7.92 389.4 190.492 Tm 0 Tc [(\(d)15(\))]TJ -22.7273 0.2727 TD [(\(c)20(\))]TJ ET endstream endobj 96 0 obj << /ProcSet [/PDF /Text /ImageC /ImageI] /Font << /F5 5 0 R /F7 6 0 R /F9 7 0 R >> /XObject << /Im22 89 0 R /Im23 90 0 R /Im24 91 0 R /Im25 92 0 R >> /ExtGState << /GS1 8 0 R >> /ColorSpace << /CS3 34 0 R /CS5 44 0 R /CS11 93 0 R >> >> endobj 93 0 obj [/Indexed /DeviceRGB 7 97 0 R] endobj 97 0 obj << /Filter /ASCII85Decode /Length 30 >> stream s8W*!!!*$!!!*'!rrE'!!<3'!z~> endstream endobj 99 0 obj << /Length 19561 >> stream 1 1 1 rg /GS1 gs 21 -66 612 792 re f BT /F7 1 Tf 10.08 0 0 10.08 117.48 705.076 Tm 0 0 0 rg 0 Tc 0.012 Tw [(3.)-12(3)24( Sum)8(m)8(a)0(r)8(y)15( of)16( t)16(h)0(e)15( P)16(r)8(i)-8(n)0(c)-8(i)16(pal)16( R)16(e)-8(s)8(u)0(l)16(t)-8(s)]TJ /F5 1 Tf 0 -1.6861 TD -0.024 Tc 0.107 Tw [(A)-16(n)-24( i)-8(m)-32(p)-24(o)0(r)-24(t)-32(a)-9(n)-24(t)-32( ph)-48(e)15(n)-48(om)-32(e)15(n)-48(on)-24( obs)-40(e)-9(r)-48(ve)-9(d)-24( i)-32(n)-24( )-24(t)-8(h)-48(e)15( r)-48(e)-9(s)-16(u)-24(l)-32(t)-32(s)8( )-24(pr)-48(e)-9(s)-16(e)-9(n)-48(t)-32(e)-9(d )-24(i)-32(s)-16( t)-8(h)-48(a)-9(t)-32( )-24(for)-48( a)-9(n)-48(y)24( )-24(t)-32(u)-24(m)-32(o)0(r)-24(\226)-24(t)-32(o\226)-24(br)-48(e)-9(a)-32(s)-16(t)]TJ 0 -1.1429 TD 0.009 Tc 0.17 Tw [(a)24(r)-15(e)24(a)1( )48(r)9(a)1(t)25(i)1(o)33(,)-3( )24(t)25(u)9(mo)57(r)-15( )24(c)24(o)33(n)-15(t)25(r)9(a)1(s)17(t)25(, )48(a)24(n)-15(d)33( )24(b)33(a)1(c)24(k)9(g)33(r)-15(o)33(u)9(n)-15(d)33( me)24(d)9(i)25(u)9(m)25( c)24(o)33(n)-15(t)25(r)9(a)1(s)17(t)25(, t)25(h)-15(e)48( m)25(a)1(x)33(imu)33(m s)17(e)48(n)-15(s)17(i)25(tiv)33(ity)57( an)9(d)]TJ T* 0.008 Tc 0.266 Tw [(e)23(d)8(g)8(e)23( )24(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( )24(to)32( )48(t)24(h)-16(e)23( )24(i)24(n)-16(c)23(l)0(u)32(d)8(e)23(d)8( )24(t)24(u)8(mo)32(r)8( )24(b)32(o)32(t)0(h)8( i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(e)23( s)16(i)0(g)32(n)8(if)31(ic)23(an)8(tly)56( as)16( t)24(h)-16(e)47( b)32(r)-16(e)23(a)0(s)16(t)24( d)8(i)24(ame)23(te)47(r)]TJ T* -0.015 Tc 0.098 Tw [(in)-39(cr)-39(ea)-23(s)-7(e)0(s)-7(.)-3( )23( )23(A)-7(l)-23(s)-7(o)9( o)9(b)9(s)-7(er)-39(v)-15(e)0(d)-15( i)-23(s)-7( th)-15(a)-23(t)1( )23(in)-39(cr)-39(ea)-23(s)17(i)1(n)-39(g)-15( )23(t)-23(u)9(m)-23(o)9(r)-15( s)-7(i)-23(z)-23(e)0(, f)8(o)9(r)-39( a f)8(i)-23(x)-15(e)0(d)-15( tu)-15(m)-23(o)33(r)-39( co)9(n)-39(t)1(r)-15(a)-23(s)-7(t)1( an)-15(d)-15( b)33(r)-39(ea)-23(s)-7(t)]TJ 0 -1.119 TD 0.008 Tc 0.075 Tw [(s)16(ize)23(, )23(i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(e)23(s)16( s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56( to)32( th)-16(e)23( )23(tu)32(mo)32(r)8( a)23(n)-16(d)32(,)20( to)32( )-24(a)23( )-24(le)23(s)16(s)16(e)23(r)8( )-24(e)23(x)8(te)23(n)8(t)0(, i)24(t)0(s)16( r)-16(e)23(s)16(o)32(lu)8(tio)56(n)-16( )-24(\()]TJ /F7 1 Tf 31.2381 -0.052 TD -0.015 Tc (cf)Tj /F5 1 Tf 0.7143 0.052 TD 0 Tc 0.107 Tw [(.)12( F)32(i)-8(gu)24(r)-24(e)15(s)8( 6)24(,)-12( )24(7)]TJ -31.9524 -1.1429 TD 0.005 Tc 0.078 Tw [(a)20(n)-19(d )23(13\).)17( )23( I)28(n)5( add)29(i)-3(t)21(i)-3(o)29(n)5(,)-7( )23(i)21(n)-19(c)20(r)-19(e)20(a)-3(s)37(i)21(n)-19(g)29( ab)29(s)13(o)29(r)-19(p)5(tio)53(n)-19( c)20(o)29(nt)21(r)-19(a)-3(s)13(t)21( o)29(f)28( th)-19(e)44( tumo)53(r a)20(l)-3(o)29(n)-19(e)20( i)21(n)-19(c)44(r)-19(e)20(a)-3(s)13(e)20(s)13( )-24(s)13(e)20(n)-19(s)37(itiv)29(ity)53(,)]TJ T* 0.008 Tc 0.099 Tw [(b)32(u)8(t )24(d)8(o)32(e)23(s)16( n)-16(o)32(t i)24(m)0(p)32(r)-16(o)32(v)32(e)23( r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( \()]TJ /F7 1 Tf 13.6667 -0.052 TD -0.015 Tc (cf)Tj /F5 1 Tf 0.7143 0.052 TD 0.122 Tw [(. F)-7(i)-23(g)-15(u)9(r)-39(e)0(s)-7( )24(7)-15(,)-3( 1)-15(3)-15(\))8(.)-27( )24( We al)-23(s)-7(o)9( o)9(b)-15(s)-7(e)0(r)-39(v)9(ed)-15( t)-23(h)-15(a)-23(t)1( th)-39(e )24(in)-39(f)8(l)-23(u)-15(e)0(n)-39(ce o)9(f)]TJ -14.381 -1.1429 TD 0.008 Tc 0.194 Tw [(v)32(a)0(r)-16(y)56(in)-16(g)8( )47(t)24(h)-16(e)23( )23(s)16(c)23(at)24(te)23(r)8(i)24(n)-16(g)32( c)23(o)32(n)-16(t)24(r)8(a)0(s)16(t)0( o)32(f)31( t)24(h)-16(e)23( t)24(u)8(mo)32(r)8( o)32(n)8( s)16(e)23(n)-16(s)40(itiv)32(ity)56( a)23(n)-16(d)8( )23(r)-16(e)23(s)16(o)32(lu)8(t)24(i)0(o)32(n)8( is)16( )23(a)23( f)31(u)8(n)-16(c)23(tio)56(n)-16( o)32(f)]TJ T* 0.123 Tw [(c)23(o)32(mp)8(o)8(s)16(ite)23( )24(ta)23(r)8(g)8(e)23(t )24(s)16(i)24(ze)23( as)40( w)40(e)23(ll as)40( o)32(f)31( th)-16(e)23( )24(ab)32(s)16(o)32(r)-16(p)8(tio)32(n)8( c)23(o)32(n)-16(t)24(r)8(a)0(s)16(t)24( o)32(f)31( th)-16(e)23( )24(tu)8(mo)56(r)-16( \()]TJ /F7 1 Tf 30.0952 -0.052 TD -0.015 Tc (cf)Tj /F5 1 Tf 0.7143 0.052 TD 0 Tc 0.131 Tw [(.)12( F)32(i)-8(gu)24(r)-24(e)15(s)8( 7)24(,)-12( )24(13\).)]TJ -30.8095 -1.1429 TD 0.008 Tc 0.171 Tw [(F)16(o)32(r)-16( )24(s)16(m)24(all)24( )24(b)32(r)-16(e)23(a)0(s)40(t)0(s)16(,)20( )24(s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56( a)23(n)-16(d)8( )24(r)-16(e)23(s)16(o)32(lu)8(tio)56(n)-16( )24(a)23(r)-16(e)23( i)24(m)0(p)32(r)-16(o)32(v)32(e)23(d)8( s)16(imu)8(l)24(t)0(a)23(n)-16(e)23(o)32(u)8(s)16(ly)56( as)16( t)24(h)-16(e)23( s)16(c)23(atte)47(r)-16(i)24(n)8(g)]TJ T* 0.123 Tw [(c)23(o)32(n)-16(t)0(r)8(a)0(s)16(t)24( o)32(f)31( th)-16(e)23( )24(tu)8(mo)56(r)-16( )24(i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(e)23(s)16(,)-4( b)32(u)8(t )24(t)24(h)-16(e)23(r)-16(e)47( is)16( )24(a )24(la)23(r)8(g)8(e)23(r)8( c)47(h)-16(a)23(n)-16(g)8(e)23( o)32(f)31( s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56( f)8(o)32(r)-16( )-24(s)16(m)24(all)24( )-24(b)32(r)-16(e)23(a)0(s)40(t)0(s)]TJ T* 0.194 Tw [(w)40(ith)8( a)23( l)24(a)23(r)-16(g)8(e)23( t)24(u)8(mo)32(r)8(.)20( F)16(o)32(r)8( l)24(a)23(r)-16(g)8(e)23( b)56(r)-16(e)23(a)0(s)16(t)0(s)16( )23(t)24(h)-16(e)23( )23(r)-16(e)23(s)16(p)8(o)32(n)-16(s)16(e)23(s)16( o)32(f)31( e)23(d)8(g)8(e)23( r)-16(e)23(s)16(o)32(lu)8(tio)32(n)-16( )23(a)23(n)-16(d)32( s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56( )-24(is)]TJ T* 0.009 Tc 0.003 Tw [(d)9(i)1(f)32(f)9(e)24(r)-15(e)24(n)9(t,)21( s)17(u)9(c)24(h)9( t)25(h)9(a)24(t)1( )24(i)25(n)-15(c)24(r)-15(e)24(a)1(s)17(e)24(s)17( i)25(n)9( )24(t)25(h)-15(e)24( s)17(c)24(at)25(te)24(r)9(i)25(n)-15(g)33( c)24(o)33(n)-15(t)25(r)-15(a)1(s)41(t)1( o)33(f)32( t)25(h)-15(e)24( tu)33(mo)33(r)9( i)25(m)1(p)33(r)-15(o)33(v)33(e)24(s)17( )-24(s)17(e)24(n)-15(s)17(itiv)33(ity)57( )-24(alo)33(n)-15(e)24(,)]TJ T* 0.008 Tc 0.242 Tw [(b)32(u)8(t o)32(n)-16(ly)56( w)40(ith)-16( )24(tu)32(mo)32(r)-16(s)16( h)8(a)0(v)32(i)24(n)-16(g)8( mo)32(d)8(e)23(r)8(ate)23( ab)32(s)16(o)32(r)-16(p)8(tio)32(n)8( )-24(c)23(o)32(n)-16(t)24(r)8(a)0(s)16(t)0(.)20( )-24(I)8(n)8( al)24(l,)20( a )-24(c)23(o)32(n)-16(s)16(is)16(te)47(n)8(t)0( )-24(f)31(i)24(n)-16(d)8(i)24(n)8(g)]TJ T* 0.028 Tw [(t)24(h)8(r)-16(o)32(u)8(g)8(h)-16(o)32(u)8(t)24( )24(a)23(l)0(l)24( )24(t)24(h)-16(e)23( v)32(a)23(r)8(i)0(a)23(tio)32(n)-16(s)40( e)23(x)8(p)8(l)0(o)32(r)-16(e)23(d)32( is)16( )24(t)24(h)-16(e)23( )24(ab)32(s)16(e)23(n)-16(c)23(e)23( o)8(f)31( s)16(c)23(alin)-16(g)32( o)32(f)31( t)24(h)-16(e)23( me)23(as)16(u)32(r)-16(e)23(d)32( )24(r)-16(e)23(s)16(p)8(o)32(n)-16(s)16(e)23( w)40(i)0(t)24(h)]TJ T* 0.009 Tc 0.027 Tw [(ta)24(r)-15(g)9(e)24(t)25( s)17(ize)48(. )24( S)17(p)9(e)24(c)24(i)1(f)32(i)1(c)24(ally)57(, w)17(e)24( me)24(a)24(n)-15( )24(t)25(h)-15(a)24(t)1( )24(t)25(r)-15(e)48(n)-15(d)9(s)17( o)33(b)33(s)17(e)24(r)-15(v)33(e)24(d)9( in)9( e)24(d)9(g)9(e)24( r)-15(e)24(s)17(o)33(lu)9(tio)33(n)-15( a)24(n)-15(d)33( )-24(s)17(e)24(n)-15(s)41(itiv)33(ity)57( )-24(as)17( a)]TJ 0 -1.119 TD 0 Tc 0.036 Tw [(f)23(u)0(n)-24(c)15(t)-8(i)-8(o)24(n )24(o)24(f)23( )24(t)-8(u)0(m)-8(o)24(r )24(c)15(o)24(n)-24(t)16(ra)-8(s)8(t)-8(,)12( s)8(i)16(z)-8(e)15( a)15(nd b)24(a)-8(c)15(k)0(g)24(r)-24(o)24(und c)15(o)24(n)-24(t)16(ra)-8(s)8(t)16( do)24( n)-24(o)48(t)-8( e)15(x)0(t)16(r)0(a)-8(p)0(o)24(l)-8(a)15(t)-8(e)15( t)-8(o)24( m)-8(e)15(d)24(i)-8(a)15( o)24(f)23( l)-8(a)15(r)-24(g)0(e)15(r)]TJ 0 -1.1429 TD 0.083 Tw [(s)8(i)-8(z)-8(e)15(s)8(,)-12( e)15(v)24(e)15(n)-24( )23(t)16(h)-24(o)24(ugh t)16(h)-24(e)39( e)15(x)0(a)-8(c)15(t)-8( s)32(a)-8(m)-8(e)15( )23(di)-8(s)8(t)16(ri)-8(b)24(u)0(t)-8(i)-8(o)24(n o)24(f)23( i)-8(n)0(t)-8(e)15(rna)-8(l)16( )-24(c)15(o)24(n)-24(t)16(ra)-8(s)8(t)16( )-24(a)15(nd r)-24(e)15(l)16(a)-8(t)16(i)-8(v)24(e)15( )-24(t)-8(u)0(m)-8(o)24(r )-24(s)8(i)16(z)-8(e)15( )-24(t)-8(o)]TJ T* 0.512 Tw [(b)24(a)-8(c)15(kgr)-24(o)24(u)0(n)-24(d)24( )24(m)-8(e)15(di)-8(um)16( i)-8(s)32( p)24(r)-24(e)15(s)8(e)15(n)-24(t)16(.)12( T)16(h)-24(e)15(s)8(e)15( f)23(i)-8(ndi)16(n)-24(g)0(s)32( n)-24(o)24(t)-8( )-24(o)24(n)0(l)-8(y)48( )-24(pr)-24(o)24(v)24(i)-8(de)15( )-24(a)-8( )-24(c)15(o)24(m)-8(p)24(r)-24(e)15(h)-24(e)39(n)-24(s)8(i)-8(v)24(e)]TJ T* 0.004 Tc 0.341 Tw [(unde)19(r)-20(s)12(t)20(a)19(n)-20(d)28(i)20(n)-20(g)28( )24(o)28(f)27( )24(e)19(xpec)19(t)-4(e)19(d)4( )24(me)19(as)12(u)28(r)-20(e)19(m)-4(e)19(n)4(t )47(pe)19(r)-20(f)27(o)28(r)-20(m)20(a)19(n)-20(c)19(e)19( as)12(s)12(o)28(c)19(iate)19(d w)36(i)-4(t)20(h)4( t)20(h)-20(e)19( )24(tw)36(o)28( t)-28(y)52(pes)12( of)]TJ T* 0 Tc 0.012 Tw [(pa)15(r)-24(a)15(m)-8(e)15(t)-8(e)15(r s)8(p)24(a)-8(c)15(e)15(s)8( e)15(xpl)-8(o)24(r)-24(e)15(d)0(,)-12( \()]TJ /F7 1 Tf 11.3571 -0.052 TD 0.008 Tc [(i.)20(e)23(.)]TJ /F5 1 Tf 1.2143 0.052 TD 0.028 Tw [( )48(me)23(as)16(u)32(r)-16(e)23(m)0(e)47(n)-16(t)24( )24(a)23(n)8(d)8( )48(ta)23(r)-16(g)8(e)23(t)24( d)8(o)32(ma)23(i)24(n)-16(s)16(\))8(,)20( b)32(u)8(t )24(als)16(o)32( p)32(r)-16(o)32(v)32(i)0(d)8(e)23( a g)32(u)8(id)8(e)23( )24(to)]TJ -12.5714 -1.1429 TD 0.242 Tw [(id)8(e)23(n)8(tif)8(y)56(i)0(n)-16(g)32( t)24(h)-16(e)23( o)32(p)8(t)24(i)0(c)23(a)0(l)24( me)23(as)16(u)32(r)-16(e)23(m)0(e)47(n)8(t )-24(s)16(t)24(r)8(ate)23(g)32(i)0(e)23(s)16( r)-16(e)23(q)8(u)8(i)24(r)-16(e)23(d)8( to)32( )-24(o)32(b)32(tain)8( )-24(o)32(p)8(ti)24(ma)23(l )-24(s)16(e)47(n)-16(s)16(it)24(iv)32(ity)56( )-24(an)-16(d)]TJ T* 0.123 Tw [(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( to)32( )24(i)24(n)-16(c)23(l)0(u)8(d)8(e)23(d)8( o)32(b)32(j)24(ec)23(ts)16(. I)31(n)8( t)24(h)-16(e)47( f)31(o)32(llo)8(w)40(i)0(n)-16(g)8(,)20( )-24(w)40(e)23( )-24(e)23(x)8(te)23(n)-16(d)8( th)-16(e)23(s)16(e)23( )-24(o)32(b)32(s)16(e)23(r)-16(v)32(atio)32(n)-16(s)16( a)23(n)-16(d)32( )-24(d)8(i)0(s)16(c)23(u)8(s)16(s)]TJ T* 0.009 Tc 0.003 Tw [(c)24(o)33(mp)9(le)24(me)24(n)-15(t)25(a)24(r)-15(y)57( s)17(t)1(r)-15(a)24(te)24(g)9(i)1(e)24(s)17( t)25(h)9(at)25( c)24(a)24(n)9( o)33(p)9(tim)25(ize)24( )24(ac)48(h)-15(i)1(e)24(v)33(ab)33(le)24( s)17(e)24(n)-15(s)17(itiv)33(ity)57( a)24(n)-15(d)33( )24(r)-15(e)24(s)17(o)33(lu)9(tio)33(n)9(.)]TJ /F3 1 Tf 0 -1.801 TD 0 Tc (4.)Tj /F11 1 Tf 0.7619 -0.02 TD 0 Tw ( )Tj /F3 1 Tf 1.0238 0.02 TD -0.008 Tc [(Di)-16(sc)-16(u)24(ssi)-16(o)-8(n)]TJ /F5 1 Tf -1.7857 -1.6752 TD 0.008 Tc 0.171 Tw [(I)8(n)8( t)24(h)8(is)16( )24(r)-16(e)23(p)8(o)32(r)8(t)0( w)40(e)23( )24(h)-16(a)0(v)32(e)23( s)-8(y)56(s)16(t)0(e)23(matic)23(al)24(ly)56( e)23(x)8(p)8(l)0(o)32(r)-16(e)23(d)8( t)24(h)-16(e)23( p)32(a)23(r)-16(a)23(me)23(te)47(r)-16( d)8(o)32(m)24(a)0(i)24(n)-16(s)40( as)16(s)16(o)32(c)23(iate)23(d)8( )-23(w)40(i)0(t)24(h)8( )-23(t)24(h)-16(e)]TJ 0 -1.1429 TD -0.016 Tc 0.218 Tw [(t)-24(a)-1(r)-40(g)-16(et p)8(r)-40(o)8(p)-16(er)-40(ti)-24(es)-8( an)-16(d)-16( )23(m)-24(e)-1(a)-24(s)-8(u)8(r)-40(em)-24(e)23(n)-40(t co)8(n)-40(d)-16(it)-24(i)-24(o)8(n)-40(s)16(,)-28( f)7(o)8(r)-40( )23(th)-40(e p)-16(u)8(r)-16(p)-16(o)8(s)-8(e)-1( o)-16(f)7( g)-16(a)-24(in)-40(in)-16(g)-16( in)-40(s)-8(i)-24(g)8(h)-16(t)-24( in)-40(t)-24(o)8( th)-40(e)]TJ 0 -1.119 TD 0.008 Tc 0.123 Tw [(r)-16(e)23(l)24(atio)56(n)-16(s)40(h)-16(i)0(p)8(s)40( b)32(e)23(tw)16(e)23(e)23(n)-16( t)24(h)-16(e)23(s)16(e)23( d)8(o)32(mai)24(n)-16(s)40( a)23(n)8(d)8( )24(t)24(h)-16(e)23(i)24(r)8( p)8(o)32(s)16(s)16(i)0(b)32(l)0(e)23( in)-16(f)31(l)0(u)8(e)23(n)-16(c)23(e)23( o)56(n)-16( )24(t)24(h)-16(e)23( d)8(e)23(s)16(i)0(g)32(n)8( o)32(f)31( )-24(p)8(r)-16(ac)23(t)24(i)0(c)23(a)0(l)]TJ 0 -1.1429 TD 0.075 Tw [(im)24(ag)8(i)24(n)-16(g)32( )23(s)16(y)56(s)16(t)0(e)23(m)0(s)16(.)-4( Tw)40(o)32( c)23(r)-16(i)24(tic)23(al)24( p)32(a)23(r)-16(a)23(me)23(te)47(r)-16(s)16( t)24(h)8(at)24( s)40(h)-16(o)32(u)8(ld)8( b)32(e)23( k)8(e)23(p)8(t)24( i)24(n)8( m)24(i)24(n)-16(d)32( w)40(h)-16(e)23(n)8( d)8(e)23(s)16(i)0(g)32(n)8(i)24(n)-16(g)32( s)16(u)8(c)23(h)]TJ T* 0.171 Tw [(s)-8(y)56(s)16(t)0(e)23(m)0(s)16( ar)-16(e)23( e)23(x)8(p)8(e)23(c)23(t)0(e)23(d)8( l)24(i)0(m)24(its)40( o)32(n)8( s)16(e)23(n)-16(s)16(i)24(tiv)32(ity)56( )-23(a)23(n)-16(d)8( r)-16(e)23(s)16(o)32(lu)8(tio)56(n)-16(.)20( )-23( )-23(W)47(i)0(t)24(h)-16(o)32(u)8(t a)23( )-23(d)8(o)32(u)8(b)32(t, )-23(a)23(n)8( imp)8(o)56(r)-16(t)24(a)23(n)-16(t)]TJ T* 0.028 Tw [(f)31(a)0(c)23(t)0(o)32(r)-16( i)24(n)-16(f)31(l)0(u)8(e)23(n)-16(c)23(i)24(n)8(g)8( )24(t)24(h)-16(e)23(s)16(e)23( li)24(mi)24(ts)16( w)40(ill)24( b)32(e)23( t)24(h)-16(e)23( v)32(i)0(e)23(w)40( an)-16(g)32(l)0(e)23( o)32(f)31( me)23(as)16(u)8(r)-16(e)23(m)0(e)47(n)-16(t)24(.)20( I)31(n)8( )24(t)24(h)-16(e)23( c)23(a)0(s)16(e)23( o)32(f)31( imag)32(i)24(n)-16(g)]TJ T* 0 Tc 0.107 Tw [(s)8(t)-8(udi)-8(e)15(s)8( o)24(n)0( t)16(h)-24(e)15( b)48(r)-24(e)15(a)-8(s)8(t)16( s)8(e)15(v)24(e)15(r)-24(a)-8(l)-8( o)24(p)0(t)-8(i)-8(o)48(n)-24(s)8( )24(a)15(r)-24(e)15( a)-8(v)24(a)-8(i)16(l)-8(a)-8(b)24(l)-8(e)15(,)12( s)8(o)24(m)-8(e)15( o)24(f)23( )-24(w)32(h)-24(i)-8(c)15(h )24(ha)-8(v)24(e)15( b)24(e)-8(e)15(n)-24( )-24(a)15(d)0(o)24(p)0(t)-8(e)15(d )-24([1-5])23(,)]TJ T* 0.008 Tc 0.171 Tw [(b)32(u)8(t w)40(ith)-16(o)32(u)8(t)24( )24(r)-16(i)0(g)8(o)56(r)-16(o)32(u)8(s)16( p)32(r)-16(o)32(o)8(f)31( th)8(at)24( t)24(h)-16(e)23(s)16(e)23( a)23(r)-16(e)47( b)32(e)23(s)16(t)0( s)16(u)8(ite)23(d)8( f)31(o)32(r)-16( )24(ac)23(h)8(i)0(e)23(v)32(in)-16(g)32( o)32(p)8(ti)24(mal)24( s)16(e)47(n)-16(s)16(it)24(iv)32(ity)56( )-23(an)-16(d)]TJ T* [(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8(.)]TJ 3.5714 -1.1429 TD 0.123 Tw [(O)16(n)-16(e)23( )-24(d)8(e)23(s)16(i)0(g)32(n)8( )-24(i)24(n)8( )-24(p)32(a)23(r)-16(t)24(ic)23(u)8(l)0(a)23(r)8( t)24(h)-16(a)23(t)0( h)8(a)0(s)16( )-24(b)32(e)23(e)23(n)-16( imp)32(le)23(me)47(n)-16(t)0(e)23(d)8( is)16( a r)8(a)0(s)16(t)0(e)23(r)8( )-24(s)16(c)23(a)23(n)8( )-48(w)40(i)0(t)24(h)-16( )-24(a )-48(s)40(i)24(n)-16(g)8(le)]TJ -3.5714 -1.2381 TD 0.29 Tw [(d)8(e)23(te)23(c)23(t)0(o)32(r)-16( p)8(o)32(s)16(itio)32(n)-16(e)23(d)8( )24(1)8(8)8(0)]TJ /F12 1 Tf 9.9048 -0.0477 TD 0 Tc 0 Tw (\260)Tj /F5 1 Tf 0.381 0.0477 TD 0.008 Tc 0.313 Tw [( o)32(p)8(p)8(o)32(s)16(ite)23( t)24(h)-16(e)23( s)16(o)32(u)8(r)-16(c)23(e)23(,)-4( w)40(i)0(t)24(h)8( t)24(h)-16(e)47( b)32(r)-16(e)23(a)0(s)16(t)24( s)16(u)8(b)32(j)24(ec)23(te)23(d)8( to)32( mi)24(ld)8( )23(p)8(l)0(a)23(n)8(a)23(r)]TJ -10.2857 -1.119 TD 0.075 Tw [(c)23(o)32(mp)8(r)-16(e)23(s)16(s)16(i)0(o)32(n)-16( )23([)8(1)8(])31(.)20( )23( W)47(h)-16(i)24(l)0(e)23( c)23(o)32(mp)32(r)-16(e)23(s)16(s)16(i)0(o)32(n)-16( o)32(f)31( th)-16(e)47( b)32(r)-16(e)23(a)0(s)16(t)24( w)40(ill )23(im)24(p)32(r)-16(o)32(v)32(e)23( s)16(i)0(g)8(n)-16(a)23(l)0( )23(le)23(v)32(e)23(ls)16(, t)24(h)-16(is)40( w)40(ill b)32(e)23( a)23(t)]TJ 0 -1.1429 TD 0 Tc 0.179 Tw [(t)16(h)-24(e)15( )24(e)15(xpe)15(n)-24(s)8(e)15( )24(o)24(f)23( )24(a)-8( )48(r)-24(e)15(s)8(t)16(r)-24(i)-8(c)15(t)-8(e)15(d)24( )24(v)24(i)-8(e)15(w)32(.)-12( )24( )24(R)24(e)15(s)8(u)0(l)-8(t)-8(s)8( i)16(n)0( F)8(i)-8(gu)24(r)-24(e)15( )24(9 s)32(h)-24(o)24(w)32( t)-8(h)-24(a)15(t)16( de)15(pe)15(ndi)16(n)-24(g)24( o)24(n)0( t)16(h)-24(e)39( o)24(p)0(t)-8(i)-8(c)15(a)-8(l)]TJ T* 0.06 Tw [(pr)-24(o)24(p)0(e)15(r)0(t)-8(i)-8(e)15(s)8( )24(o)24(f)23( )24(t)-8(h)-24(e)39( )24(b)24(a)-8(c)15(kgr)-24(o)24(u)24(n)-24(d )48(t)-8(i)-8(s)8(s)8(u)0(e)15(s)8( )24(a)15(nd )48(t)16(h)-24(e)15(i)16(r )24(di)-8(s)8(t)16(ri)-8(b)24(u)0(t)-8(i)-8(o)48(n)-24( )24(i)16(n)-24( re)15(l)16(a)-8(t)16(i)-8(o)24(n)0( t)-8(o)24( a)15(n)0( R)24(O)8(I,)12( s)8(e)15(n)-24(s)8(i)16(t)-8(i)-8(v)24(i)-8(t)-8(y)48( t)-8(o)]TJ 0 -1.2381 TD -0.015 Tc 0.241 Tw [(a)-23( cen)-15(tr)-39(al)-23(l)-23(y)33( l)-23(o)9(ca)-23(t)-23(e)0(d)-15( s)-7(t)1(r)-39(u)-15(ct)-23(u)9(r)-39(e can)-15( v)9(a)0(r)-39(y)33( s)-7(e)-23(v)-15(e)0(r)-39(a)-23(l\226)-15(f)8(o)9(l)-23(d)-15( o)-15(v)9(er)-39( an)-15( an)-15(g)-15(l)-23(e o)9(f)8( 2)-15(0)]TJ /F12 1 Tf 30.0476 -0.0477 TD 0 Tc 0 Tw (\260)Tj /F5 1 Tf 0.4048 0.0477 TD 0.008 Tc 0.218 Tw [(.)20( )24( S)16(i)24(n)-16(c)23(e)23( d)8(e)23(ta)23(ile)23(d)]TJ -30.4524 -1.119 TD 0 Tc 0.226 Tw [(kn)-24(o)24(w)32(l)-8(e)15(dge)15( of)23( un)-24(de)39(r)-24(l)-8(y)48(i)-8(n)-24(g)24( s)8(t)16(r)-24(u)0(c)15(t)-8(u)24(r)0(a)-8(l)16( h)-24(e)15(t)-8(e)39(r)-24(o)24(ge)15(n)-24(e)15(i)-8(t)-8(y)48( )-24(of)23( )-24(t)-8(h)-24(e)15( )-24(b)48(r)-24(e)15(a)-8(s)8(t)16( )-24(i)-8(s)8( unk)24(n)-24(o)24(w)32(n)-24( )]TJ /F7 1 Tf 32.1905 -0.052 TD -0.024 Tc 0.274 Tw [(a p)-24(r)-16(i)-32(o)-24(r)-16(i)]TJ /F5 1 Tf 3.3095 0.052 TD -0.014 Tc 0.24 Tw [(, th)-38(e)]TJ -35.5 -1.1429 TD -0.015 Tc 0.289 Tw [(in)-39(f)8(l)-23(u)-15(e)0(n)-39(ce o)9(f)8( s)-7(u)-15(ch)-39( s)-7(t)1(r)-39(u)-15(ct)-23(u)9(r)-39(es)-7( o)33(n)-39( s)-7(e)24(n)-39(s)-7(i)-23(t)1(i)-23(v)9(i)-23(t)-23(y)33( ca)-23(n)-39( b)9(e)0( ex)-15(p)-15(ect)-23(ed)-15( t)-23(o)9( v)9(a)-23(r)-39(y)33( s)-7(i)-23(g)-15(n)-15(i)-23(f)8(i)-23(can)-39(t)-23(l)-23(y)33(.)-27( A)17(t)-23( )24(a)]TJ 0 -1.119 TD 0.004 Tc 0.127 Tw [(mi)20(nimu)28(m)20(,)-8( )24(t)20(h)-20(is)36( o)28(b)28(s)-12(e)19(r)-20(v)28(atio)28(n s)12(ugge)19(s)12(t)-4(s)12( )24(t)20(h)-20(a)19(t)-4( )24(t)20(h)-20(e)19( p)28(r)-20(e)19(s)12(e)19(n)-20(c)19(e)19( o)28(f)27( h)-20(e)19(te)19(r)-20(o)28(ge)19(n)-20(e)19(o)28(u)4(s)12( )-24(b)28(a)-4(c)19(kgr)-20(o)28(u)28(n)-20(ds)12( i)20(n)4( )-24(t)20(h)-20(e)]TJ 0 -1.1429 TD 0.008 Tc 0.028 Tw [(b)32(r)-16(e)23(a)0(s)16(t)0( w)40(ill)24( s)16(e)23(v)32(e)23(r)-16(e)23(l)-24(y)56( lim)24(it)24( e)23(f)8(f)8(o)32(r)-16(t)0(s)16( )24(to)32( o)32(b)32(tain)8( )24(r)-16(e)23(p)32(r)-16(o)32(d)8(u)8(c)23(ib)32(le)23( r)-16(e)23(s)16(u)8(l)24(t)0(s)16( f)31(r)-16(o)32(m)24( )-24(me)23(as)16(u)32(r)-16(e)23(m)0(e)47(n)-16(ts)40( )-24(e)23(m)0(p)32(l)0(o)8(y)56(in)-16(g)]TJ T* 0.075 Tw [(r)-16(e)23(s)16(t)24(r)-16(i)0(c)23(t)0(e)23(d)32( v)32(i)0(e)23(w)16(s)16(.)-4( T)24(h)8(is)16( w)40(o)32(u)8(l)0(d)8( b)32(e)23( e)23(s)16(p)8(e)0(c)23(ially)56( tr)8(u)8(e)23( s)40(h)-16(o)32(u)8(ld)8( s)16(e)47(r)-16(i)0(a)23(l)0( )-24(m)24(e)23(as)16(u)32(r)-16(e)23(m)0(e)47(n)-16(ts)40( )-24(b)32(e)23( )-24(p)8(e)23(r)-16(f)31(o)32(r)-16(me)23(d)8(,)20( )-24(i)24(n)]TJ T* 0 Tc 0.131 Tw [(w)32(h)-24(i)-8(c)15(h c)15(a)-8(s)8(e)15( t)16(h)-24(e)15( )24(pl)-8(a)-8(s)32(t)-8(i)-8(c)15(i)-8(t)-8(y)48( o)24(f)23( t)-8(h)-24(e)15( b)24(r)-24(e)15(a)-8(s)8(t)16( w)32(o)24(ul)-8(d s)8(u)0(r)-24(e)15(l)-8(y)48( unde)15(rm)-8(i)16(n)-24(e)39( e)15(ffo)24(r)-24(t)-8(s)8( )24(t)-8(o)24( )24(r)-24(e)15(p)24(r)-24(o)24(duc)15(e)15( pr)-24(e)15(c)15(i)-8(s)8(e)]TJ T* 0.004 Tc 0.175 Tw [(po)28(s)12(itio)28(n)-20(i)20(ng o)28(f)27( t)20(h)-20(e)19( t)20(i)-4(s)12(s)12(u)4(e)19(.)-8( )24( B)28(e)19(c)19(a)-4(us)12(e)19( )-23(b)28(a)-4(c)19(kgr)-20(o)28(und )24(h)-20(e)19(te)43(r)-20(o)28(ge)19(n)-20(e)19(ity)52( c)19(a)-4(n s)36(h)-20(if)27(t t)20(h)-20(e)19( lo)28(c)19(atio)28(n)-20( )-23(w)59(h)-20(e)19(r)-20(e)]TJ T* 0.008 Tc 0.147 Tw [(o)32(p)8(tima)23(l )24(s)16(e)47(n)-16(s)16(it)24(iv)32(ity)56( )24(is)16( ac)47(h)-16(i)0(e)23(v)32(e)23(d)8(, o)32(u)8(r)8( )24(r)-16(e)23(s)16(u)8(lts)16( s)16(u)32(g)8(g)8(e)23(s)16(t)0( t)24(h)8(a)23(t)0( )24(imp)32(r)-16(o)32(v)32(e)23(d)8( r)-16(e)23(p)32(r)-16(o)32(d)8(u)8(c)23(ib)32(ility)56( s)16(h)-16(o)32(u)8(ld)32( b)32(e)]TJ T* 0.075 Tw [(ac)23(h)8(i)0(e)23(v)32(ab)32(le)23( u)8(s)16(in)-16(g)32( me)23(as)16(u)32(r)-16(e)47(m)0(e)23(n)8(t s)16(c)47(h)-16(e)23(me)23(s)16( t)24(h)8(at)24( e)23(m)0(p)32(l)0(o)8(y)56( b)32(r)-16(o)32(a)0(d)8(e)23(r)-16( v)32(i)0(e)23(w)40(s)16(.)-4( T)24(h)-16(e)23( )-24(d)32(i)0(f)31(f)31(i)0(c)23(u)8(lt)-24(y)56( )-24(w)40(ith)-16( t)24(h)-16(is)]TJ ET endstream endobj 100 0 obj << /ProcSet [/PDF /Text ] /Font << /F3 4 0 R /F5 5 0 R /F7 6 0 R /F11 13 0 R /F12 26 0 R >> /ExtGState << /GS1 8 0 R >> >> endobj 102 0 obj << /Length 21182 >> stream 1 1 1 rg /GS1 gs 21 -66 612 792 re f BT /F5 1 Tf 10.08 0 0 10.08 117.48 711.6 Tm 0 0 0 rg 0.008 Tc 0.123 Tw [(ap)8(p)32(r)-16(o)32(a)0(c)23(h)8( is)40( t)24(h)8(at)24( i)24(t)0( )24(may)56( li)24(mit)24( t)24(h)-16(e)47( ab)32(il)24(ity)56( to)32( u)8(s)16(e)23( p)8(l)0(a)23(n)8(a)23(r)8( c)23(o)32(mp)8(r)-16(e)23(s)16(s)16(i)0(o)32(n)8( s)16(c)23(h)-16(e)23(me)23(s)16(.)20( )-24( )-24(A)16(s)16( i)24(n)-16(d)32(i)0(c)23(ate)23(d)8(,)]TJ 0 -1.1429 TD 0.052 Tw [(w)40(h)-16(ile)23( i)24(t)0( c)23(l)0(e)23(a)23(r)8( )24(t)24(h)-16(a)23(t)0( c)23(o)32(mp)32(r)-16(e)23(s)16(s)16(i)0(o)32(n)-16( o)32(f)31( t)24(h)-16(e)23( t)24(i)0(s)16(s)16(u)8(e)23( w)40(ill )24(imp)32(r)-16(o)32(v)32(e)23( s)16(i)0(g)8(n)8(a)23(l )24(le)23(v)32(e)23(ls)16(, it)24( is)16( w)40(o)32(r)-16(t)24(h)8( e)23(x)8(a)23(m)0(i)24(n)8(i)24(n)-16(g)]TJ T* 0.385 Tw [(w)40(h)-16(e)23(t)0(h)-16(e)47(r)-16( )48(t)24(h)-16(is)40( )24(is)40( )24(ac)23(c)23(o)32(mp)8(a)23(n)-16(ie)23(d)8( b)32(y)56( e)23(x)8(p)8(e)0(c)23(t)0(e)23(d)8( imp)32(r)-16(o)32(v)32(e)23(me)23(n)-16(t)0(s)16( )24(i)24(n)-16( s)16(e)23(n)8(s)16(it)24(iv)32(ity)56( an)-16(d)32( )24(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8(.)]TJ T* 0.075 Tw [(A)16(l)0(t)24(h)-16(o)32(u)8(g)32(h)-16( p)32(l)0(a)23(n)8(a)23(r)8( c)23(o)32(mp)8(r)-16(e)23(s)16(s)16(i)0(o)32(n)8( g)8(e)23(o)32(m)0(e)23(t)0(r)8(i)0(e)23(s)16( w)40(e)23(r)-16(e)23( n)-16(o)32(t)24( s)16(p)8(e)23(c)23(i)0(f)31(i)0(c)23(ally)56( in)-16(v)32(e)23(s)16(tig)8(ate)23(d)8( )23(i)24(n)8( t)24(h)8(is)16( s)16(t)0(u)8(d)8(y)56(, )-24(w)40(e)]TJ T* 0.171 Tw [(b)32(e)23(liev)32(e)23( )24(th)-16(a)23(t)0( )24(c)23(o)32(mp)8(a)23(r)8(is)16(o)32(n)8( )24(o)32(f)31( )24(r)-16(e)23(s)16(u)8(lts)16( f)55(r)-16(o)32(m)0( t)24(h)-16(e)47( d)8(i)0(f)31(f)31(e)23(r)-16(e)23(n)-16(t)24( b)32(r)-16(e)23(a)0(s)16(t)24( s)16(ize)23(s)40( c)23(a)23(n)-16( )24(n)-16(e)23(v)32(e)23(r)-16(t)24(h)-16(e)23(le)23(s)16(s)16( p)32(r)-16(o)32(v)32(i)0(d)8(e)]TJ 0 -1.1191 TD -0.015 Tc 0.027 Tw [(in)-39(s)-7(i)-23(g)9(h)-15(t)-23( )24(in)-39(t)-23(o)9( th)-39(e)24( ex)-15(p)-15(ect)-23(ed)-15( in)-39(f)8(l)-23(u)-15(e)0(n)-39(ce o)9(f)8( s)-7(u)-15(ch)-39( g)-15(e)0(o)9(m)-23(et)-23(r)-15(i)-23(es)-7( o)9(n)-15( th)-39(es)-7(e p)-15(a)0(r)-15(a)0(m)-23(e)0(t)-23(e)0(r)-39(s)-7(.)]TJ 3.5714 -1.1428 TD 0.008 Tc 0.028 Tw [(B)32(e)0(c)23(a)0(u)8(s)16(e)23( th)-16(e)23( )24(i)24(n)8(te)23(r)8(n)8(a)0(l)24( f)31(e)23(atu)32(r)-16(e)23(s)16( o)32(f)31( th)-16(e)23( d)32(i)0(f)31(f)31(e)23(r)-16(e)23(n)-16(t)0( b)56(r)-16(e)23(a)0(s)16(t)0( )24(mo)32(d)8(e)23(ls)16( s)16(t)0(u)8(d)32(ie)23(d)8( a)23(r)-16(e)47( id)8(e)47(n)-16(t)24(i)0(c)23(a)0(l)24(,)-4( )24(to)32( a)]TJ -3.5714 -1.1429 TD 0.242 Tw [(f)31(i)0(r)-16(s)16(t )24(ap)8(p)32(r)-16(o)32(x)8(i)24(m)0(a)23(tio)56(n)-16( c)23(o)32(mp)8(a)23(r)8(is)16(o)32(n)-16( o)32(f)31( )-24(r)-16(e)23(s)16(u)8(l)24(t)0(s)16( )-24(f)31(o)32(r)-16( )-24(d)32(i)0(f)31(f)8(e)23(r)-16(e)23(n)8(t mo)32(d)8(e)23(l )-24(d)8(i)24(ame)23(te)47(r)-16(s)16( is)16( )-24(e)23(q)8(u)8(i)0(v)32(ale)47(n)8(t)0( to)]TJ T* -0.008 Tc 0.068 Tw [(i)-16(m)-16(p)-8(o)16(s)0(i)8(n)-32(g)-8( )48(a)7( )24(r)-32(a)-16(d)16(i)-16(a)7(l)-16( c)7(o)16(m)-16(p)16(r)-32(e)7(ssi)-16(o)16(n)-32( o)40(n)-32( )24(t)8(h)-32(e)7( t)8(i)-16(ssu)-8(e)7(.)-20( )24(T)-16(a)-16(b)16(l)-16(e)7( 4)16( l)8(i)-16(st)-16(s )24(r)-32(e)7(su)-8(l)8(t)-16(s d)-8(e)31(r)-32(i)-16(v)16(e)7(d)-8( f)15(r)-32(o)16(m)-16( F)24(i)-16(g)-8(u)16(r)-32(e)7(s 5)16( \()-8(a)-16(\))15(\226)]TJ T* 0 Tc 0.298 Tw [(\(b)24(\) a)15(n)-24(d )24(6 \()23(a)-8(\)\226\(b)24(\),)12( w)32(h)-24(e)15(r)-24(e)39( t)16(h)-24(e)15( e)15(xpe)15(c)15(t)-8(e)15(d)0( i)16(n)-24(f)23(l)-8(ue)39(n)-24(c)15(e)15( o)24(f)23( a)-8( )-23(ra)-8(d)24(i)-8(a)15(l)-8( )-23(c)15(o)24(m)-8(p)24(r)-24(e)15(s)8(s)8(i)-8(o)24(n)-24( m)-8(a)15(n)-24(e)15(uv)24(e)15(r)-24( )-23(o)48(n)]TJ T* 0.008 Tc 0.194 Tw [(s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56( an)-16(d)32( e)23(d)8(g)8(e)23( )23(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( o)32(f)31( th)-16(e)23( tu)8(mo)56(r)-16( is)16( )-24(e)23(x)8(a)23(m)0(i)24(n)-16(e)23(d)32( )-24(as)16(s)16(u)8(m)24(i)24(n)-16(g)32( )-24(d)32(i)0(f)31(f)8(e)23(r)-16(e)23(n)8(t )-24(c)23(o)32(mp)32(r)-16(e)23(s)16(s)16(i)0(o)32(n)]TJ T* 0 Tc 0.202 Tw [(r)-24(e)15(s)8(p)0(o)24(n)-24(s)8(e)15(s)8( )23(o)24(f)23( )23(a)-8(n)0( )23(i)16(n)-24(c)15(l)-8(u)24(d)0(e)15(d)0( t)-8(u)24(m)-8(o)24(r.)12( F)8(o)24(r s)8(i)16(m)-8(p)0(l)16(i)-8(c)15(i)-8(t)-8(y)48(,)-12( e)15(xpe)15(c)15(t)-8(e)15(d)0( o)24(u)0(t)-8(\226)0(o)24(f\226pl)-8(a)15(n)-24(e)15( e)15(f)0(f)23(e)-8(c)15(t)-8(s)8( o)24(f)23( t)-8(i)-8(s)8(s)8(u)0(e)15(\226)]TJ T* -0.015 Tc 0.17 Tw [(t)-23(u)-15(m)-23(o)9(r)-15( co)9(m)-23(p)9(r)-39(e)0(s)-7(s)-7(i)-23(o)9(n)-39( )24(ar)-39(e i)-23(g)9(n)-39(o)33(r)-39(e)0(d)-15(.)-3( C)-15(o)9(n)-39(s)-7(i)-23(d)-15(e)24(r)-39(ed)-15( i)-23(s)-7( )-24(a )-24(lar)-39(g)-15(e )-24(b)33(r)-39(ea)-23(s)-7(t)-23( )-24(\()8(1)-15(6)9( )-24(cm)-23(\))-15( )-24(co)9(n)-15(t)-23(ain)-39(i)1(n)-39(g)9( a)-23( t)-23(u)-15(m)-23(o)33(r)]TJ T* 0.008 Tc 0.028 Tw [(w)40(h)-16(o)32(s)16(e)23( s)16(ize)23( \()8(1)8(.)-4(6)32( c)23(m)0(\))8( )24(is)16( 1)32(%)8( o)32(f)31( t)24(h)-16(e)23( to)32(ta)23(l c)47(r)-16(o)32(s)16(s)16(\226)8(s)16(e)23(c)23(tio)32(n)-16(al a)23(r)-16(e)23(a)23( r)-16(a)0(t)24(i)0(o)32(.)20( )-24( T)24(h)-16(e)23(s)16(e)23( )-24(r)-16(e)23(s)16(u)8(l)24(t)0(s)16( )-24(s)40(h)-16(o)32(w)40( )-24(th)8(at)24( )-24(u)8(s)16(e)]TJ T* 0.075 Tw [(o)8(f)31( c)23(o)32(mp)8(r)-16(e)23(s)16(s)16(i)0(o)32(n)-16( te)23(c)47(h)8(n)-16(i)0(q)8(u)8(e)23(s)16( )23(is)16( )23(alw)40(ay)32(s)16( ac)23(c)23(o)32(mp)8(an)8(ie)23(d)8( a)23( lo)32(s)16(s)16( o)32(f)31( r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( d)8(u)8(e)23( to)32( r)-16(e)23(d)8(u)8(c)23(e)23(d)8( )-24(b)32(r)-16(e)23(a)0(s)16(t)]TJ T* 0.009 Tc 0.027 Tw [(s)17(ize)24(, )24(w)41(h)9(ile)24( )48(its)41( )24(e)24(f)9(f)32(e)1(c)24(t)1( )24(o)33(n)-15( )24(s)17(e)48(n)-15(s)17(it)25(iv)33(ity)57( d)9(e)24(p)9(e)24(n)-15(d)9(s)17( o)33(n)9( t)25(h)-15(e)24( )24(d)9(e)24(g)9(r)-15(e)24(e)24( o)33(f)32( c)24(o)33(mp)9(r)-15(e)24(s)17(s)17(i)1(b)33(ility)57( o)9(f)32( th)-15(e)24( )24(tu)9(mo)57(r)-15( w)41(i)1(t)25(h)]TJ T* 0.008 Tc 0.052 Tw [(r)-16(e)23(s)16(p)8(e)23(c)23(t)0( to)32( t)24(h)-16(e)23( s)16(u)32(r)8(r)-16(o)32(u)32(n)-16(d)32(i)24(n)-16(g)32( t)24(i)0(s)16(s)16(u)8(e)23(.)-4( )24( I)31(n)-16( t)24(h)-16(e)23( )-23(c)23(a)0(s)16(e)23( )-23(w)40(h)-16(e)47(r)-16(e)23( )-23(t)24(h)-16(e)47( )-23(tu)32(mo)32(r)8( h)-16(a)0(s)40( )-23(s)16(i)24(mil)24(a)23(r)8( )-23(c)23(o)32(mp)8(r)-16(e)23(s)16(s)16(i)0(b)32(ili)24(ty)56( )-23(to)]TJ 0 -1.119 TD 0 Tc 0.06 Tw [(t)16(h)-24(e)15( s)8(u)24(rr)-24(o)24(undi)16(n)-24(g)24( )24(m)-8(e)15(di)-8(a)15(,)-12( )24(ra)-8(d)24(i)-8(a)-8(l)16( c)15(o)24(m)-8(p)24(r)-24(e)15(s)8(s)8(i)-8(o)24(n)-24( o)24(f)23( t)16(h)-24(e)15( t)-8(i)-8(s)8(s)8(u)0(e)15( )24(t)-8(o)24( 10 c)39(m)-8( d)24(i)-8(a)15(m)-8(e)15(t)-8(e)15(r)0( c)15(a)-8(us)8(e)15(s)8( a)15( 29)24(% a)15(n)-24(d)]TJ 0 -1.1429 TD 0.005 Tc 0.388 Tw [(35% )48(lo)29(s)13(s)13( )24(of)28( s)13(e)20(n)-19(s)13(itiv)29(ity)53( a)20(n)-19(d)29( e)20(dge)20( )24(r)-19(e)20(s)13(o)29(lutio)29(n,)-7( )24(r)-19(e)20(s)13(p)5(e)20(c)20(tiv)29(e)20(l)-27(y)53(.)-7( T)21(h)-19(e)20(s)13(e)20( v)29(alue)20(s)13( c)20(o)29(mpa)20(r)-19(e)20( to)]TJ T* 0 Tc 0.083 Tw [(c)15(o)24(r)-24(r)-24(e)15(s)8(p)0(o)24(n)-24(di)16(ng de)15(c)15(l)-8(i)16(n)-24(e)15(s)8( o)24(f)23( 16% )23(a)15(n)-24(d)24( 34)24(% f)23(o)24(r)-24( )23(t)16(h)-24(e)15( c)15(a)-8(s)8(e)15( o)24(f)23( pa)-8(rt)-8(i)-8(a)15(l)16( t)-8(u)24(m)-8(o)24(r )-24(c)15(o)24(m)-8(p)0(r)-24(e)15(s)8(s)8(i)-8(o)24(n)0(,)-12( a)15(n)-24(d)24( )-24(t)-8(o)24( a)]TJ T* (25% )Tj /F7 1 Tf 2.1667 -0.052 TD -0.024 Tc [(ga)-24(i)-32(n)]TJ /F5 1 Tf 1.7381 0.052 TD 0.008 Tc 0.099 Tw [( i)24(n)8( s)16(e)23(n)-16(s)40(itiv)32(ity)56( c)23(o)32(u)8(p)8(l)0(e)23(d)8( w)40(ith)-16( )24(a)23( 3)8(1)8(%)31( )]TJ /F7 1 Tf 14.4286 -0.052 TD [(lo)8(s)16(s)]TJ /F5 1 Tf 1.5238 0.052 TD [( o)32(f)31( r)-16(e)23(s)16(o)32(lu)8(tio)32(n)-16( f)31(o)32(r)-16( )24(a)23(n)8( i)24(n)-16(c)23(o)32(mp)32(r)-16(e)23(s)16(s)16(i)0(b)32(l)0(e)23( tu)8(mo)56(r)-16(.)]TJ -19.8571 -1.1429 TD -0.008 Tc 0.306 Tw [(T)8(h)-32(e)7(s)0(e)7( r)-32(e)7(su)-8(l)8(t)-16(s s)24(h)-32(o)16(w)24( t)-16(h)-8(a)-16(t)8( t)8(i)-16(ssu)-8(e)7( c)7(o)16(m)-16(p)-8(r)-32(e)7(ssi)-16(o)16(n)]TJ /F7 1 Tf 18.5 -0.052 TD 0 Tc 0.274 Tw [( pe)-8(r)8( )-24(s)32(e)-8( )]TJ /F5 1 Tf 3.7619 0.052 TD -0.015 Tc 0.336 Tw [(d)-15(o)9(es)-7( )47(n)-39(o)9(t)-23( )23(g)-15(u)9(ar)-39(an)-15(t)-23(ee im)-23(p)9(r)-39(o)9(v)9(e)0(m)-23(e)0(n)-39(t)-23( in)]TJ -22.2619 -1.1429 TD 0.008 Tc 0.004 Tw [(s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56( an)-16(d)32( )24(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8(,)-4( )24(a)23(n)-16(d)32( )24(n)-16(o)32(t i)24(n)-16(f)55(r)-16(e)23(q)8(u)8(e)23(n)8(tly)56( c)23(a)0(n)8( m)24(a)0(k)8(e)23( )24(ma)23(tte)47(r)-16(s)16( w)40(o)32(r)-16(s)16(e)23(.)]TJ 3.5714 -19.1667 TD 0.028 Tw [(A)16(s)16( )-24(me)47(n)-16(tio)56(n)-16(e)23(d)8(,)20( )-24(a)23(n)8( )-24(i)24(m)0(p)8(o)32(r)8(t)0(a)23(n)8(t m)24(atte)47(r)8( r)-16(e)23(la)23(te)23(d)8( )-24(to)32( i)24(n)-16(s)16(t)24(r)-16(u)32(me)23(n)8(t)0( d)8(e)23(s)16(i)0(g)32(n)-16( is)16( )-24(t)24(h)-16(e)23( )-47(v)32(i)0(e)23(w)40( )-47(an)-16(g)32(l)0(e)23( )-47(o)32(f)]TJ -3.5714 -1.1429 TD 0.052 Tw [(me)23(as)16(u)32(r)-16(e)23(m)0(e)23(n)8(t.)20( )24( )-23(S)16(e)23(v)32(e)23(r)-16(al )-23(g)32(r)-16(o)32(u)8(p)8(s)40( h)-16(a)0(v)32(e)23( r)-16(e)23(p)8(o)32(r)-16(t)0(e)23(d)8( i)24(n)-16(s)16(t)24(r)-16(u)32(me)47(n)-16(t)24( )-23(d)8(e)23(s)16(i)0(g)32(n)-16(s)16( t)24(h)-16(a)23(t)0( r)-16(e)23(s)16(t)24(r)8(i)0(c)23(t)0( me)23(as)16(u)32(r)-16(e)23(m)0(e)47(n)-16(t)24( )-23(o)32(f)]TJ T* 0.075 Tw [(t)24(h)-16(e)23( e)23(x)8(it)24(i)24(n)-16(g)32( o)32(p)8(tic)23(al)24( s)16(i)0(g)32(n)8(al)24( to)32( t)24(h)-16(e)47( lo)32(c)23(atio)56(n)-16( o)32(p)8(p)8(o)32(s)16(ite)23( t)24(h)-16(e)23( )-24(s)16(o)32(u)8(r)-16(c)23(e)23(.)20( )-24(A)16( )-24(c)47(r)-16(i)24(tic)23(a)23(l)0( is)16(s)16(u)8(e)23( )-24(i)24(n)-16(f)31(l)0(u)8(e)23(n)-16(c)23(i)24(n)8(g)8( t)24(h)-16(e)]TJ T* 0.099 Tw [(p)8(e)23(r)-16(f)31(o)32(r)-16(ma)23(n)-16(c)23(e)23( o)32(f)31( s)16(u)8(c)23(h)-16( s)16(y)56(s)16(t)0(e)23(m)0(s)16( is)16( l)24(i)0(m)24(its)16( o)56(n)-16( )-24(e)23(d)8(g)8(e)23( r)-16(e)23(s)16(o)32(lu)8(tio)56(n)-16( a)23(n)-16(d)8( )-24(s)16(e)47(n)-16(s)16(i)24(tiv)32(ity)56( )-24(to)32( )-24(a )-24(s)16(e)23(le)23(c)23(t)0(e)23(d)8( )-24(R)32(O)16(I)8(.)]TJ T* -0.015 Tc 0.075 Tw [(We h)-39(a)-23(v)9(e)0( o)9(b)9(s)-31(er)-39(v)9(e)0(d)-15( th)-39(a)-23(t)1( e)24(n)-15(h)-39(a)0(n)-39(cem)-23(e)24(n)-39(t o)9(f)8( b)-15(o)9(t)-23(h)-39( can)-15( )-23(b)9(e)0( )-23(a)-23(c)0(h)-15(i)-23(ev)9(ed)-15( )-23(u)-15(p)-15(o)9(n)-39( an)-39( in)-39(c)24(r)-39(ea)-23(s)-7(e)0( )-23(in)-15( )-23(th)-39(e )-23(s)17(i)-23(z)-23(e)0( )-23(o)9(f)]TJ T* 0.008 Tc [(t)24(h)-16(e)23( me)23(d)8(i)24(u)8(m)24(, w)40(h)8(ic)47(h)-16( )23(is)16( e)23(q)8(u)8(i)0(v)32(ale)47(n)-16(t)24( to)32( )23(a)23(n)-16( )23(i)24(n)-16(c)47(r)-16(e)23(a)0(s)16(e)23( i)24(n)8( i)24(t)0(s)16( to)32(ta)23(l )-24(o)32(p)8(tic)47(al)24( )-24(t)24(h)8(ic)23(k)32(n)-16(e)23(s)16(s)16(.)-4( )-24( )-24(W)47(h)8(ile)23( )-24(s)16(u)8(c)47(h)-16( a)23(n)]TJ T* 0.009 Tc 0.003 Tw [(i)25(n)-15(c)24(r)-15(e)24(a)1(s)17(e)24( w)41(ill)25( )24(r)-15(e)24(d)9(u)9(c)24(e)24( o)33(b)33(s)-7(e)24(r)-15(v)33(a)1(b)33(l)1(e)24( s)17(i)1(g)9(n)9(a)1(l)25( le)24(v)33(e)24(ls)17(, t)25(h)-15(e)24( )24(r)-15(e)24(l)25(a)1(t)25(i)1(v)33(e)24(l)-23(y)57( h)-15(i)1(g)33(h)9( )24(i)25(n)-15(te)48(n)-15(s)17(i)25(tie)24(s)17( )-24(o)33(f)32( )-24(lig)33(h)-15(t)25( )-24(t)25(h)9(at)25( )-24(c)24(a)24(n)9( )-24(b)33(e)]TJ 0 -1.119 TD 0 Tc 0.179 Tw [(di)16(r)-24(e)15(c)15(t)-8(e)15(d)0( t)-8(o)24( t)-8(i)-8(s)8(s)8(u)0(e)15( w)32(i)-8(t)16(h)-24(o)24(u)0(t)16( c)15(a)-8(us)8(i)16(n)-24(g)24( d)24(a)-8(m)16(a)-8(ge)15( s)8(ugge)15(s)8(t)-8(s)8( )24(t)16(h)-24(a)15(t)-8( t)16(h)-24(i)-8(s)32( )-23(t)-8(r)0(a)15(d)0(e)15(o)24(ff)23( )-23(c)15(a)-8(n)-24( )-23(b)24(e)15( )-23(m)16(a)-8(de)15( )-23(o)24(v)24(e)15(r)-24( )-23(a)]TJ 0 -1.1429 TD 0.008 Tc 0.218 Tw [(s)16(e)23(le)23(c)23(t)0(e)23(d)8( r)-16(a)23(n)-16(g)8(e)47(,)-4( u)8(p)32( to)32( )24(t)24(h)-16(e)23( l)24(i)0(m)24(i)0(t)24( o)32(f)31( p)8(h)-16(o)32(t)0(o)32(n)8( d)8(e)23(p)8(r)8(i)0(v)32(atio)56(n)-16(.)20( )24( I)8(t)24( is)16( )24(u)8(s)16(e)23(f)31(u)8(l)0( )-24(to)32( )-24(c)23(o)32(n)-16(s)16(id)8(e)23(r)8( )-24(s)16(t)24(r)8(ate)23(g)8(i)0(e)23(s)]TJ T* 0.004 Tw [(w)40(h)-16(e)23(r)-16(e)23(b)8(y)56( th)-16(is)40( c)23(o)32(u)8(l)0(d)8( b)32(e)23( ef)31(f)8(e)23(c)23(tiv)8(e)23(l)-24(y)56( ac)23(co)32(mp)8(lis)40(h)-16(e)23(d)8(.)]TJ 3.5714 -1.1429 TD 0.313 Tw [(O)16(n)-16(e)23( )23(ap)8(p)32(r)-16(o)32(a)0(c)47(h)-16( w)40(o)32(u)8(l)0(d)8( b)32(e)23( to)32( im)24(me)23(r)-16(s)16(e)23( )23(a )23(ta)23(r)-16(g)8(e)23(t)24( i)24(n)8( )23(a )-24(s)16(c)23(at)24(te)47(r)-16(i)24(n)-16(g)32( )-24(me)23(d)32(i)0(u)8(m)24(,)20( )-24(t)24(h)-16(e)47(r)-16(e)23(b)8(y)]TJ -3.5714 -1.1429 TD -0.016 Tc 0.218 Tw [(ex)-16(t)-24(e)-1(n)-40(d)-16(in)-16(g)-16( )47(i)-24(t)-24(s)16( )23(b)8(o)8(u)-16(n)-40(d)-16(ar)-40(y)32(.)-28( )23(I)7(n)-40( )23(th)-40(i)-24(s)16( ca)-24(s)-8(e)-1( th)-40(e o)8(p)-16(t)-24(o)8(d)-16(e)-1(s)-8( w)-8(o)8(u)-16(l)-24(d)-16( )23(n)-40(o)8(t)-24( b)8(e)-1( in)-40( co)8(n)-16(t)-24(a)-24(c)-1(t w)16(i)-24(th)-40( )23(th)-40(e ti)-24(s)-8(s)-8(u)-16(e,)]TJ T* 0.008 Tc 0.099 Tw [(r)-16(e)47(n)-16(d)8(e)47(r)-16(i)24(n)-16(g)32( )24(t)24(h)-16(e)47( )24(me)23(as)16(u)32(r)-16(e)23(m)0(e)47(n)8(t )24(s)16(u)8(s)16(c)23(e)23(p)8(tib)32(le)23( )24(to)32( )24(mo)32(tio)56(n)-16( )47(a)23(r)-16(t)24(i)0(f)31(a)0(c)23(t)0(s)16(.)-4( )24( Ev)32(e)23(n)8( if)31( t)24(h)8(is)16( c)23(o)32(u)8(l)0(d)8( b)32(e)23( o)32(v)32(e)23(r)-16(c)0(o)32(m)0(e)23(,)]TJ ET 1 1 1 rg 1 i 121.08 453.84 367.2 -180 re f* BT /F3 1 Tf 7.92 0 0 7.92 121.08 442.714 Tm 0 0 0 rg 0.013 Tc -0.021 Tw [( )-31( )-31( T)-17(a)28(b)-7(l)18(e 4.)21( I)-22(n)24(f)13(l)-12(u)24(e)2(n)24(ce of)13( )-31(a)28( rad)24(i)-12(a)28(l)18( co)-32(m)28(p)24(res)8(s)8(i)18(on)24( )-31(ma)28(n)24(e)-28(u)24(v)-2(er on)24( s)8(e)2(n)24(s)8(i)18(t)-18(i)18(v)-2(i)18(t)13(y)28( )-31(an)24(d)-7( ed)24(ge res)8(ol)18(u)24(t)13(i)18(o)-2(n)]TJ 6.4545 -2.3939 TD 0.003 Tc [(Ite)-8(m)18(s)]TJ 10.2727 1.1515 TD 0 Tc [(Be)-11(fo)-15(r)-11(e)]TJ -1.3939 -1.1515 TD 0.005 Tc [(Co)-10(m)20(p)16(r)-6(e)-6(ssi)10(o)-10(n)]TJ 17.6061 1.1515 TD 0 Tc [(A)25(fte)-11(r)]TJ -1.6667 -1.1515 TD 0.005 Tc [(Co)-10(m)20(p)16(r)-6(e)-6(ssi)10(o)-10(n)]TJ ET 129.96 441.12 0.48 -0.48 re f* 129.96 441.12 0.48 -0.48 re f* 130.44 441.12 102.96 -0.48 re f* 233.4 441.12 0.48 -0.48 re f* 233.88 441.12 62.4 -0.48 re f* 296.28 441.12 0.48 -0.48 re f* 296.76 441.12 188.64 -0.48 re f* 485.4 441.12 0.48 -0.48 re f* 485.4 441.12 0.48 -0.48 re f* 129.96 440.64 0.48 -24.48 re f* 233.4 440.64 0.48 -24.48 re f* 296.28 440.64 0.48 -24.48 re f* 485.4 440.64 0.48 -24.48 re f* BT /F5 1 Tf 7.92 0 0 7.92 155.64 408.412 Tm 0.041 Tc -0.018 Tw [(B)41(r)41(e)61(as)66(t)46( D)36(i)46(am)61(e)30(t)46(e)61(r)]TJ 2.3636 -1.1515 TD 0.015 Tc [(\()15(c)4(m)35(\))-9016(16)-14909(10)]TJ ET 129.96 416.16 0.48 -0.48 re f* 130.44 416.16 102.96 -0.48 re f* 233.4 416.16 0.48 -0.48 re f* 233.88 416.16 62.4 -0.48 re f* 296.28 416.16 0.48 -0.48 re f* 296.76 416.16 188.64 -0.48 re f* 485.4 416.16 0.48 -0.48 re f* 129.96 415.68 0.48 -24.48 re f* 233.4 415.68 0.48 -24.48 re f* 296.28 415.68 0.48 -24.48 re f* 485.4 415.68 0.48 -24.48 re f* BT 7.92 0 0 7.92 155.16 374.332 Tm -0.019 Tc 0.011 Tw [(T)-44(u)-34(mor)-19( D)-24(i)-14(a)-60(m)-29(et)-44(er)]TJ 2.4242 -1.1515 TD 0 Tc [(\(c)-11(m)20(\))]TJ 10.7879 1.1515 TD 0.015 Tc [(1.)23(6)]TJ 8.5455 1.1515 TD [(1.)23(0)]TJ -2.6667 -1.1515 TD -0.002 Tc [(\(P)9(ro)-17(p)-17(o)13(rti)-27(o)-17(n)13(a)-13(t)-27(e)18(ly)]TJ 1.3636 -1.1515 TD 0.014 Tc [(C)14(h)29(ange)34(d\))]TJ 9.2727 1.1515 TD 0.015 Tc [(1.)23(4)]TJ 7.3636 1.1515 TD [(1.)23(6)]TJ -1.8788 -1.1515 TD 0.025 Tc [(\()25(C)25(o)10(m)15(p)40(le)45(te)45(ly)]TJ 0.0606 -1.1515 TD 0.005 Tc [(Un)-10(c)25(h)20(a)-36(n)20(g)-10(e)-6(d)20(\))]TJ ET 129.96 391.2 0.48 -0.48 re f* 130.44 391.2 102.96 -0.48 re f* 233.4 391.2 0.48 -0.48 re f* 233.88 391.2 62.4 -0.48 re f* 296.28 391.2 0.48 -0.48 re f* 296.76 391.2 71.52 -0.48 re f* 368.28 391.2 0.48 -0.48 re f* 368.76 391.2 53.52 -0.48 re f* 422.28 391.2 0.48 -0.48 re f* 422.76 391.2 62.64 -0.48 re f* 485.4 391.2 0.48 -0.48 re f* 129.96 390.72 0.48 -29.52 re f* 233.4 390.72 0.48 -29.52 re f* 296.28 390.72 0.48 -29.52 re f* 368.28 390.72 0.48 -29.52 re f* 422.28 390.72 0.48 -29.52 re f* 485.4 390.72 0.48 -29.52 re f* BT 7.92 0 0 7.92 143.88 353.452 Tm -0.001 Tc 0.024 Tw [(T)-26(u)-16(m)19(o)14(r\226)-16(to)14(\226)-16( Bre)19(a)-42(s)24(t)-26( A)24(r)-32(e)19(a)]TJ 2.8182 -1.1515 TD -0.007 Tc -0.001 Tw [(R)-7(a)-18(tio)-22( \()-7(%)8(\))-8311(1)-8052(1)-6810(1)-22(.9)-22(6)-5628(2)-22(.5)-22(6)]TJ ET 129.96 361.2 0.48 -0.48 re f* 130.44 361.2 102.96 -0.48 re f* 233.4 361.2 0.48 -0.48 re f* 233.88 361.2 62.4 -0.48 re f* 296.28 361.2 0.48 -0.48 re f* 296.76 361.2 71.52 -0.48 re f* 368.28 361.2 0.48 -0.48 re f* 368.76 361.2 53.52 -0.48 re f* 422.28 361.2 0.48 -0.48 re f* 422.76 361.2 62.64 -0.48 re f* 485.4 361.2 0.48 -0.48 re f* 129.96 360.72 0.48 -23.52 re f* 233.4 360.72 0.48 -23.52 re f* 296.28 360.72 0.48 -23.52 re f* 368.28 360.72 0.48 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T)24(h)8(is)16( f)31(o)32(llo)8(w)40(s)]TJ 0 -1.1429 TD -0.015 Tc 0.146 Tw [(b)9(e)-23(ca)-23(u)-15(s)-7(e )24(ex)-15(t)-23(e)0(n)-39(s)-7(i)-23(o)9(n)-15( o)9(f)8( t)-23(h)-39(e ex)-15(t)-23(e)24(r)-15(n)-15(a)-23(l b)9(o)9(u)-15(n)-39(d)-15(ar)-39(y)33( w)-7(o)9(u)-15(l)-23(d)-15( r)-39(e)0(d)-15(u)-15(ce th)-39(e )24(ar)-39(ea r)-15(a)0(t)-23(i)-23(o)9( o)9(f)8( an)-39( R)9(O)-7(I)-15(,)-3( an)-15(d)-15(,)-3( a)-23(s)]TJ T* 0.008 Tc 0.052 Tw [(s)16(h)-16(o)32(w)40(n)-16( i)24(n)8( F)16(i)0(g)32(u)32(r)-16(e)23( 5)32(,)-4( )24(t)24(h)-16(is)40( c)23(o)32(u)8(l)0(d)8( )24(r)-16(e)23(d)8(u)8(c)23(e)23( s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56( to)32( th)-16(e)23( R)32(O)16(I)8(.)20( I)8(t)24( w)40(o)32(u)8(l)0(d)8( b)32(e)23( )-23(b)32(e)23(tte)23(r)-16( )-23(to)32( ac)23(h)8(i)0(e)23(v)32(e)23( )-23(an)]TJ T* -0.015 Tc 0.146 Tw [(ef)-15(f)-15(ect)-23(i)-23(v)-15(e i)-23(n)-39(c)24(r)-39(ea)-23(s)-7(e)0( in)-15( o)9(p)-15(t)-23(i)-23(cal)-23( th)-39(i)-23(c)0(k)9(n)-39(es)-7(s)-7( )-24(th)-15(r)-39(o)9(u)-15(g)9(h)-39(o)9(u)-15(t)1( )-24(th)-39(e m)-23(e)0(d)-15(i)-23(u)-15(m)1(. )-24(W)24(h)-39(il)-23(e )-24(it)-23( i)-23(s)-7( )-24(ev)9(i)-23(d)-15(en)-39(t )-24(th)-15(at)-23( )-24(o)9(n)-39(e)]TJ T* 0.008 Tc 0.075 Tw [(c)23(a)0(n)8(n)-16(o)32(t)24( )23(p)32(h)-16(y)56(s)16(ic)23(all)-24(y)56( e)23(n)-16(la)23(r)8(g)8(e)23( t)24(h)-16(e)47( tis)16(s)16(u)8(e)23(,)20( a)23( \223)23(v)32(ir)8(tu)8(a)23(l)0( e)47(n)-16(l)24(a)23(r)-16(g)8(e)23(m)0(e)47(n)-16(t)24(\224)23( c)23(a)23(n)-16( b)32(e)23( ac)23(c)23(o)32(mp)8(lis)40(h)-16(e)23(d)8( b)8(y)56( s)16(imp)8(ly)]TJ 0 -1.1191 TD 0.194 Tw [(illu)32(mi)24(n)8(a)23(ti)24(n)-16(g)32( t)24(h)-16(e)47( tis)16(s)16(u)8(e)23( u)32(n)8(d)8(e)23(r)8( s)16(t)0(u)32(d)8(y)56( )-24(w)40(ith)8( l)24(i)0(g)32(h)-16(t)24( o)32(f)31( a s)40(h)-16(o)32(r)8(te)23(r)8( w)40(a)0(v)32(e)23(le)23(n)-16(g)8(t)24(h)-16(.)20( )23( S)16(i)24(n)-16(c)23(e)23( t)24(h)8(is)16( )-24(w)40(o)32(u)8(l)0(d)]TJ 0 -1.1428 TD [(i)24(n)-16(c)23(r)-16(e)23(a)0(s)16(e)23( )47(t)24(h)-16(e)23( )23(to)32(ta)23(l o)32(p)8(t)24(i)0(c)23(a)0(l)24( t)24(h)8(ic)23(k)8(n)-16(e)23(s)16(s)16( w)40(i)0(t)24(h)-16(o)32(u)8(t )23(a)23( c)23(h)8(a)23(n)-16(g)8(e)23( )23(i)24(n)-16( p)32(h)-16(y)56(s)16(ic)23(al s)16(i)24(ze)23(, )23(a)23(n)8( i)24(m)0(p)32(r)-16(o)32(v)32(e)23(me)23(n)-16(t)0( )23(i)24(n)]TJ T* 0.028 Tw [(EF)16(W)23(H)40(M)16( in)8( ab)32(s)16(o)32(lu)8(te)23( te)47(r)-16(m)0(s)16( w)40(o)32(u)8(l)0(d)8( b)32(e)23( e)23(x)8(p)8(e)23(c)23(t)0(e)23(d)8(. I)31(n)8( t)24(h)-16(e)23( li)24(mi)24(t,)20( )-24(it)24( )-24(w)40(o)32(u)8(l)0(d)8( )-24(b)32(e)23( )-24(d)8(e)23(s)16(i)0(r)8(a)0(b)32(l)0(e)23( )-24(to)32( )-24(v)32(a)0(r)-16(y)56( )-24(t)24(h)-16(e)]TJ T* -0.015 Tc 0.027 Tw [(w)17(a)-23(v)-15(e)0(l)-23(e)0(n)-39(g)-15(th)-15( o)9(f)8( l)-23(i)-23(g)9(h)-39(t)1( in)-15( a)-23(cco)9(r)-39(d)-15(an)-39(ce w)17(i)-23(th)-15( th)-39(e d)9(i)-23(s)-7(t)1(an)-39(ce b)9(e)0(t)-47(w)17(e)-23(e)0(n)-39( a s)-7(o)9(u)9(r)-39(ce an)-39(d)9( d)-15(e)0(t)-23(ect)-23(o)9(r)-39(, )-24(s)-7(u)-15(ch)-15( )-24(th)-15(a)-23(t)1( )-24(a)]TJ T* 0.008 Tc 0.123 Tw [(n)-16(e)23(a)23(r)8(ly)56( )24(co)32(n)-16(s)16(ta)23(n)8(t)0( )48(to)32(tal)24( o)32(p)8(tic)23(al)24( t)24(h)8(ic)23(k)32(n)-16(e)23(s)16(s)16( is)16( )24(ac)47(h)-16(i)0(e)23(v)32(e)23(d)8( f)8(o)32(r)-16( a)23(l)0(l)24( s)16(o)32(u)8(r)-16(c)23(e)23(/)0(d)8(e)23(te)23(c)23(t)0(o)32(r)-16( p)32(a)0(i)24(r)-16(s)40(.)-4( )24( T)24(h)8(u)8(s)16(,)20( f)31(o)32(r)-16( a)]TJ T* 0 Tc 0.06 Tw [(de)15(t)-8(e)15(c)15(t)-8(o)24(r)-24( o)24(ppo)24(s)8(i)-8(t)-8(e)15( t)-8(h)-24(e)39( s)8(o)24(ur)-24(c)15(e)15(,)-12( w)32(a)-8(v)24(e)15(l)-8(e)15(n)-24(g)0(t)16(h)-24(s)8( )24(i)16(n)0( t)16(h)-24(e)15( N)8(I)0(R)24( )24(r)-24(e)15(gi)-8(o)48(n)-24( c)15(o)24(ul)-8(d b)24(e)15( e)15(m)-8(pl)-8(o)24(y)24(e)15(d,)-12( f)23(o)24(l)-8(l)-8(o)0(w)8(e)15(d )-23(by)]TJ T* 0.008 Tc 0.028 Tw [(d)8(e)23(te)23(c)23(tio)32(n)-16( o)32(f)31( mo)32(r)-16(e)23( b)32(l)0(u)8(e)23(\226)8(s)16(h)8(i)0(f)31(t)0(e)23(d)8( s)16(i)0(g)32(n)-16(a)23(l)0(s)16( b)32(y)56( d)8(e)23(tec)23(to)32(r)-16(s)16(. )24( S)16(e)23(le)23(c)23(tio)32(n)-16( o)32(f)31( t)24(h)-16(e)23( i)24(llu)32(mi)24(n)8(a)0(t)24(i)24(n)-16(g)32( )-24(w)40(a)0(v)32(e)23(le)23(n)-16(g)8(t)24(h)]TJ T* 0.242 Tw [(r)8(a)23(n)-16(g)8(e)23( c)23(o)32(u)8(l)0(d)8( b)32(e)23( ad)8(j)24(u)8(s)16(t)0(e)23(d)8( )24(i)24(n)-16( )24(ac)23(c)23(o)32(r)-16(d)8(a)23(n)-16(c)23(e)23( w)40(i)0(t)24(h)-16( )24(t)24(h)-16(e)23( p)32(h)-16(y)56(s)16(ic)23(al s)16(ize)23( o)32(f)31( a )24(ta)23(r)8(g)8(e)23(t )24(me)23(d)8(i)0(u)32(m)0(.)20( )-24(F)16(o)32(r)]TJ T* [(i)24(n)-16(s)16(t)0(a)23(n)-16(c)23(e)23(,)20( f)31(o)32(r)-16( e)23(x)8(am)24(i)24(n)8(atio)56(n)-16( o)32(f)31( la)23(r)-16(g)8(e)47( d)8(i)24(ame)23(te)47(r)-16( b)56(r)-16(e)23(a)0(s)16(t)0(s)16(,)20( mo)56(r)-16(e)23( r)-16(e)23(d)8(\226)8(s)40(h)-16(i)0(f)31(t)0(e)23(d)8( )-24(w)40(a)0(v)32(e)23(le)23(n)-16(g)8(t)24(h)8( r)-16(a)23(n)8(g)8(e)23(s)]TJ T* -0.015 Tc 0.194 Tw [(co)9(u)-15(l)-23(d)-15( )24(b)9(e)0( )24(em)-23(p)-15(l)-23(o)-15(y)9(ed)-15(,)-27( w)17(h)-39(er)-39(ea)-23(s)-7( f)8(o)9(r)-39( s)17(m)-23(al)-23(l)-23(e)24(r)-39( b)33(r)-39(ea)-23(s)-7(t)-23(s)-7( )24(th)-39(e w)17(a)-23(v)9(e)0(l)-23(e)0(n)-39(g)-15(th)-39( )24(r)-15(a)0(n)-39(g)-15(e w)17(o)9(u)-15(l)-23(d)-15( b)9(e)0( r)-39(e)0(la)-23(ti)-23(v)9(e)0(l)-47(y)]TJ T* 0 Tc 0.107 Tw [(b)24(l)-8(ue)15(\226s)8(h)-24(i)-8(f)23(t)-8(e)15(d)0(.)-12( )47( )24(It)16( )24(w)32(o)24(r)-24(t)16(h)-24( )24(n)-24(o)24(t)16(i)16(n)-24(g )24(t)16(h)0(a)-8(t)16( t)16(h)0(i)-8(s)8( s)8(c)15(h)-24(e)39(m)-8(e)15( c)15(o)24(ul)-8(d b)24(e)15( i)16(n)-24(f)23(l)-8(ue)15(n)-24(c)15(e)15(d)0( by)48( s)8(k)0(i)-8(n)0( c)15(o)24(l)-8(o)24(r)-24(,)-12( e)15(s)8(pe)15(c)15(i)-8(a)-8(l)16(l)-8(y)]TJ T* 0.008 Tc 0.028 Tw [(f)8(o)32(r)-16( )24(me)23(as)16(u)32(r)-16(e)23(m)0(e)23(n)8(ts)16( u)8(s)40(i)24(n)-16(g)32( w)40(a)0(v)32(e)23(le)23(n)-16(g)8(t)24(h)-16(s)16( s)40(h)-16(o)32(r)8(te)23(r)8( t)24(h)8(a)23(n)8( 6)8(5)8(0)32( )24(n)8(m)0(.)20( )24(Th)8(e)23( ab)32(s)16(o)32(r)-16(p)8(tio)32(n)8( )-24(p)32(r)-16(o)32(f)31(ile)23( )-24(o)32(f)31( )-24(me)23(lan)8(i)24(n)]TJ 0 -1.119 TD 0.009 Tc 0.003 Tw [(c)24(a)1(n)9( s)17(e)24(v)33(e)24(r)-15(e)24(l)-23(y)57( atte)48(n)-15(u)9(a)24(t)1(e)24( w)41(a)1(v)33(e)24(le)24(n)-15(g)9(t)25(h)-15(s)17( o)33(f)32( lig)33(h)9(t)1( )24(i)25(n)-15( )24(t)25(h)-15(e)24( v)33(i)1(s)17(i)1(b)33(l)1(e)24( )24(r)-15(e)24(g)9(i)1(o)33(n)9(, )24(t)25(h)-15(u)9(s)17( r)-15(e)24(d)9(u)9(c)24(i)25(n)9(g)9( t)25(h)-15(e)24( )-24(d)33(ime)48(n)-15(s)17(io)33(n)-15(s)]TJ 0 -1.1429 TD -0.015 Tc 0.027 Tw [(w)17(i)-23(t)-23(h)-39(in)-15( w)17(h)-15(i)-23(c)0(h)-15( a)-23(ccep)-15(t)-23(a)-23(b)9(l)-23(e)0( s)-7(i)-23(g)9(n)-15(a)-23(l)1( l)-23(e)0(v)9(e)0(l)-23(s)-7( ca)-23(n)-15( b)9(e)0( a)-23(c)0(q)-15(u)-15(i)1(r)-39(e)0(d)-15(.)]TJ 3.5714 -1.1429 TD 0.146 Tw [(Wh)-39(il)-23(e th)-39(e )24(d)-15(e)0(s)-7(c)0(r)-39(i)-23(b)9(e)0(d)-15( m)-23(u)9(l)-23(t)-23(i)1(\226)-15(w)17(a)-23(v)9(el)-23(en)-39(g)-15(t)1(h)-39( a)-23(p)-15(p)9(r)-39(o)9(a)-23(c)24(h)-39( )-24(co)9(u)-15(l)-23(d)-15( )-24(co)9(m)-23(p)-15(l)-23(i)-23(cat)-23(e )-24(d)9(a)-23(ta)-23( a)-23(c)0(q)-15(u)-15(i)-23(s)-7(i)1(t)-23(i)-23(o)9(n)]TJ -3.5714 -1.1429 TD 0.009 Tc 0.027 Tw [(a)24(n)-15(d)9( )24(a)24(n)9(aly)57(s)17(i)1(s)17( s)17(c)24(h)-15(e)24(me)24(s)17(,)-3( i)25(t)1( )24(is)17( w)41(o)33(r)-15(t)25(h)-15( )24(n)-15(o)33(t)25(i)25(n)-15(g)33( t)25(h)9(at)25(, )24(as)17( s)41(h)-15(o)33(w)41(n)-15( i)25(n)9( F)17(i)25(g)9(u)33(r)-15(e)24( 4)33(,)-3( )24(a )24(n)-15(e)48(a)24(r)-15(ly)57( )-24(te)24(n)-15(\226)9(f)32(o)33(ld)9( )-24(i)25(n)-15(c)48(r)-15(e)24(a)1(s)17(e)]TJ T* 0.003 Tw [(i)25(n)-15( s)17(e)48(n)-15(s)17(it)25(iv)33(ity)57( is)17( o)33(b)9(s)17(e)24(r)-15(v)33(e)24(d)9( u)9(p)9(o)33(n)-15( a)24(n)9( e)24(i)1(g)33(h)9(t\226)9(f)32(o)33(ld)9( i)25(n)-15(c)48(r)-15(e)24(a)1(s)17(e)24( i)25(n)9( o)33(p)9(tic)24(al)25( t)25(h)9(ic)24(k)33(n)-15(e)24(s)17(s)17(.)-3( )24( A)17(s)17( a)24(n)9( al)25(te)24(r)9(n)9(a)1(t)25(i)1(v)33(e)24(, )-24(a)]TJ T* 0.008 Tc 0.052 Tw [(s)16(imp)8(le)47(r)8( )24(s)16(c)23(h)-16(e)23(me)23(,)20( )24(a)23(n)8(d)8( )24(o)56(n)-16(e)23( )24(e)23(a)0(s)16(ily)56( )24(imp)32(le)23(me)47(n)-16(t)0(e)23(d)8(,)20( )24(is)40( )24(s)40(h)-16(o)32(w)40(n)-16( F)16(i)0(g)8(u)32(r)-16(e)23( 1)32(5)8(.)20( H)40(e)23(r)-16(e)23(, w)40(e)23( s)16(e)23(e)23(k)8( to)32( e)23(m)0(p)8(l)0(o)8(y)56( a)]TJ 0 -15.2143 TD 0.009 Tc 0.003 Tw [(s)17(i)1(n)9(g)9(l)1(e)24( o)33(r)9( a)24( f)32(e)24(w)41( illu)9(m)25(i)25(n)-15(a)24(t)1(i)25(n)9(g)9( w)41(a)1(v)33(e)24(le)24(n)-15(g)9(t)25(h)-15(s)17(.)21( )24( A)41(n)-15( o)33(p)9(ti)25(m)25(a)1(l)25( w)41(a)1(v)33(e)24(le)24(n)-15(g)9(t)25(h)-15( is)17( )-24(o)33(n)-15(e)24( )-24(f)32(o)33(r)-15( )-24(w)41(h)9(ic)48(h)-15( a)]TJ 33.7141 0 TD -0.015 Tc [(ccep)-15(t)-23(a)-23(b)9(l)-23(e)]TJ -33.7141 -1.1429 TD 0.008 Tc 0.147 Tw [(S)16(/)0(N)16( )24(le)23(v)32(e)23(ls)16( )24(a)23(r)-16(e)23( )24(m)24(a)0(i)24(n)8(t)24(a)0(i)24(n)-16(e)23(d)8( w)40(h)8(ile)23( )24(at)24( t)24(h)-16(e)47( s)16(a)23(me)23( ti)24(me)23( )24(t)24(h)-16(e)23( g)32(r)-16(e)23(a)23(t)0(e)23(s)16(t p)8(o)32(s)16(s)16(i)0(b)32(l)0(e)23( o)32(p)8(tic)23(al )24(t)24(h)-16(ic)23(k)32(n)-16(e)23(s)16(s)16( is)]TJ T* 0.337 Tw [(att)24(ai)24(n)-16(e)23(d)32(.)-4( )47( )24(W)47(h)-16(i)24(l)0(e)23( t)24(h)8(is)16( )24(me)23(t)24(h)-16(o)32(d)8( c)23(o)32(u)8(l)0(d)8( b)32(e)23( ad)8(ap)32(te)23(d)8( to)32( )24(me)23(as)16(u)32(r)-16(e)23(m)0(e)23(n)8(t)24( s)16(c)23(h)-16(e)23(me)23(s)16( u)8(s)40(i)24(n)-16(g)8( )24(p)8(l)24(a)23(n)-16(a)23(r)]TJ ET q 222.24 0 0 -120.72 184.2 453.84 cm /Im26 Do Q BT 7.92 0 0 7.92 241.32 326.812 Tm 0.014 Tc -0.022 Tw [(F)25(i)19(g.)22( 15.)22( O)-22(p)29(t)19(i)-11(m)34(a)3(l)-11( )-31(w)39(a)3(ve)34(l)-11(e)3(n)29(g)-1(t)19(h)-1( app)29(r)-17(o)29(ach)]TJ ET q 259.2 0 0 -155.52 175.08 273.84 cm /Im27 Do Q 1 1 1 rg 1 i 156.12 123.12 279.12 -23.52 re f* BT 7.92 0 0 7.92 167.4 112.732 Tm 0 0 0 rg 0.013 Tc -0.021 Tw [(F)24(i)18(g.)21( 16.)21( C)-17(o)-2(mb)28(i)-12(n)28(at)18(i)18(o)-2(n)28( )-31(of)13( r)13(a)2(d)28(i)18(al)-12( )-31(c)33(o)-2(mp)28(r)-18(e)2(s)8(s)38(i)-12(o)28(n and)28( )-31(o)28(p)-2(t)18(i)-12(m)33(a)2(l)18( )-31(w)38(a)-28(ve)33(l)-12(e)33(ng)28(t)-12(h)28( a)-28(p)28(p)28(r)-18(o)28(aches)]TJ ET endstream endobj 109 0 obj << /ProcSet [/PDF /Text /ImageC /ImageI] /Font << /F5 5 0 R >> /XObject << /Im26 104 0 R /Im27 106 0 R >> /ExtGState << /GS1 8 0 R >> /ColorSpace << /CS12 105 0 R >> >> endobj 105 0 obj [/Indexed /DeviceRGB 15 110 0 R] endobj 110 0 obj << /Filter /ASCII85Decode /Length 28 >> stream z!+qW!s8N(2s8W*!zzzzzzzz~> endstream endobj 112 0 obj << /Length 9251 >> stream 1 1 1 rg /GS1 gs 21 -66 612 792 re f BT /F5 1 Tf 10.08 0 0 10.08 117.48 711.6 Tm 0 0 0 rg 0.008 Tc 0.028 Tw [(c)23(o)32(mp)8(r)-16(e)23(s)16(s)16(i)0(o)32(n)-16(,)20( )24(as)16( )48(me)47(n)-16(t)24(io)32(n)-16(e)23(d)8(,)20( )24(t)24(h)8(is)16( )24(c)23(a)23(n)8( )24(c)23(o)32(mp)32(r)-16(o)32(mis)16(e)23( )24(t)24(h)-16(e)23( )48(at)24(ta)23(i)24(n)-16(ab)32(le)23( v)32(i)0(e)23(w)40( an)-16(g)32(l)0(e)23(.)20( B)32(e)23(tte)23(r)-16( )24(mig)32(h)8(t)24( b)32(e)23( to)]TJ 0 -1.1429 TD -0.015 Tc 0.289 Tw [(em)-23(p)-15(l)-23(o)-15(y)33( )24(a)-23( )48(r)-39(a)0(d)-15(i)-23(al)-23( )24(co)9(m)-23(p)9(r)-39(e)0(s)-7(s)-7(i)-23(o)9(n)-39( )48(a)-23(p)-15(p)9(r)-39(o)9(a)-23(c)24(h)-39(. )24( Th)-15(i)-23(s)-7( w)17(o)9(u)-15(l)-23(d)-15( p)9(r)-39(es)-7(er)-39(v)9(e)0( a)-23( )24(l)-23(a)0(r)-39(g)-15(e v)9(i)-23(ew)17( an)-39(g)-15(l)-23(e w)17(h)-15(i)-23(l)-23(e)]TJ T* 0.008 Tc 0.171 Tw [(p)8(e)23(r)-16(m)24(it)24(ti)24(n)-16(g)32( )24(i)24(m)0(p)32(l)0(e)23(m)0(e)23(n)8(ta)23(tio)56(n)-16( )24(o)32(f)31( s)16(o)32(me)23( f)8(o)32(r)-16(m)0( o)32(f)31( o)32(p)8(tima)23(l w)40(a)0(v)32(e)23(le)23(n)-16(g)8(t)24(h)8( s)16(c)23(h)-16(e)47(me)23(. )24(T)24(h)-16(is)40( ap)32(p)32(r)-16(o)32(a)0(c)23(h)8( is)]TJ T* 0.147 Tw [(illu)8(s)40(t)24(r)-16(a)23(te)23(d)8( i)24(n)8( F)16(i)24(g)8(u)32(r)-16(e)23( 1)8(6)32(. )24( I)31(n)8( t)24(h)-16(e)47( e)23(x)8(am)24(p)8(l)0(e)23( g)32(i)0(v)32(e)23(n)-16(,)20( a)23( l)24(a)23(r)-16(g)8(e)23( )-24(b)32(r)-16(e)23(a)0(s)40(t)0( )-24(c)23(o)32(n)8(tai)24(n)8(i)24(n)-16(g)32( a )-24(s)16(m)24(al)24(l tu)32(mo)32(r)-16( is)]TJ T* 0.004 Tc 0.103 Tw [(unde)19(r )24(e)19(x)4(a)19(m)-4(i)20(n)4(atio)52(n)-20(.)16( )47( )24(By)52( )24(e)19(x)4(e)19(r)-20(ti)20(n)-20(g)28( m)20(ild)28( )24(r)-20(a)19(di)20(al)20( c)19(o)28(mpr)-20(e)19(s)12(s)12(i)-4(o)28(n)4(,)-8( )24(t)20(h)-20(e)19( di)20(a)19(m)-4(e)19(t)-4(e)19(r)4( o)28(f)27( th)-20(e)19( b)52(r)-20(e)19(a)-4(s)12(t)-4( w)36(i)-4(l)20(l)-4( b)28(e)]TJ 0 -1.1191 TD 0.009 Tc 0.336 Tw [(r)-15(e)24(d)9(u)9(c)24(e)24(d)9(, )24(t)25(h)-15(e)48(r)-15(e)24(b)9(y)57( in)-15(c)24(r)-15(e)24(a)1(s)17(i)25(n)9(g)9( )24(av)33(ail)25(ab)33(le)24( s)17(i)1(g)33(n)9(al)25( le)24(v)33(e)24(ls)17(. D)17(e)24(p)9(e)48(n)-15(d)9(in)9(g)33( o)33(n)9( t)25(h)-15(e)48( )-24(c)24(o)33(mp)9(r)-15(e)24(s)17(s)17(i)1(b)33(ili)25(ty)]TJ 0 -1.1428 TD -0.015 Tc 0.36 Tw [(ch)-39(ar)-15(a)-23(c)0(t)-23(e)0(r)-15(i)-23(s)-7(t)-23(i)-23(c)0(s)-7( o)9(f)8( th)-39(e tu)-15(m)-23(o)9(r)-15(,)-3( th)-39(e )24(r)-39(e)0(s)-7(u)-15(lt)-23(an)-15(t)-23( s)17(t)-23(at)-23(e ma)-23(y)33( )-48(w)17(e)0(l)-23(l)-23( )-24(p)9(r)-39(o)9(d)-15(u)-15(ce )-24(a)-23(n)-15( )-24(e)24(n)-15(h)-39(a)0(n)-39(cem)-23(e)24(n)-39(t )-24(in)]TJ T* 0.008 Tc 0.075 Tw [(s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56(, b)32(u)8(t r)-16(e)23(s)16(o)32(lu)8(tio)56(n)-16( c)23(o)32(u)8(l)0(d)8( s)16(u)8(f)31(f)31(e)23(r)-16(,)-4( )23(at)24( le)23(as)16(t)24( i)24(n)8( r)-16(e)23(l)24(a)0(t)24(i)0(v)32(e)23( )-24(te)23(r)-16(m)0(s)40(.)-4( )-24(H)40(o)8(w)40(e)0(v)8(e)23(r)-16(,)20( )-24(b)8(y)56( )-24(ad)8(j)24(u)8(s)16(t)0(i)24(n)-16(g)8( t)24(h)-16(e)]TJ T* 0.052 Tw [(illu)32(mi)24(n)8(a)23(tio)32(n)8( )24(w)40(a)0(v)32(e)23(le)23(n)-16(g)8(t)24(h)-16(,)20( )24(t)24(h)-16(e)47( to)32(ta)23(l o)32(p)8(tic)47(al)24( t)24(h)8(ic)23(k)8(n)-16(e)23(s)16(s)16( c)23(a)23(n)8( b)32(e)23( i)24(n)-16(c)23(r)-16(e)23(a)0(s)16(e)23(d)8(,)20( t)24(h)-16(e)47(r)-16(e)23(b)8(y)56( imp)32(r)-16(o)32(v)32(i)0(n)-16(g)32( b)32(o)32(t)0(h)]TJ T* 0.004 Tw [(s)16(e)23(n)-16(s)16(it)24(iv)32(ity)56( an)-16(d)32( )24(r)-16(e)23(s)16(o)32(lu)8(tio)32(n)8( i)24(n)8( ab)32(s)16(o)32(lu)8(te)23( te)47(r)-16(m)0(s)40(.)]TJ /F7 1 Tf 0 -1.7901 TD 0.075 Tw [(I)8(n)8(flu)32(en)32(ce)23( o)8(f)24( C)8(o)8(n)32(tr)16(a)8(s)16(t)24( Ag)32(en)8(ts)40(.)]TJ /F5 1 Tf 11.8571 0.052 TD [( )23( W)47(h)-16(i)24(l)0(e)23( u)8(s)16(e)23( o)32(f)31( co)32(n)-16(t)24(r)8(a)0(s)16(t)0( )23(ag)8(e)47(n)-16(ts)]TJ /F7 1 Tf 12.1667 -0.052 TD 0 Tc 0.083 Tw [( pe)-8(r)32( )-24(s)8(e)-8( )]TJ /F5 1 Tf 3.1905 0.052 TD -0.016 Tc 0.099 Tw [(w)16(a)-24(s)-8( n)-40(o)8(t )-24(ex)-16(a)-24(min)-40(ed)-16( in)-40( th)-40(i)-24(s)]TJ -27.2143 -1.1429 TD 0 Tc 0.06 Tw [(s)8(t)-8(udy)48(,)-12( i)-8(n)-24(s)32(i)-8(g)24(h)-24(t)16( )24(r)-24(e)15(ga)15(rdi)16(n)-24(g)24( t)16(h)-24(e)39(i)16(r)-24( e)15(xpe)15(c)15(t)-8(e)15(d)0( e)15(f)23(fe)15(c)15(t)-8(i)-8(v)0(e)15(n)-24(e)15(s)8(s)8( c)15(a)-8(n b)24(e)15( de)15(r)-24(i)-8(v)24(e)15(d )-23(o)24(n)0( )-23(t)16(h)-24(e)15( )-23(b)24(a)-8(s)8(i)-8(s)32( )-23(o)24(f)23( )-23(t)-8(h)-24(e)15( ra)15(n)-24(g)0(e)]TJ T* 0.25 Tw [(of)23( )24(t)-8(u)0(m)-8(o)24(r )24(c)15(o)24(n)-24(t)16(ra)-8(s)8(t)16( l)-8(e)15(v)24(e)15(l)-8(s)8( s)8(t)-8(udi)-8(e)15(d)0(.)12( )24(Co)24(n)-24(t)16(ra)-8(s)8(t)16( a)15(g)0(e)15(n)0(t)-8(s)8( )24(a)15(r)-24(e)15( t)16(r)0(a)-8(d)0(i)16(t)-8(i)-8(o)24(na)15(l)-8(l)-8(y)48( e)15(m)-8(pl)-8(oy)24(e)15(d)0( t)-8(o)24( e)15(nha)15(n)-24(c)15(e)]TJ T* 0.008 Tc 0.075 Tw [(me)23(as)16(u)32(r)-16(e)23(m)0(e)23(n)8(t s)16(e)47(n)-16(s)16(i)24(tiv)32(ity)56(. 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